2018
Spontaneous rupture of the ascending aorta
Bin Mahmood SU, Ulrich A, Safdar B, Geirsson A, Mangi AA. Spontaneous rupture of the ascending aorta. Journal Of Cardiac Surgery 2018, 33: 107-114. PMID: 29405382, DOI: 10.1111/jocs.13535.Peer-Reviewed Original ResearchConceptsAortic ruptureAortic diameterSpontaneous ruptureHereditary connective tissue disordersHigh-risk patientsConnective tissue disordersOperating room timeRisk of ruptureOperative mortalityChest painMedian doorMost patientsAortic diseaseTissue disordersRoom timePatientsRapid diagnosisSuccessful managementMultidisciplinary approachEmergency protocolsAortaRuptureHypertensionPainEtiology
1999
Lorazepam for the Prevention of Recurrent Seizures Related to Alcohol
D'Onofrio G, Rathlev N, Ulrich A, Fish S, Freedland E. Lorazepam for the Prevention of Recurrent Seizures Related to Alcohol. New England Journal Of Medicine 1999, 340: 915-919. PMID: 10094637, DOI: 10.1056/nejm199903253401203.Peer-Reviewed Original ResearchConceptsPlacebo groupRecurrent seizuresSecond seizureLorazepam groupEmergency departmentNormal salineAlcohol abusePrimary end pointDouble-blind studyChronic alcohol abuseYears of ageIntravenous lorazepamHospital dischargeConsecutive patientsGeneralized seizuresEntry criteriaCommon causePatientsSeizuresEnd pointLorazepamObservation periodSignificant reductionHospitalSaline