2001
A model for gene therapy of human hereditary lymphedema
Karkkainen M, Saaristo A, Jussila L, Karila K, Lawrence E, Pajusola K, Bueler H, Eichmann A, Kauppinen R, Kettunen M, Ylä-Herttuala S, Finegold D, Ferrell R, Alitalo K. A model for gene therapy of human hereditary lymphedema. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 12677-12682. PMID: 11592985, PMCID: PMC60113, DOI: 10.1073/pnas.221449198.Peer-Reviewed Original ResearchMeSH KeywordsAdenoviridaeAmino Acid SequenceAnimalsDependovirusDisease Models, AnimalEndothelial Growth FactorsGenetic TherapyHumansLymphedemaMaleMiceMice, Inbred BALB CMice, Inbred C3HMolecular Sequence DataNerve Tissue ProteinsNeuropilin-1Receptor Protein-Tyrosine KinasesReceptors, Growth FactorVascular Endothelial Growth Factor CVascular Endothelial Growth Factor Receptor-3
2000
Developmental expression of Pim kinases suggests functions also outside of the hematopoietic system
Eichmann A, Yuan L, Bréant C, Alitalo K, Koskinen P. Developmental expression of Pim kinases suggests functions also outside of the hematopoietic system. Oncogene 2000, 19: 1215-1224. PMID: 10713710, DOI: 10.1038/sj.onc.1203355.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAmino Acid SequenceAnimalsCloning, MolecularEctodermEmbryo, NonmammalianEmbryonic and Fetal DevelopmentEmbryonic DevelopmentGene Expression Regulation, DevelopmentalHematopoiesisHumansMiceMolecular Sequence DataNervous SystemOrgan SpecificityProtein Serine-Threonine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-pim-1QuailRatsTranscription, GeneticConceptsExpression patternsSerine/threonine kinaseDeduced amino acid sequenceDynamic expression patternHematopoietic systemPim-1Amino acid sequencePim family kinasesEarly developmental stagesFunctional redundancyThreonine kinaseFamily kinasesEmbryonic developmentStrong homologyNovel functionAcid sequenceExpression sitesPIM genesAvian embryosDevelopmental expressionDevelopmental stagesPIM familyPIM kinasesCDNAKinase
1998
Avian VEGF-C: cloning, embryonic expression pattern and stimulation of the differentiation of VEGFR2-expressing endothelial cell precursors
Eichmann A, Corbel C, Jaffredo T, Bréant C, Joukov V, Kumar V, Alitalo K, le Douarin N. Avian VEGF-C: cloning, embryonic expression pattern and stimulation of the differentiation of VEGFR2-expressing endothelial cell precursors. Development 1998, 125: 743-752. PMID: 9435294, DOI: 10.1242/dev.125.4.743.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceCell DifferentiationCloning, MolecularDNA, ComplementaryEndothelial Growth FactorsEndothelium, VascularGene Expression Regulation, DevelopmentalIn Situ HybridizationMesodermMiceMolecular Sequence DataProtein BindingQuailReceptor Protein-Tyrosine KinasesReceptors, Cell SurfaceReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorRecombinant ProteinsSequence Homology, Amino AcidStem CellsVascular Endothelial Growth Factor CVascular Endothelial Growth Factor Receptor-3
1996
Molecular cloning of Quek 1 and 2, two quail vascular endothelial growth factor (VEGF) receptor-like molecules
Eichmann A, Marcelle C, Bréant C, Le Douarin N. Molecular cloning of Quek 1 and 2, two quail vascular endothelial growth factor (VEGF) receptor-like molecules. Gene 1996, 174: 3-8. PMID: 8863722, DOI: 10.1016/0378-1119(96)00159-x.Peer-Reviewed Original Research
1994
Distinct developmental expression of a new avian fibroblast growth factor receptor
Marcelle C, Eichmann A, Halevy O, Bréant C, Le Douarin N. Distinct developmental expression of a new avian fibroblast growth factor receptor. Development 1994, 120: 683-694. PMID: 8162862, DOI: 10.1242/dev.120.3.683.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBlotting, NorthernChick EmbryoCloning, MolecularCoturnixFibroblast Growth Factor 2GastrulaGene ExpressionIn Situ HybridizationMolecular Sequence DataMusclesPolymerase Chain ReactionReceptor Protein-Tyrosine KinasesReceptor, Fibroblast Growth Factor, Type 4Receptors, Fibroblast Growth FactorConceptsFibroblast growth factor receptorGrowth factor receptorMesoderm-derived structuresSkeletal muscle lineageFibroblast growth factor receptor (FGFR) familySatellite cellsStage-specific mannerDistinct developmental expressionFactor receptorNew memberIg-like domainsEarly myotomeGrowth factor receptor familyPattern of expressionSkeletal muscleEmbryonic RNAPrimitive streak stageLateral epiblastMuscle lineageDays of developmentFactor receptor familyPrimary transcriptEarly avian developmentAvian developmentFibroblast growth factor
1992
Molecular cloning of a family of protein kinase genes expressed in the avian embryo.
Marcelle C, Eichmann A. Molecular cloning of a family of protein kinase genes expressed in the avian embryo. Oncogene 1992, 7: 2479-87. PMID: 1281306.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBlastocystChick EmbryoChickensCloning, MolecularEmbryo, NonmammalianGene ExpressionMolecular Sequence DataMultigene FamilyNervous SystemNeural CrestOligodeoxyribonucleotidesOrgan SpecificityPhylogenyPoly APolymerase Chain ReactionProtein KinasesProtein-Tyrosine KinasesQuailReceptors, Cell SurfaceRNARNA, MessengerSequence Homology, Amino AcidSequence Homology, Nucleic AcidTranscription, GeneticConceptsReceptor tyrosine kinasesPKS genesGrowth factor receptorPutative receptor tyrosine kinaseTyrosine kinaseSerine/threonine kinaseProtein kinase sequencesEarly vertebrate developmentProtein kinase geneCytosolic tyrosine kinasesFactor receptorFibroblast growth factor receptorGrowth factor receptor tyrosine kinasePlatelet-derived growth factor receptor alphaGrowth factor receptor alphaNorthern blot analysisPattern of expressionReceptor-like moleculesVertebrate developmentInsulin-like growth factor type I receptorKinase sequencesType I receptorThreonine kinaseMore transcriptsAvian homolog