2021
Circulating CD4+ TEMRA and CD4+ CD28− T cells and incident diabetes among persons with and without HIV
Bailin SS, Kundu S, Wellons M, Freiberg MS, Doyle MF, Tracy RP, Justice AC, Wanjalla CN, Landay AL, So-Armah K, Mallal S, Kropski JA, Koethe JR. Circulating CD4+ TEMRA and CD4+ CD28− T cells and incident diabetes among persons with and without HIV. AIDS 2021, 36: 501-511. PMID: 34860194, PMCID: PMC8881388, DOI: 10.1097/qad.0000000000003137.Peer-Reviewed Original ResearchConceptsT cell subsetsIncident diabetesT cellsVeterans Aging Cohort StudyPeripheral mononuclear blood cellsIncident diabetes diagnosisPrevalent diabetes mellitusT effector memoryHIV-negative personsHIV-negative individualsTraditional risk factorsAging Cohort StudyCD28- T cellsSenescent T cellsT cell populationsProportional hazards modelMononuclear blood cellsHigh baseline frequencyCytomegalovirus serostatusCirculating CD4Chart reviewCohort studyEffector memoryInflammatory biomarkersMemory CD4
2020
High concordance between chart review adjudication and electronic medical record data to identify prevalent and incident diabetes mellitus among persons with and without HIV
McGinnis KA, Justice AC, Bailin S, Wellons M, Freiberg M, Koethe JR. High concordance between chart review adjudication and electronic medical record data to identify prevalent and incident diabetes mellitus among persons with and without HIV. Pharmacoepidemiology And Drug Safety 2020, 29: 1432-1439. PMID: 33006179, PMCID: PMC7810212, DOI: 10.1002/pds.5111.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationElectronic medical recordsChart reviewVeterans Aging Cohort Study Biomarker CohortElectronic medical record dataPhysician chart reviewHIV-negative participantsIncident diabetes mellitusICD-9 codesMedical record dataIndication of diabetesPhysician adjudicationIncident diabetesDiabetes mellitusHIV infectionBiomarker cohortHIV statusDiabetes prevalenceMedical recordsMedication recordsLaboratory valuesEpidemiologic studiesDiabetes diagnosisDiagnostic criteriaDiabetes
2016
Weight Gain and Incident Diabetes Among HIV-Infected Veterans Initiating Antiretroviral Therapy Compared With Uninfected Individuals
Herrin M, Tate JP, Akgün KM, Butt AA, Crothers K, Freiberg MS, Gibert CL, Leaf DA, Rimland D, Rodriguez-Barradas MC, Ruser CB, Herold KC, Justice AC. Weight Gain and Incident Diabetes Among HIV-Infected Veterans Initiating Antiretroviral Therapy Compared With Uninfected Individuals. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 73: 228-236. PMID: 27171741, PMCID: PMC5023454, DOI: 10.1097/qai.0000000000001071.Peer-Reviewed Original ResearchConceptsRisk of DMVeterans Aging Cohort StudyAntiretroviral therapyAging Cohort StudyDiabetes mellitusBody mass indexUninfected individualsWeight gainART initiationIncident diabetesCohort studyHazard ratioMass indexIncident type 2 diabetes mellitusAvailable body mass indexBaseline body mass indexType 2 diabetes mellitusNational observational studyConfidence intervalsSubstantial weight gainHIV infectionCox regressionPounds of weightObservational studyLow prevalence