2001
Ibuprofen as a Chemesthetic Stimulus: Evidence of a Novel Mechanism of Throat Irritation
Breslin P, Gingrich T, Green B. Ibuprofen as a Chemesthetic Stimulus: Evidence of a Novel Mechanism of Throat Irritation. Chemical Senses 2001, 26: 55-65. PMID: 11124216, DOI: 10.1093/chemse/26.1.55.Peer-Reviewed Original ResearchConceptsCapsaicin-sensitive receptorsThroat irritationRatings of irritationReceptor mechanismsSensory irritationNon-steroidal anti-inflammatory drug ibuprofenIrritationAnti-inflammatory drug ibuprofenOral irritantsThroatReceptorsNovel mechanismStimulationIbuprofenChemesthetic propertiesChemesthetic stimuliBuffering agentDrug ibuprofenPrickAgentsChemesthetic effects
1998
Temporal characteristics of capsaicin desensitization and stimulus-induced recovery in the oral cavity
Green B, Rentmeister-Bryant H. Temporal characteristics of capsaicin desensitization and stimulus-induced recovery in the oral cavity. Physiology & Behavior 1998, 65: 141-149. PMID: 9811376, DOI: 10.1016/s0031-9384(98)00162-0.Peer-Reviewed Original ResearchConceptsCapsaicin desensitizationIntermittent stimulationMicroM capsaicinTopical analgesicsOral cavitySignificant desensitizationCapsaicinClinical useRecurrent stimulationDesensitizationStimulationBlock recoveryExposureMinutesRapid exposureTest stimuliStimuliTongueCandy formulationChemonociceptionAnalgesicsSecond testTreatment stimuliIrritation
1997
Perceived Irritation during Ingestion of Capsaicin or Piperine: Comparison of Trigeminal and Non-trigeminal Areas
Rentmeister-Bryant H, Green B. Perceived Irritation during Ingestion of Capsaicin or Piperine: Comparison of Trigeminal and Non-trigeminal Areas. Chemical Senses 1997, 22: 257-266. PMID: 9218138, DOI: 10.1093/chemse/22.3.257.Peer-Reviewed Original ResearchConceptsAnterior tongueIrritation ratingsIngestion of capsaicinRostro-caudal axisVagus nerveOral mucosaOropharyngeal regionPosterior tongueIntensity of sensationsChemical irritantsCapsaicinChemosensory irritationIrritationIngestionThroatIrritantsPiperineTongueChemesthetic stimuliResponsivenessPrevious findingsNerveTrigeminalMucosa
1990
Spatial summation of chemical irritation and itch produced by topical application of capsaicin
Green B. Spatial summation of chemical irritation and itch produced by topical application of capsaicin. Attention, Perception, & Psychophysics 1990, 48: 12-18. PMID: 2165586, DOI: 10.3758/bf03205007.Peer-Reviewed Original ResearchConceptsTopical applicationStimulus areaSpatial summationSensation of irritationHeat painSensations of itchingStinging/Afferent systemsChemical irritationCutaneous sensationFrequency of reportsCapsaicinIrritationNumber of stimuliStatistical significanceIntensity of irritationFilter paper discsItchSensationSkinModest increasePrevious reportsStimulus sizeStimulationPaper discs
1989
Salt as an oral irritant
Green B, Gelhard B. Salt as an oral irritant. Chemical Senses 1989, 14: 259-271. DOI: 10.1093/chemse/14.2.259.Peer-Reviewed Original Research