2019
“Radiotherapy for older women (ROW)”: A risk calculator for women with early-stage breast cancer
Wang SY, Abujarad F, Chen T, Evans SB, Killelea BK, Mougalian SS, Fraenkel L, Gross C. “Radiotherapy for older women (ROW)”: A risk calculator for women with early-stage breast cancer. Journal Of Geriatric Oncology 2019, 11: 850-859. PMID: 31899199, PMCID: PMC7263974, DOI: 10.1016/j.jgo.2019.12.010.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerRisk calculatorLocal recurrenceBreast cancerOlder womenTumor characteristicsBreast cancer-specific outcomesReceipt of radiotherapyCancer-specific outcomesEarly breast cancerIndividual patient's riskBenefits of radiotherapyAdvisory CommitteeLife expectancyOnline risk calculatorLong-term survivalShared decision makingBenefit of RTOlder adult womenRadiotherapy statusCause mortalityOverall survivalRecurrence reductionFunctional statusPatient risk
2012
Factors associated with life expectancy (LE) < 3 months (mo) among older adults receiving palliative chemotherapy (chemo).
Hurria A, Hardt M, Tew W, Mohile S, Owusu C, Gross C, Gajra A, Lichtman S, Katheria V, Ramani R, Zavala L, Klepin H. Factors associated with life expectancy (LE) < 3 months (mo) among older adults receiving palliative chemotherapy (chemo). Journal Of Clinical Oncology 2012, 30: 9034-9034. DOI: 10.1200/jco.2012.30.15_suppl.9034.Peer-Reviewed Original ResearchUnintentional weight lossPoor physical functionMultivariate logistic regressionAdvanced cancerLife expectancyPhysical functionWeight lossBivariate analysisLogistic regressionOlder adultsGeriatric assessment variablesMulti-site cohort studyLimited life expectancyPhysical function measuresFunctional status measuresOlder ptsPalliative chemoPalliative chemotherapyPalliative intentCohort studyPatient ageLow albuminFunctional statusOptimal treatmentRisk factorsAnemia and functional disability in older adults with cancer.
Owusu C, Tew W, Hardt M, Mohile S, Klepin H, Gross C, Gajra A, Lichtman S, Ramani R, Katheria V, Zavala L, Hurria A. Anemia and functional disability in older adults with cancer. Journal Of Clinical Oncology 2012, 30: 9109-9109. DOI: 10.1200/jco.2012.30.15_suppl.9109.Peer-Reviewed Original ResearchFunctional disabilityProspective studyOlder adultsMulti-center prospective studyUnintentional weight lossCorrection of anemiaRandomized-controlled trialPre-treatment variablesOlder ptsChemotherapy toxicityGeriatric assessmentPatient agePrimary outcomeMean HbFunctional statusInstrumental activitiesDaily livingAnemiaAdvanced stageMultivariate analysisAge 65Secondary analysisModifiable strategiesBivariate analysisLogistic regression
2009
Geriatric assessment of older adults with cancer: Baseline data from a 500 patient multicenter study
Hurria A, Mohile S, Lichtman S, Owusu C, Klepin H, Gross C, Hansen K, Klapper S, Togawa K, Tew W. Geriatric assessment of older adults with cancer: Baseline data from a 500 patient multicenter study. Journal Of Clinical Oncology 2009, 27: 9546-9546. DOI: 10.1200/jco.2009.27.15_suppl.9546.Peer-Reviewed Original ResearchGeriatric assessmentOlder adultsBrief geriatric assessmentNew chemotherapy regimenStage IV diseaseComorbid medical conditionsMultivariate logistic regressionCommon tumor typesNon-white raceGross cognitive impairmentBlessed Orientation-MemoryChemotherapy regimenChemotherapy toxicityMetastatic diseaseOlder patientsPatient ageMulticenter studyFunctional statusProspective dataOncology practiceTreatment decisionsInstrumental activitiesMedical conditionsGYN cancersHigh school education