2024
Spesolimab treatment for the prevention of flares in people with generalized pustular psoriasis (GPP): a plain language summary of the Effisayil™ 2 study
Morita A, Strober B, Burden A, Choon S, Anadkat M, Marrakchi S, Tsai T, Gordon K, Thaçi D, Zheng M, Hu N, Haeufel T, Thoma C, Lebwohl M. Spesolimab treatment for the prevention of flares in people with generalized pustular psoriasis (GPP): a plain language summary of the Effisayil™ 2 study. Future Rare Diseases 2024, 4: frd57. DOI: 10.2217/frd-2023-0023.Peer-Reviewed Original ResearchGeneralized pustular psoriasisGeneralized pustular psoriasis flaresPustular psoriasisHigh dosesQuality of lifePrevention of flaresCompared to placeboLife-threatening diseasePrevent flaresSpesolimabGPP flaresClinical studiesMedium doseSkin symptomsDoseUnwanted effectsPlaceboPsoriasisSymptomsDrugPustulesWeeksDisease
2005
The treatment of psoriasis with etanercept.
Strober B. The treatment of psoriasis with etanercept. Seminars In Cutaneous Medicine And Surgery 2005, 24: 28-36. PMID: 15900796, DOI: 10.1016/j.sder.2005.01.003.Peer-Reviewed Original ResearchConceptsTreatment of psoriasisTumor necrosis factor receptorTumor necrosis factor-alpha inhibitorsNecrosis factor-alpha inhibitorsSigns of psoriasisAppropriate patient selectionPathogenesis of psoriasisNecrosis factor receptorEtanercept therapySevere psoriasisTolerability profilePatient selectionRisk ratioTNF-alphaAlpha inhibitorsClinical trialsEtanerceptProinflammatory activityPsoriasisBetter efficacyHigh dosesFactor receptorPatientsSignificant reductionTreatment