1999
Inhibition of protein phosphatase 1 decreases PTH secretion from isolated dispersed parathyroid cells
Matovcik L, Rhee S, Schaefer J, da Cruz e Silva E, Kinder B. Inhibition of protein phosphatase 1 decreases PTH secretion from isolated dispersed parathyroid cells. Molecular And Cellular Endocrinology 1999, 154: 171-177. PMID: 10509811, DOI: 10.1016/s0303-7207(98)00224-x.Peer-Reviewed Original ResearchConceptsParathyroid hormone secretionOkadaic acidPP-1PP-1 activityPTH secretionPlasma membrane markerHormone secretionParathyroid cellsProtein phosphataseBasal PTH secretionTarget of inhibitionSubcellular fractionationPermeabilized cellsBovine cellsMembrane markersSecretory granulesIntact bovineIntact humanSecretionSelective inhibitorCellsPhosphataseOkadaicInhibitionMarkers
1997
Reconstitution of calcium-regulated parathyroid hormone secretion from streptolysin-O-permeabilized parathyroid cells by guanosine 5'-O-(thio)triphosphate.
Matovcik L, Rhee S, Schaefer J, Kinder B. Reconstitution of calcium-regulated parathyroid hormone secretion from streptolysin-O-permeabilized parathyroid cells by guanosine 5'-O-(thio)triphosphate. Endocrinology 1997, 138: 1170-9. PMID: 9048624, DOI: 10.1210/endo.138.3.4971.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacterial ProteinsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium-Calmodulin-Dependent Protein KinasesCattleCell Membrane PermeabilityCyclic AMPCytosolEnergy MetabolismGuanine NucleotidesGuanosine 5'-O-(3-Thiotriphosphate)Osmolar ConcentrationParathyroid GlandsParathyroid HormoneParotid GlandStreptolysinsTime FactorsConceptsPTH secretionParathyroid cellsIntracellular Ca2Hormone secretionParathyroid hormone secretionGuanosine 5'Dose-dependent mannerCalcium/calmodulin-dependent protein kinase IIPTH releaseCalmodulin-dependent protein kinase IIExtracellular Ca2Physiological intracellular Ca2Protein kinase IISecretionAmbient Ca2Low Ca2Ca2GTPγSCellsInverse relationshipCytosolic cofactorsKinase IIAddition of GTPγSAbsence of GTPγSDependent regulation
1996
Mechanism of technetium 99m sestamibi parathyroid imaging and the possible role of p-glycoprotein
Mitchell B, Cornelius E, Zoghbi S, Murren J, Ghoussoub R, Flynn S, Kinder B. Mechanism of technetium 99m sestamibi parathyroid imaging and the possible role of p-glycoprotein. Surgery 1996, 120: 1039-1045. PMID: 8957492, DOI: 10.1016/s0039-6060(96)80052-3.Peer-Reviewed Original ResearchConceptsAbnormal parathyroid tissueParathyroid tissueP-glycoproteinGlycoprotein expressionMechanism of technetiumTreatment of recurrentAbnormal parathyroidParathyroid visualizationPersistent hyperparathyroidismParathyroid explorationConsecutive patientsParathyroid glandsHistologic examinationSestamibi uptakeThyroid glandSestamibiTechnetium sestamibiNormal thyroidMonoclonal antibodiesImmunohistochemistryTouch preparationsTissue originTissuePossible roleRapid confirmation
1995
localization Studies in Patients with Hyperparathyroidism
Mitchell B, Kinder B, Merrell R. localization Studies in Patients with Hyperparathyroidism. Surgical Clinics Of North America 1995, 75: 483-498. PMID: 7747254, DOI: 10.1016/s0039-6109(16)46635-1.Peer-Reviewed Original ResearchConceptsMultiple gland diseasePrevious neck surgeryCervical explorationSuspicious glandsParathyroid explorationPersistent diseasePreoperative localizationMinimal morbiditySestamibi SPECTHigh success rateNeck surgeryInvasive proceduresGland diseaseParathyroid anatomySurgical handsPatientsSkilled surgical handsSuccess rateHyperparathyroidismComplementary testsDiseaseGlandLimited sensitivityLocalization studiesMorbidityDARPP‐32 (dopamine and cAMP‐regulated phosphoprotein, M r 32,000) is a membrane protein in the bovine parathyroid
Matovcik L, Hemmings H, Kinder B. DARPP‐32 (dopamine and cAMP‐regulated phosphoprotein, M r 32,000) is a membrane protein in the bovine parathyroid. FEBS Letters 1995, 364: 67-74. PMID: 7750546, DOI: 10.1016/0014-5793(95)00359-h.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain ChemistryCattleDopamine and cAMP-Regulated Phosphoprotein 32Fluorescent Antibody TechniqueIsoenzymesMembrane ProteinsMembranesMicroscopy, ImmunoelectronNerve Tissue ProteinsParathyroid GlandsPhosphoprotein PhosphatasesPhosphoproteinsProtein Phosphatase 1Protein PrenylationSubcellular FractionsTissue DistributionConceptsProtein phosphatase 1 gammaDARPP-32Protein phosphatase-1 inhibitorPhosphatase-1 inhibitorImmunocytochemical localization studiesMembrane proteinsIntracellular membranesPlasma membraneMetabolic labelingProtein presentLocalization studiesBovine parathyroidImmunoblot analysisSoluble formParticulate fractionDistinct formsMembraneCentral nervous systemCellsM NaClNervous systemParathyroid cellsCytoplasmProteinVesiclesPrimary hyperparathyroidism: preoperative localization using technetium-sestamibi scanning
Mitchell B, Kinder B, Cornelius E, Stewart A. Primary hyperparathyroidism: preoperative localization using technetium-sestamibi scanning. The Journal Of Clinical Endocrinology & Metabolism 1995, 80: 7-10. PMID: 7829642, DOI: 10.1210/jcem.80.1.7829642.Peer-Reviewed Original Research
1994
Parathyroid carcinoma arising from parathyroid hyperplasia: Autoinfarction following intravenous treatment with pamidronate
de Papp A, Kinder B, LiVolsi V, Gupta S, Stewart A. Parathyroid carcinoma arising from parathyroid hyperplasia: Autoinfarction following intravenous treatment with pamidronate. The American Journal Of Medicine 1994, 97: 399-400. PMID: 7942947, DOI: 10.1016/0002-9343(94)90312-3.Peer-Reviewed Original Research
1993
Histologic, flow cytometric, and genetic criteria in endocrine surgery.
Flynn S, Kinder B. Histologic, flow cytometric, and genetic criteria in endocrine surgery. Current Opinion In General Surgery 1993, 115-20. PMID: 7583941.Peer-Reviewed Original ResearchConceptsEndocrine neoplasmsClinical scoring systemCases of malignancyPathologic criteriaHistologic criteriaEndocrine surgeryBiologic behaviorDifferential diagnosisEndocrine neoplasiaPathologic interpretationCytologic appearanceScoring systemFlow cytometricFlow cytometryPrognosisTumorsNeoplasmsDiagnosisIndividual casesAccurate assessmentSurgeryMalignancyNeoplasiaPathogenesisHistologic
1989
Expression of Transcripts Encoding a Parathyroid Hormone-Related Peptide in Abnormal Human Parathyroid Tissues*
IKEDA K, ARNOLD A, MANGIN M, KINDER B, VYDELINGUM N, BRENNAN M, BROADUS A. Expression of Transcripts Encoding a Parathyroid Hormone-Related Peptide in Abnormal Human Parathyroid Tissues*. The Journal Of Clinical Endocrinology & Metabolism 1989, 69: 1240-1248. PMID: 2573615, DOI: 10.1210/jcem-69-6-1240.Peer-Reviewed Original Research
1987
Calcium-Calmodulin-Dependent Protein Kinase in Hyperplastic Human Parathyroid Glands
KINDER BK, DELAHUNT NG, JAMIESON JD, GORELICK FS. Calcium-Calmodulin-Dependent Protein Kinase in Hyperplastic Human Parathyroid Glands. Endocrinology 1987, 120: 170-177. PMID: 3096699, DOI: 10.1210/endo-120-1-170.Peer-Reviewed Original Research
1985
New applications of total parathyroidectomy and autotransplantation: Use in proximal renal tubular dysfunction
Kinder B, Rasmussen H. New applications of total parathyroidectomy and autotransplantation: Use in proximal renal tubular dysfunction. World Journal Of Surgery 1985, 9: 156-164. PMID: 3838609, DOI: 10.1007/bf01656271.Peer-Reviewed Original ResearchConceptsTotal parathyroidectomyMetabolic bone diseaseBone diseaseProximal renal tubular dysfunctionGraft-dependent hypercalcemiaSevere bone diseaseVitamin D intoxicationTreatment of hyperparathyroidismCases of recurrentRenal tubular dysfunctionNew clinical settingsParathyroid massPersistent hyperparathyroidismRecurrent diseaseSecondary hyperparathyroidismPolyendocrine syndromeRenal osteodystrophySubtotal resectionFurther recurrenceParathyroid hyperplasiaTubular dysfunctionLocal anesthesiaEffective treatmentGraft tissueHigh incidence
1980
Diagnostic and Therapeutic Approaches to Primary Hyperparathyroidism
Kinder B, Broadus A, Lang R, Rasmussen H. Diagnostic and Therapeutic Approaches to Primary Hyperparathyroidism. Surgical Clinics Of North America 1980, 60: 1285-1295. PMID: 7434165, DOI: 10.1016/s0039-6109(16)42251-6.Peer-Reviewed Original ResearchMeSH KeywordsCalciumDihydroxycholecalciferolsHumansHyperparathyroidismMethodsParathyroid GlandsParathyroid Hormone