2021
Collateral status reperfusion and outcomes after endovascular therapy: insight from the Endovascular Treatment in Ischemic Stroke (ETIS) Registry
Anadani M, Finitsis S, Clarençon F, Richard S, Marnat G, Bourcier R, Sibon I, Dargazanli C, Arquizan C, Blanc R, Lapergue B, Consoli A, Eugene F, Vannier S, Spelle L, Denier C, Boulanger M, Gauberti M, Liebeskind DS, de Havenon A, Saleme S, Macian F, Rosso C, Naggara O, Turc G, Ozkul-Wermester O, Papagiannaki C, Viguier A, Cognard C, Le Bras A, Evain S, Wolff V, Pop R, Timsit S, Gentric JC, Bourdain F, Veunac L, Maier B, Gory B. Collateral status reperfusion and outcomes after endovascular therapy: insight from the Endovascular Treatment in Ischemic Stroke (ETIS) Registry. Journal Of NeuroInterventional Surgery 2021, 14: 551-557. PMID: 34140288, DOI: 10.1136/neurintsurg-2021-017553.Peer-Reviewed Original ResearchMeSH KeywordsBrain IschemiaCollateral CirculationEndovascular ProceduresHumansIschemic StrokeProspective StudiesRegistriesReperfusionStrokeThrombectomyTreatment OutcomeConceptsIschemic Stroke RegistryPoor collateral groupSuccessful reperfusionCollateral statusEndovascular therapyGood collateralsEVT outcomesStroke RegistryCollateral groupEndovascular treatmentFunctional outcomeFavorable outcomeHigher oddsTherapeutic Neuroradiology/SocietyInterventional Radiology guidelinesPoor collateralsPretreatment angiogramsClinical benefitExcellent outcomesRadiology guidelinesReperfusionLower oddsBetter outcomesSignificant interactionOutcomes
2019
Results From DEFUSE 3
de Havenon A, Mlynash M, Kim-Tenser MA, Lansberg MG, Leslie-Mazwi T, Christensen S, McTaggart RA, Alexander M, Albers G, Broderick J, Marks MP, Heit JJ, Investigators O. Results From DEFUSE 3. Stroke 2019, 50: 632-638. PMID: 30726184, PMCID: PMC6628906, DOI: 10.1161/strokeaha.118.023407.Peer-Reviewed Original ResearchConceptsIschemic core volumeLarge vessel occlusionEndovascular thrombectomyCollateral statusTomography angiographyFunctional independenceDEFUSE 3Poor collateralsLeptomeningeal collateralsStroke patientsVessel occlusionGood collateralsAnterior circulation large vessel occlusionBaseline ischemic core volumeSmall ischemic core volumeAcute ischemic stroke patientsDEFUSE 3 patientsIschemic stroke patientsModified Rankin ScaleStroke-related deathComputed tomography angiographyGood leptomeningeal collateralsTreatment effectsNeurological outcomePrespecified analysis
2017
Association of Collateral Blood Vessels Detected by Arterial Spin Labeling Magnetic Resonance Imaging With Neurological Outcome After Ischemic Stroke
de Havenon A, Haynor DR, Tirschwell DL, Majersik JJ, Smith G, Cohen W, Andre JB. Association of Collateral Blood Vessels Detected by Arterial Spin Labeling Magnetic Resonance Imaging With Neurological Outcome After Ischemic Stroke. JAMA Neurology 2017, 74: 453-458. PMID: 28192548, PMCID: PMC5470363, DOI: 10.1001/jamaneurol.2016.4491.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeArterial spin labeling magnetic resonance imagingCollateral blood vesselsNeurologic outcomeMRS scoreMagnetic resonance imagingNeurological outcomeIschemic strokeScale scoreHealth Stroke Scale scoreResonance imagingMultivariable ordinal logistic regression modelsTertiary academic medical centerBlood vesselsAdmission National InstitutesPremorbid mRS scoreGood neurologic outcomeGood neurological outcomeRetrospective cohort studyStroke Scale scoreRankin Scale scorePresence of collateralsAcademic medical centerLogistic regression modelsOrdinal logistic regression modelsDeterminants of the impact of blood pressure variability on neurological outcome after acute ischaemic stroke
de Havenon A, Bennett A, Stoddard GJ, Smith G, Chung L, O'Donnell S, McNally JS, Tirschwell D, Majersik JJ. Determinants of the impact of blood pressure variability on neurological outcome after acute ischaemic stroke. Stroke And Vascular Neurology 2017, 2: 1. PMID: 28959484, PMCID: PMC5435214, DOI: 10.1136/svn-2016-000057.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBlood PressureBlood Pressure DeterminationCerebral AngiographyCerebrovascular CirculationCollateral CirculationComputed Tomography AngiographyDisability EvaluationFemaleHumansIschemic StrokeMaleMiddle AgedNeuroimagingPatient AdmissionPerfusion ImagingPredictive Value of TestsPrognosisRecovery of FunctionRetrospective StudiesRisk FactorsTime FactorsConceptsBlood pressure variabilityProximal vessel occlusionAcute ischemic strokeIschemic strokeVessel occlusionNeurological outcomeBPV indicesPressure variabilityAcute anterior circulation ischemic strokeAnterior circulation ischemic strokeIntravenous tissue plasminogen activatorGood collateral vesselsIschemic core volumeLarger mismatch volumeWorse neurological outcomeAcute stroke therapySubset of patientsSystolic blood pressureTissue plasminogen activatorLogistic regression modelsOrdinal logistic regression modelsEndovascular thrombectomyIschemic penumbraStroke onsetStroke outcome