2021
674 Single-cell RNA sequencing (scRNA-seq) of sarcoidosis skin biopsies reveals key pathogenic cytokines and potential treatment targets
Wang A, King B, Damsky W. 674 Single-cell RNA sequencing (scRNA-seq) of sarcoidosis skin biopsies reveals key pathogenic cytokines and potential treatment targets. Journal Of Investigative Dermatology 2021, 141: s117. DOI: 10.1016/j.jid.2021.02.704.Peer-Reviewed Original Research
2020
The Promise of JAK Inhibitors for Treatment of Sarcoidosis and Other Inflammatory Disorders with Macrophage Activation: A Review of the Literature.
Wang A, Singh K, Ibrahim W, King B, Damsky W. The Promise of JAK Inhibitors for Treatment of Sarcoidosis and Other Inflammatory Disorders with Macrophage Activation: A Review of the Literature. The Yale Journal Of Biology And Medicine 2020, 93: 187-195. PMID: 32226347, PMCID: PMC7087061.Peer-Reviewed Original ResearchConceptsInflammatory disordersMacrophage activationJAK inhibitorsCertain inflammatory disordersTreatment of sarcoidosisFormation of granulomasCrohn's diseaseClinical evidenceNecrobiosis lipoidicaInflammatory cytokinesDependent cytokinesGranuloma annulareGranuloma formationInterferon gammaJAK inhibitionJAK-STAT pathwaySarcoidosisDisordersCytokinesInhibitorsConstitutive activationDiseaseActivationDramatic improvementGranulomas