1999
Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells
Endo S, Suzuki M, Sumi M, Nairn A, Morita R, Yamakawa K, Greengard P, Ito M. Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 2467-2472. PMID: 10051666, PMCID: PMC26808, DOI: 10.1073/pnas.96.5.2467.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBrainCerebellumCloning, MolecularCyclic GMP-Dependent Protein KinasesDatabases as TopicExpressed Sequence TagsHumansMolecular Sequence DataNerve Tissue ProteinsPurkinje CellsRabbitsRecombinant ProteinsRNA, MessengerSequence AlignmentSequence Homology, Amino AcidTranscription, GeneticConceptsAmino acid sequenceProtein phosphatase 1G-substrateAcid sequencePhosphatase 1Deduced amino acid sequenceRadiation hybrid panel analysisProtein phosphatase 2APutative phosphorylation sitesCGMP-dependent protein kinaseProtein kinase cascadeProtein phosphatase inhibitorSequence tag databaseSites of phosphorylationVitro translation productsHuman brain libraryCGMP-dependent proteinAcid-soluble proteinsApparent molecular massSDS/PAGEPhosphatase 2AThr-35Kinase cascadePhosphorylation sitesTag database
1996
cGMP-Dependent Protein Kinase in Dorsal Root Ganglion: Relationship with Nitric Oxide Synthase and Nociceptive Neurons
Qian Y, Chao D, Santillano D, Cornwell T, Nairn A, Greengard P, Lincoln T, Bredt D. cGMP-Dependent Protein Kinase in Dorsal Root Ganglion: Relationship with Nitric Oxide Synthase and Nociceptive Neurons. Journal Of Neuroscience 1996, 16: 3130-3138. PMID: 8627352, PMCID: PMC6579134, DOI: 10.1523/jneurosci.16-10-03130.1996.Peer-Reviewed Original ResearchConceptsNeuronal nitric oxide synthaseCGMP-dependent protein kinaseNitric oxide synthaseSensory neuronsProtein kinase ICGMP-dependent protein kinase IOxide synthaseKinase IEmbryonic developmentProtein kinaseG-substrateCalcitonin gene-related polypeptideMedium-diameter DRG neuronsPeripheral nerve axotomyInfluences plasticityDorsal root gangliaCGMP actionRoof plateNerve axotomyDRG neuronsNociceptive neuronsNociceptive processingRoot gangliaSubstance PSpinal cord