2021
Addressing psychosocial health in the treatment and care of adolescents with obesity
Jebeile H, Cardel MI, Kyle TK, Jastreboff AM. Addressing psychosocial health in the treatment and care of adolescents with obesity. Obesity 2021, 29: 1413-1422. PMID: 34431234, DOI: 10.1002/oby.23194.Peer-Reviewed Original ResearchConceptsPsychosocial healthPsychosocial outcomesMajority of adolescentsCare of adolescentsBody imagePsychological supportPsychosocial impactObesity treatment interventionsAdolescentsTreatment interventionsSelf-directed weight lossFuture researchPsychosocial comorbiditiesReduced symptomsWeight management optionsMulticomponent interventionWeight lossFurther weight gainQuality of lifeTreatment servicesObesity treatmentImpact of interventionsInterventionAntiobesity pharmacotherapiesObesity care
2016
Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents
Jastreboff AM, Sinha R, Arora J, Giannini C, Kubat J, Malik S, Van Name MA, Santoro N, Savoye M, Duran EJ, Pierpont B, Cline G, Constable RT, Sherwin RS, Caprio S. Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents. Diabetes 2016, 65: 1929-1939. PMID: 27207544, PMCID: PMC5384636, DOI: 10.2337/db15-1216.Peer-Reviewed Original ResearchConceptsObese adolescentsLean adolescentsGlucose ingestionInsulin levelsBrain perfusionBrain regionsSugar-sweetened beverage consumptionAltered brain responsesHedonic brain regionsHippocampal blood flowFurther weight gainFructose ingestionAcyl ghrelinAttenuated suppressionFructose consumptionPerfusion responseBlood flowBrain adaptationBeverage consumptionGreater perfusionPerfusionVentral striatumFunctional MRIWeight gainIngestion