Featured Publications
Excess Cerebrovascular Mortality in the United States During the COVID-19 Pandemic
Sharma R, Kuohn LR, Weinberger DM, Warren JL, Sansing LH, Jasne A, Falcone G, Dhand A, Sheth KN. Excess Cerebrovascular Mortality in the United States During the COVID-19 Pandemic. Stroke 2021, 52: 563-572. PMID: 33430638, PMCID: PMC7834664, DOI: 10.1161/strokeaha.120.031975.Peer-Reviewed Original ResearchConceptsEmergency medical servicesCerebrovascular deathCOVID-19 deathsCerebrovascular mortalityCOVID-19 pandemicStroke-related deathCoronavirus disease 2019 (COVID-19) pandemicFirst COVID-19 deathDisease 2019 pandemicPublic health measuresHealth Statistics dataPoisson regression modelsCumulative COVID-19 deathsAcute strokeStroke deathsVascular pathologyEMS callsMedical careHealth measuresNew York CityMortalityDeathMedical servicesWeeksRegression analysis
2023
Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke
Forman R, Okumu R, Mageid R, Baker A, Neu D, Parker R, Peyravi R, Schindler J, Sansing L, Sheth K, de Havenon A, Jasne A, Narula R, Wira C, Warren J, Sharma R. Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke. Neurology 2023, 102: e207764. PMID: 38165368, PMCID: PMC10834135, DOI: 10.1212/wnl.0000000000207764.Peer-Reviewed Original ResearchMeSH KeywordsEmergency Medical ServicesHospitalsHumansIschemic StrokeSocioeconomic FactorsStrokeUnited StatesConceptsEmergency department arrival timesEmergency medical servicesLate presentationAcute ischemic stroke therapyYale-New Haven HospitalGuidelines-Stroke registryNeighborhood-level socioeconomic factorsPatient-level factorsRetrospective observational studyIschemic stroke therapyMixed-effects logistic regression modelNon-white patientsNon-white raceUnivariate logistic regressionNew Haven HospitalLogistic regression modelsHospital presentationTreatment ineligibilityStroke RegistryAcute strokeHospital arrivalStroke therapyUnivariate analysisObservational studyPatientsChanging Trends in Demographics, Risk Factors, and Clinical Features of Patients With Infective Endocarditis–Related Stroke, 2005–2015
Ridha M, Flaherty M, Aziz Y, Ades L, Alwell K, Khoury J, Woo D, Ferioli S, Adeoye O, Khatri P, De Los Rios La Rosa F, Mistry E, Demel S, Mackey J, Martini S, Coleman E, Jasne A, Slavin S, Walsh K, Star M, Haverbusch M, Madsen T, Broderick J, Kissela B, Kleindorfer D. Changing Trends in Demographics, Risk Factors, and Clinical Features of Patients With Infective Endocarditis–Related Stroke, 2005–2015. Neurology 2023, 100: e1555-e1564. PMID: 36746635, PMCID: PMC10103121, DOI: 10.1212/wnl.0000000000206865.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidDemographyEndocarditisHumansHypertensionRetrospective StudiesRisk FactorsStrokeUnited StatesConceptsRisk factorsOpioid epidemicClinical characteristicsClinical featuresGreater Cincinnati/Northern Kentucky regionStudy periodRetrospective cohort studyRates of hypertensionIntravenous drug useIntravenous drug usersICD-10 codesCochran-Armitage testPerioperative strokeAcute strokeCohort studyDefinite endocarditisDuke criteriaHypertension prevalenceIschemic strokeYounger patientsStroke populationInfective endocarditisAtrial fibrillationEpidemiologic descriptionUnadjusted comparisons
2022
Racial Disparities in Stroke Recurrence
Robinson DJ, Stanton R, Sucharew H, Alwell K, Haverbusch M, De Los Rios La Rosa F, Ferioli S, Coleman E, Jasne A, Mackey J, Star M, Mistry EA, Demel S, Slavin S, Walsh K, Woo D, Kissela B, Kleindorfer DO. Racial Disparities in Stroke Recurrence. Neurology 2022, 99: e2464-e2473. PMID: 36041865, PMCID: PMC9728039, DOI: 10.1212/wnl.0000000000201225.Peer-Reviewed Original ResearchConceptsTraditional stroke risk factorsStroke risk factorsRisk factorsBlack raceRecurrent strokeStroke recurrenceRecurrence rateHigh riskGreater Cincinnati/Northern Kentucky populationBlack individualsStroke/TIA eventsRacial disparitiesStroke recurrence rateMultivariable survival analysisRisk of recurrenceKaplan-Meier estimatesSignificant racial disparitiesTIA eventsIncident strokeSmoking statusVentricular hypertrophyStroke casesRecurrenceSurvival analysisYounger age
2017
Contributors to the Excess Stroke Mortality in Rural Areas in the United States
Howard G, Kleindorfer DO, Cushman M, Long DL, Jasne A, Judd SE, Higginbotham JC, Howard VJ. Contributors to the Excess Stroke Mortality in Rural Areas in the United States. Stroke 2017, 48: 1773-1778. PMID: 28626048, PMCID: PMC5502731, DOI: 10.1161/strokeaha.117.017089.Peer-Reviewed Original ResearchConceptsHigh case fatalityCase fatalityStroke mortalityRisk factorsStroke incidenceSocioeconomic statusTraditional stroke risk factorsIncident stroke riskStroke risk factorsProportional hazards analysisHigher stroke incidenceStroke-free participantsUrban-rural statusHigher stroke mortalityLow socioeconomic statusRural-urban statusExcess stroke mortalityIncident strokeStroke riskREGARDS studyHigh prevalenceHigh incidenceRural areasLogistic regressionSmall rural town