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Alfred Kaye, MD, PhD

Assistant Professor of Psychiatry
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About

Titles

Assistant Professor of Psychiatry

Biography

Dr. Kaye is an Assistant Professor of Psychiatry, using a combination of circuit and computational approaches to understand adaptations to the danger in the environment and how those adaptations underlie PTSD. He graduated from the University of California M.D., Ph.D. program, where he used two-photon imaging and computational modeling to understand the organization of visual motion processing. Then, he joined the psychiatry residency at Yale, where he worked in Alex Kwan's lab on using calcium and neurotransmitter imaging to understand how arousal states change after stress, and also developed computational models of PTSD.

The lab will focus on understanding how neuromodulatory circuits reprogram one another to create adaptive responses to traumatic experiences. Underlying this idea is the central problem of developing a mechanistic and functional understanding of stress and anxiety. The lab uses microendoscope and two-photon imaging of calcium and neurotransmitter sensors, large-scale electrophysiology (Neuropixels), computational analysis of behavior (DeepLabCut), and single cell transcriptomics to understand this problem.

Appointments

Education & Training

Research Fellow
Veterans Administration National Center for PTSD (2020)
Non Degree Program
VA National Center for PTSD, Research Fellow (2020)
Resident
Yale University (2018)
Chief Resident
Yale University (2018)
MD
University of California, San Diego (2014)
PhD
University of California, San Diego (2013)

Board Certifications

  • Psychiatry

    Certification Organization
    ABPN
    Original Certification Date
    2021

Research

Overview

Medical Subject Headings (MeSH)

Neurosciences; Norepinephrine; Psychiatry

Research at a Glance

Yale Co-Authors

Frequent collaborators of Alfred Kaye's published research.

Publications

2024

2023

Academic Achievements & Community Involvement

  • activity

    National Science Foundation

  • honor

    Pilot Grant Research Award

  • honor

    Mentored Clinical Scientist Research Career Development Award (K08)

  • honor

    The Seymour L. Lustman Award for Psychiatric Research

  • honor

    NARSD Young Investigator Award