2007
The Role of the Receptor Activator of Nuclear Factor-κB Ligand/Osteoprotegerin Cytokine System in Primary Hyperparathyroidism
Nakchbandi IA, Lang R, Kinder B, Insogna KL. The Role of the Receptor Activator of Nuclear Factor-κB Ligand/Osteoprotegerin Cytokine System in Primary Hyperparathyroidism. The Journal Of Clinical Endocrinology & Metabolism 2007, 93: 967-973. PMID: 18073309, PMCID: PMC2266956, DOI: 10.1210/jc.2007-1645.Peer-Reviewed Original ResearchConceptsNuclear factor-kappaB ligandPrimary hyperparathyroidismBone lossReceptor activatorTotal femurIL-6Bone resorptionIL-6 soluble receptorMild primary hyperparathyroidismBone mineral densitySoluble receptor activatorMechanism of actionIL-6sRSRANKL levelsSerum levelsBone turnoverMineral densityCytokine systemSoluble receptorHyperparathyroidismNormal rangeSkeletal responsivenessBiochemical markersPatientsGreater riskFilling a Void: Thyroid Cancer Surgery Information on the Internet
Yeo H, Roman S, Air M, Maser C, Trapasso T, Kinder B, Sosa JA. Filling a Void: Thyroid Cancer Surgery Information on the Internet. World Journal Of Surgery 2007, 31: 1187-1193. PMID: 17446991, DOI: 10.1007/s00268-007-9010-x.Peer-Reviewed Original ResearchConceptsCurrent clinical practice guidelinesImportant public health issueRole of lymphadenectomyThyroid cancer surgeryClinical practice guidelinesSurgery/anesthesiaSurgery informationThyroid cancer incidenceT-testPublic health issuePredictors of qualityStudent's t-testCancer surgeryHealth-related decisionsEndocrine surgeonsThyroid surgeonsCancer incidencePotential complicationsUnivariate analysisInter-rater reliabilityPractice guidelinesDemographic dataSignificant associationQuality scoresHealth issuesOutdated and Incomplete: A Review of Thyroid Cancer on the World Wide Web
Air M, Roman SA, Yeo H, Maser C, Trapasso T, Kinder B, Sosa JA. Outdated and Incomplete: A Review of Thyroid Cancer on the World Wide Web. Thyroid 2007, 17: 259-265. PMID: 17381360, DOI: 10.1089/thy.2006.0300.Peer-Reviewed Original Research
2005
Chapter 87 Endocrine Emergencies: Hypoglycemic and Hyperglycemic Crises
Inzucchi S, Kinder B. Chapter 87 Endocrine Emergencies: Hypoglycemic and Hyperglycemic Crises. 2005, 789-799. DOI: 10.1016/b978-0-7216-0139-7.50091-0.Peer-Reviewed Original Research
2004
Hypercalcemia and Hypercalcemia Treatment
Kinder B. Hypercalcemia and Hypercalcemia Treatment. 2004, 517-529. DOI: 10.1016/b0-12-475570-4/00643-0.Peer-Reviewed Original ResearchGastrointestinal calcium absorptionNormal calcium regulationRenal calcium excretionUrgent clinical problemHypercalcemia treatmentCalcium excretionRole of calciumCalcium absorptionNew bone formationBone resorptionClinical problemHypercalcemiaAppropriate managementBone formationCalcium regulationHomeostatic systemPatientsExcretionResorption
2002
Circulating Levels of Interleukin-6 Soluble Receptor Predict Rates of Bone Loss in Patients with Primary Hyperparathyroidism
Nakchbandi IA, Mitnick MA, Lang R, Gundberg C, Kinder B, Insogna K. Circulating Levels of Interleukin-6 Soluble Receptor Predict Rates of Bone Loss in Patients with Primary Hyperparathyroidism. The Journal Of Clinical Endocrinology & Metabolism 2002, 87: 4946-4951. PMID: 12414855, DOI: 10.1210/jc.2001-011814.Peer-Reviewed Original ResearchConceptsBone lossIL-6sRTotal femurIL-6IL-6 soluble receptorPrimary hyperparathyroidism resultsYearly bone lossSubset of patientsUntreated hyperparathyroidismDisease activityPrimary hyperparathyroidismUpper tertileCytokine axisHyperparathyroidismSoluble receptorPatientsBiochemical markersClassical biochemical markersWhole groupFemurPredict rateGreater rateRecent studiesTertileGroupAssessment of RET/PTC Oncogene Activation and Clonality in Thyroid Nodules with Incomplete Morphological Evidence of Papillary Carcinoma A Search for the Early Precursors of Papillary Cancer
Fusco A, Chiappetta G, Hui P, Garcia-Rostan G, Golden L, Kinder BK, Dillon DA, Giuliano A, Cirafici AM, Santoro M, Rosai J, Tallini G. Assessment of RET/PTC Oncogene Activation and Clonality in Thyroid Nodules with Incomplete Morphological Evidence of Papillary Carcinoma A Search for the Early Precursors of Papillary Cancer. American Journal Of Pathology 2002, 160: 2157-2167. PMID: 12057919, PMCID: PMC1850819, DOI: 10.1016/s0002-9440(10)61164-9.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAnimalsBase SequenceCarcinoma, PapillaryCloning, MolecularDrosophila ProteinsGene Expression Regulation, NeoplasticGenetic MarkersHumansMembrane ProteinsMiceMolecular Sequence DataNeoplasm InvasivenessNuclear Receptor CoactivatorsOncogene ProteinsOncogene Proteins, FusionPatched ReceptorsPatched-1 ReceptorProtein-Tyrosine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-retRabbitsReceptor Protein-Tyrosine KinasesReceptors, Cell SurfaceReverse Transcriptase Polymerase Chain ReactionThyroid NeoplasmsThyroid NoduleTranscription FactorsConceptsLaser capture microdissectionPapillary cancerRET/PTC1RET immunoreactivityThyroid nodulesCarcinoma featuresMicroscopic fociPapillary carcinomaInvasive papillary cancerCytological alterationsReverse transcriptase-polymerase chain reactionRET activationRET/PTC3 rearrangementsTranscriptase-polymerase chain reactionRET/PTC3Analysis of clonalityRET/PTC oncogene activationPrecursor lesionsEntire lesionTumor fociPolyclonal tumorsAdenomatous nodulesMorphological changesSame tumorMorphological signs
2001
Presidential address: A biography of calcium
Kinder B. Presidential address: A biography of calcium. Surgery 2001, 130: 899-906. PMID: 11742315, DOI: 10.1067/msy.2001.118955.Peer-Reviewed Original Research
1999
Inhibition of protein phosphatase 1 decreases PTH secretion from isolated dispersed parathyroid cells
Matovcik L, Rhee S, Schaefer J, da Cruz e Silva E, Kinder B. Inhibition of protein phosphatase 1 decreases PTH secretion from isolated dispersed parathyroid cells. Molecular And Cellular Endocrinology 1999, 154: 171-177. PMID: 10509811, DOI: 10.1016/s0303-7207(98)00224-x.Peer-Reviewed Original ResearchConceptsParathyroid hormone secretionOkadaic acidPP-1PP-1 activityPTH secretionPlasma membrane markerHormone secretionParathyroid cellsProtein phosphataseBasal PTH secretionTarget of inhibitionSubcellular fractionationPermeabilized cellsBovine cellsMembrane markersSecretory granulesIntact bovineIntact humanSecretionSelective inhibitorCellsPhosphataseOkadaicInhibitionMarkers
1998
Genetic and Biochemical Screening for Endocrine Disease: II. Ethical Issues
Kinder B. Genetic and Biochemical Screening for Endocrine Disease: II. Ethical Issues. World Journal Of Surgery 1998, 22: 1208-1211. PMID: 9841745, DOI: 10.1007/s002689900546.Peer-Reviewed Original ResearchDetection of thyroglobulin, thyroid peroxidase, and RET/PTC1 mRNA transcripts in the peripheral blood of patients with thyroid disease.
Tallini G, Ghossein RA, Emanuel J, Gill J, Kinder B, Dimich AB, Costa J, Robbins R, Burrow GN, Rosai J. Detection of thyroglobulin, thyroid peroxidase, and RET/PTC1 mRNA transcripts in the peripheral blood of patients with thyroid disease. Journal Of Clinical Oncology 1998, 16: 1158-66. PMID: 9508203, DOI: 10.1200/jco.1998.16.3.1158.Peer-Reviewed Original ResearchConceptsReverse transcription-polymerase chain reactionPeripheral bloodThyroid diseaseThyroid carcinomaBenign thyroid nodulesThyroid peroxidaseThyroid nodulesRT-PCR positivityPeripheral blood samplesDiagnosis of carcinomaTranscription-polymerase chain reactionPapillary thyroid carcinomaBenign thyroid lesionsRET/PTC1Cervical lymphInitial surgeryClinical evidenceExtrathyroid extensionNodular hyperplasiaBenign lesionsPatientsCarcinomaBlood collectionMRNA transcriptsThyroid lesions
1997
Reconstitution of Calcium-Regulated Parathyroid Hormone Secretion from Streptolysin-O-Permeabilized Parathyroid Cells by Guanosine 5′-O-(Thio)Triphosphate*
Matovcik L, Rhee S, Schaefer J, Kinder B. Reconstitution of Calcium-Regulated Parathyroid Hormone Secretion from Streptolysin-O-Permeabilized Parathyroid Cells by Guanosine 5′-O-(Thio)Triphosphate*. Endocrinology 1997, 138: 1170-1179. DOI: 10.1210/en.138.3.1170.Peer-Reviewed Original ResearchIntracellular Ca2+ levelsPTH secretionParathyroid cellsCa2+ levelsPhysiological intracellular Ca2+ levelsHormone secretionRate of PTH secretionCalcium/calmodulin-dependent protein kinase IIIncreased PTH secretionInhibit PTH secretionParathyroid hormone secretionExtracellular Ca2+Regulation of hormone secretionCa2+ concentrationDose-dependent mannerProtein kinase IICa2+-dependent regulationAmbient Ca2+ concentrationStreptolysin OIn vitro model systemPTH releaseIntracellular Ca2SLO-permeabilized cellsKinase IISecretionReconstitution of calcium-regulated parathyroid hormone secretion from streptolysin-O-permeabilized parathyroid cells by guanosine 5'-O-(thio)triphosphate.
Matovcik L, Rhee S, Schaefer J, Kinder B. Reconstitution of calcium-regulated parathyroid hormone secretion from streptolysin-O-permeabilized parathyroid cells by guanosine 5'-O-(thio)triphosphate. Endocrinology 1997, 138: 1170-9. PMID: 9048624, DOI: 10.1210/endo.138.3.4971.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacterial ProteinsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium-Calmodulin-Dependent Protein KinasesCattleCell Membrane PermeabilityCyclic AMPCytosolEnergy MetabolismGuanine NucleotidesGuanosine 5'-O-(3-Thiotriphosphate)Osmolar ConcentrationParathyroid GlandsParathyroid HormoneParotid GlandStreptolysinsTime FactorsConceptsPTH secretionParathyroid cellsIntracellular Ca2Hormone secretionParathyroid hormone secretionGuanosine 5'Dose-dependent mannerCalcium/calmodulin-dependent protein kinase IIPTH releaseCalmodulin-dependent protein kinase IIExtracellular Ca2Physiological intracellular Ca2Protein kinase IISecretionAmbient Ca2Low Ca2Ca2GTPγSCellsInverse relationshipCytosolic cofactorsKinase IIAddition of GTPγSAbsence of GTPγSDependent regulation
1996
Mechanism of technetium 99m sestamibi parathyroid imaging and the possible role of p-glycoprotein
Mitchell B, Cornelius E, Zoghbi S, Murren J, Ghoussoub R, Flynn S, Kinder B. Mechanism of technetium 99m sestamibi parathyroid imaging and the possible role of p-glycoprotein. Surgery 1996, 120: 1039-1045. PMID: 8957492, DOI: 10.1016/s0039-6060(96)80052-3.Peer-Reviewed Original ResearchConceptsAbnormal parathyroid tissueParathyroid tissueP-glycoproteinGlycoprotein expressionMechanism of technetiumTreatment of recurrentAbnormal parathyroidParathyroid visualizationPersistent hyperparathyroidismParathyroid explorationConsecutive patientsParathyroid glandsHistologic examinationSestamibi uptakeThyroid glandSestamibiTechnetium sestamibiNormal thyroidMonoclonal antibodiesImmunohistochemistryTouch preparationsTissue originTissuePossible roleRapid confirmationA 73-year-old man with hyperglycemia, skin rashes, anemia and weight loss
Henry JG, Xue N, Kinder BK, Inzucchi SE. A 73-year-old man with hyperglycemia, skin rashes, anemia and weight loss. The Journal Of Clinical Endocrinology & Metabolism 1996, 81: 2428-2433. PMID: 8675556, DOI: 10.1210/jcem.81.7.8675556.Peer-Reviewed Original Research
1995
localization Studies in Patients with Hyperparathyroidism
Mitchell B, Kinder B, Merrell R. localization Studies in Patients with Hyperparathyroidism. Surgical Clinics Of North America 1995, 75: 483-498. PMID: 7747254, DOI: 10.1016/s0039-6109(16)46635-1.Peer-Reviewed Original ResearchConceptsMultiple gland diseasePrevious neck surgeryCervical explorationSuspicious glandsParathyroid explorationPersistent diseasePreoperative localizationMinimal morbiditySestamibi SPECTHigh success rateNeck surgeryInvasive proceduresGland diseaseParathyroid anatomySurgical handsPatientsSkilled surgical handsSuccess rateHyperparathyroidismComplementary testsDiseaseGlandLimited sensitivityLocalization studiesMorbidityDARPP‐32 (dopamine and cAMP‐regulated phosphoprotein, M r 32,000) is a membrane protein in the bovine parathyroid
Matovcik L, Hemmings H, Kinder B. DARPP‐32 (dopamine and cAMP‐regulated phosphoprotein, M r 32,000) is a membrane protein in the bovine parathyroid. FEBS Letters 1995, 364: 67-74. PMID: 7750546, DOI: 10.1016/0014-5793(95)00359-h.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain ChemistryCattleDopamine and cAMP-Regulated Phosphoprotein 32Fluorescent Antibody TechniqueIsoenzymesMembrane ProteinsMembranesMicroscopy, ImmunoelectronNerve Tissue ProteinsParathyroid GlandsPhosphoprotein PhosphatasesPhosphoproteinsProtein Phosphatase 1Protein PrenylationSubcellular FractionsTissue DistributionConceptsProtein phosphatase 1 gammaDARPP-32Protein phosphatase-1 inhibitorPhosphatase-1 inhibitorImmunocytochemical localization studiesMembrane proteinsIntracellular membranesPlasma membraneMetabolic labelingProtein presentLocalization studiesBovine parathyroidImmunoblot analysisSoluble formParticulate fractionDistinct formsMembraneCentral nervous systemCellsM NaClNervous systemParathyroid cellsCytoplasmProteinVesiclesPrimary hyperparathyroidism: preoperative localization using technetium-sestamibi scanning
Mitchell B, Kinder B, Cornelius E, Stewart A. Primary hyperparathyroidism: preoperative localization using technetium-sestamibi scanning. The Journal Of Clinical Endocrinology & Metabolism 1995, 80: 7-10. PMID: 7829642, DOI: 10.1210/jcem.80.1.7829642.Peer-Reviewed Original Research
1994
Antibodies to an epitope on synapsin I detect a protein associated with the endocytic compartment in non-neuronal cells.
Matovcik LM, Karapetian O, Czernik AJ, Marino CR, Kinder BK, Gorelick FS. Antibodies to an epitope on synapsin I detect a protein associated with the endocytic compartment in non-neuronal cells. European Journal Of Cell Biology 1994, 65: 327-40. PMID: 7536673.Peer-Reviewed Original ResearchConceptsClone 9 cellsEndocytic compartmentsPotential substrate proteinsDependent protein kinase IISynapsin ISmall intracellular vesiclesProtein kinase IIRat liver endosomesSubstrate proteinsPhosphorylation sequenceNon-neuronal cellsCLIP-170Intracellular vesiclesKinase IILarge endosomesPostnuclear supernatantEndosomesSensitive compartmentLiver endosomesProteinConfocal microscopyCell linesVesiclesIntestinal enterocytesCompartmentsParathyroid carcinoma arising from parathyroid hyperplasia: Autoinfarction following intravenous treatment with pamidronate
de Papp A, Kinder B, LiVolsi V, Gupta S, Stewart A. Parathyroid carcinoma arising from parathyroid hyperplasia: Autoinfarction following intravenous treatment with pamidronate. The American Journal Of Medicine 1994, 97: 399-400. PMID: 7942947, DOI: 10.1016/0002-9343(94)90312-3.Peer-Reviewed Original Research