2023
Considerations of Sex and Gender in FDA Tobacco Regulation
Davis D, Krishnan-Sarin S, Mazure C. Considerations of Sex and Gender in FDA Tobacco Regulation. JAMA 2023, 329: 2017-2018. PMID: 37233997, PMCID: PMC11094658, DOI: 10.1001/jama.2023.6803.Peer-Reviewed Original ResearchThe value of teaching the influence of sex and gender on health outcomes
Martin K, Marshall A, Mazure C. The value of teaching the influence of sex and gender on health outcomes. The Lancet Haematology 2023, 10: e318-e319. PMID: 37142343, PMCID: PMC10154001, DOI: 10.1016/s2352-3026(23)00055-8.Peer-Reviewed Original ResearchPre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers
Hennein R, Lowe S, Feingold J, Feder A, Peccoralo L, Ripp J, Mazure C, Pietrzak R. Pre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers. Journal Of Psychiatric Research 2023, 162: 88-94. PMID: 37105023, DOI: 10.1016/j.jpsychires.2023.04.009.Peer-Reviewed Original ResearchConceptsMajor depressive disorderPosttraumatic stress disorderProspective cohort studyHealthcare providersCohort studyLarge tertiary care hospitalPsychological sequelaeSymptoms of MDDMental health risk factorsTertiary care hospitalProbable major depressive disorderWomen's healthcare providersHealth risk factorsFrontline healthcare providersCare hospitalRisk factorsDepressive disorderGender differencesStress disorderAnxiety disordersWomenSequelaeCOVID-19DisordersCOVID-19 pandemicObesity Risk Among West Point Graduates Later in Life
Szivak TK, Thomas MM, Pietrzak RH, Nguyen DR, Ryan DM, Mazure CM. Obesity Risk Among West Point Graduates Later in Life. The Journal Of Strength And Conditioning Research 2023, 37: 1284-1291. PMID: 33278268, DOI: 10.1519/jsc.0000000000003824.Peer-Reviewed Original ResearchConceptsBody mass indexPhysical activityObesity ratesMetabolic equivalentsObesity riskHigher self-reported physical activityInternational Physical Activity Questionnaire-Short FormSelf-reported physical activityWeekly metabolic equivalentLean body massU.S. adult populationQuestionnaire-Short FormLifetime obesityMass indexObesity statusBMI valuesJ Strength Cond ResHealth initiativesAdult populationGreater riskWomenMenObesityShort formResiliency factors
2022
Gender-related association among childhood maltreatment, brain structure and clinical features in bipolar disorder
Colic L, Clark A, Sankar A, Rathi DJ, Goldman DA, Kim JA, Villa LM, Edmiston EK, Lippard ETC, Pittman B, Constable RT, Mazure CM, Blumberg HP. Gender-related association among childhood maltreatment, brain structure and clinical features in bipolar disorder. European Neuropsychopharmacology 2022, 63: 35-46. PMID: 36037590, PMCID: PMC9593266, DOI: 10.1016/j.euroneuro.2022.07.186.Peer-Reviewed Original ResearchConceptsClinical featuresBipolar disorderCM severityChildhood maltreatmentLeft hippocampusPost-traumatic stress disorder (PTSD) comorbidityBrain structuresStructural magnetic resonance imagingGender-related associationMagnetic resonance imagingGray matter structuresChildhood Trauma QuestionnaireGender-related differencesCM exposureHealthy controlsClinical assessmentDisorder comorbidityMood symptomsPathophysiological modelGender-related effectsResonance imagingHippocampusFrontal poleTrauma QuestionnaireSeverityPrecision medicine requires understanding how both sex and gender influence health
Stachenfeld NS, Mazure CM. Precision medicine requires understanding how both sex and gender influence health. Cell 2022, 185: 1619-1622. PMID: 35561661, DOI: 10.1016/j.cell.2022.04.012.Peer-Reviewed Original Research
2021
Are Women Less Psychologically Resilient Than Men? Background Stressors Underlying Gender Differences in Reports of Stress-Related Psychological Sequelae.
Lowe SR, Hennein R, Feingold JH, Peccoralo LA, Ripp JA, Mazure CM, Pietrzak RH. Are Women Less Psychologically Resilient Than Men? Background Stressors Underlying Gender Differences in Reports of Stress-Related Psychological Sequelae. The Journal Of Clinical Psychiatry 2021, 83 PMID: 34936244, DOI: 10.4088/jcp.21br14098.Peer-Reviewed Original ResearchA sex-stratified analysis of suicidal ideation correlates among deployed post-9/11 veterans: Results from the survey of experiences of returning veterans
Hoffmire CA, Monteith LL, Denneson LM, Holliday R, Park CL, Mazure CM, Hoff RA. A sex-stratified analysis of suicidal ideation correlates among deployed post-9/11 veterans: Results from the survey of experiences of returning veterans. Journal Of Affective Disorders 2021, 294: 824-830. PMID: 34375209, DOI: 10.1016/j.jad.2021.07.015.Peer-Reviewed Original ResearchMeaningful military engagement among male and female post‐9/11 veterans: An examination of correlates and implications for resilience
Finkelstein‐Fox L, Sinnott SM, Lee SY, Carney LM, Park CL, Mazure CM, Hoff R. Meaningful military engagement among male and female post‐9/11 veterans: An examination of correlates and implications for resilience. Journal Of Clinical Psychology 2021, 77: 2167-2186. PMID: 33960411, DOI: 10.1002/jclp.23150.Peer-Reviewed Original ResearchThis is Your Brain in Meltdown
Arnsten A, Mazure CM, Sinha R. This is Your Brain in Meltdown. Scientific American 2021, 306: 48-53. PMID: 22486116, PMCID: PMC4774859, DOI: 10.1038/scientificamerican0412-48.Peer-Reviewed Original ResearchPost‐9/11 military veterans' adjustment to civilian life over time following separation from service
Park CL, Sacco SJ, Finkelstein‐Fox L, Sinnott SM, Scoglio AAJ, Lee SY, Gnall KE, Mazure C, Shirk SD, Hoff RA, Kraus SW. Post‐9/11 military veterans' adjustment to civilian life over time following separation from service. Journal Of Clinical Psychology 2021, 77: 2077-2095. PMID: 33871869, DOI: 10.1002/jclp.23144.Peer-Reviewed Original ResearchInfluences of religiousness/spirituality on mental and physical health in OEF/OIF/OND military veterans varies by sex and race/ethnicity
Park CL, Sacco SJ, Kraus SW, Mazure CM, Hoff RA. Influences of religiousness/spirituality on mental and physical health in OEF/OIF/OND military veterans varies by sex and race/ethnicity. Journal Of Psychiatric Research 2021, 138: 15-23. PMID: 33798785, DOI: 10.1016/j.jpsychires.2021.03.034.Peer-Reviewed Original ResearchWomen, opioid use and addiction
Goetz TG, Becker JB, Mazure CM. Women, opioid use and addiction. The FASEB Journal 2021, 35: e21303. PMID: 33433026, DOI: 10.1096/fj.202002125r.Peer-Reviewed Original ResearchConceptsOpioid useChronic painPrescription opioidsEffective public health policiesOngoing opioid epidemicPublic health policyComparison of womenWidespread prescribingOpioid medicationsPublic health crisisOpioid epidemicOpioid addictionOpioidsTreatment opportunitiesTreatment approachesSynthetic opioidsMedicationsPainPsychosocial effectsHealth policyWomen's exposureWomenCurrent coronavirus pandemicHealth crisisMen
2019
Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies
Schmaal L, van Harmelen AL, Chatzi V, Lippard ETC, Toenders YJ, Averill LA, Mazure CM, Blumberg HP. Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies. Molecular Psychiatry 2019, 25: 408-427. PMID: 31787757, PMCID: PMC6974434, DOI: 10.1038/s41380-019-0587-x.Peer-Reviewed Original ResearchConceptsVentral prefrontal cortexSuicidal ideationSuicidal thoughtsDorsal PFCDorsal anterior cingulate cortexAnterior cingulate cortexHigh-risk circumstancesBrain alterationsBrain areasLarger sample sizeCingulate cortexMolecular alterationsMental disordersNarrative reviewSuicide thoughtsPrefrontal cortexNeurobiological substratesInhibition of behaviorSuicide attempt behaviorBrain systemsCortexInsulaImpairmentComprehensive reviewLongitudinal designIt all adds up: Addressing the roles of cumulative traumatic experiences on military veterans
Scoglio AAJ, Shirk SD, Mazure C, Park CL, Molnar BE, Hoff RA, Kraus SW. It all adds up: Addressing the roles of cumulative traumatic experiences on military veterans. Child Abuse & Neglect 2019, 98: 104227. PMID: 31648113, DOI: 10.1016/j.chiabu.2019.104227.Peer-Reviewed Original ResearchIs Emotion Dysregulation Associated With Suicidal Ideation in Post 9/11 Veterans?
Decker SE, Hoff R, Martino S, Mazure CM, Park CL, Porter E, Kraus SW. Is Emotion Dysregulation Associated With Suicidal Ideation in Post 9/11 Veterans? Archives Of Suicide Research 2019, 25: 126-140. PMID: 31556798, DOI: 10.1080/13811118.2019.1661895.Peer-Reviewed Original ResearchSex differences in amphetamine-induced dopamine release in the dorsolateral prefrontal cortex of tobacco smokers
Zakiniaeiz Y, Hillmer AT, Matuskey D, Nabulsi N, Ropchan J, Mazure CM, Picciotto MR, Huang Y, McKee SA, Morris ED, Cosgrove KP. Sex differences in amphetamine-induced dopamine release in the dorsolateral prefrontal cortex of tobacco smokers. Neuropsychopharmacology 2019, 44: 2205-2211. PMID: 31269510, PMCID: PMC6897943, DOI: 10.1038/s41386-019-0456-y.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDA releasePositron emission tomographyD2R availabilityDorsolateral prefrontal cortexMale smokersFemale smokersTobacco smokingPrefrontal cortexAmphetamine-induced DA releaseAmphetamine-induced dopamine releaseCortical DA releaseMesocortical DA systemEffects of nicotineSmoking-related behaviorsMesolimbic dopamine systemLong-term abstinenceSex differencesGender-specific treatmentFemale nonsmokersTobacco smokersAmphetamine administrationDopamine releaseNeurochemical mechanismsNonsmokersSmokersThe federal plan for health science and technology’s response to the opioid crisis: understanding sex and gender differences as part of the solution is overlooked
Becker JB, Mazure CM. The federal plan for health science and technology’s response to the opioid crisis: understanding sex and gender differences as part of the solution is overlooked. Biology Of Sex Differences 2019, 10: 3. PMID: 30616693, PMCID: PMC6322277, DOI: 10.1186/s13293-018-0215-5.Peer-Reviewed Original ResearchConceptsOpioid crisisClinical care providersCurrent opioid epidemicNeurobiology of painGender-specific treatmentGender differencesNeonatal exposureOpioid useOpioid epidemicOpioid addictionCare providersEpidemiological dataPrevention strategiesHealth SciencesGender-based treatmentSuccessful responseSexPrevention implicationsReportTreatmentAddictionFurther researchResponseOpioidsPain
2018
Do unit and post-deployment social support influence the association between deployment sexual trauma and suicidal ideation?
Monteith LL, Hoffmire CA, Holliday R, Park CL, Mazure CM, Hoff RA. Do unit and post-deployment social support influence the association between deployment sexual trauma and suicidal ideation? Psychiatry Research 2018, 270: 673-681. PMID: 30384288, DOI: 10.1016/j.psychres.2018.10.055.Peer-Reviewed Original ResearchConceptsSuicidal ideationSexual traumaUnit supportPost-deployment supportColumbia-Suicide Severity Rating ScaleLifetime suicide attemptsSeverity Rating ScalePosttraumatic stress disorder (PTSD) symptomsSocial supportSexual trauma survivorsElevated riskPossible depressionSuicide attemptsTraumaRating ScaleDisorder symptomsSocial support influenceIdeationIntensive monitoringTrauma survivorsMenAssociationWomenPresent studySurvey of experiencesBidirectionality of Pain Interference and PTSD Symptoms in Military Veterans: Does Injury Status Moderate Effects?
Lee SY, Finkelstein-Fox L, Park CL, Mazure CM, Huedo-Medina TB, Hoff R. Bidirectionality of Pain Interference and PTSD Symptoms in Military Veterans: Does Injury Status Moderate Effects? Pain Medicine 2018, 20: 934-943. PMID: 30016463, PMCID: PMC6497092, DOI: 10.1093/pm/pny133.Peer-Reviewed Original ResearchConceptsPain interferencePTSD symptomsInjury statusDeployment-related injuryCross-sectional studyPost-traumatic stress disorder symptomsPhysical symptom managementSubset of veteransBidirectional relationshipPotential bidirectional relationshipWorse PTSD symptomsOperation New DawnSymptom managementOperation Enduring FreedomVeteran populationFemale veteransSymptomsOperation Iraqi FreedomInjured veteransInjuryPresent longitudinal studyTime pointsPhone interviewsPsychological interventionsDisorder symptoms