2021
Trends in inpatient care for psychiatric disorders in NHS hospitals across England, 1998/99–2019/20: an observational time series analysis
Degli Esposti M, Ziauddeen H, Bowes L, Reeves A, Chekroud A, Humphreys D, Ford T. Trends in inpatient care for psychiatric disorders in NHS hospitals across England, 1998/99–2019/20: an observational time series analysis. Social Psychiatry And Psychiatric Epidemiology 2021, 57: 993-1006. PMID: 34951652, PMCID: PMC8705084, DOI: 10.1007/s00127-021-02215-5.Peer-Reviewed Original ResearchConceptsObservational time series analysisPsychiatric disordersBed daysAdmission ratesHospital activityAge groupsNHS hospitalsBinomial regression modelsNegative binomial regression modelsInpatient psychiatric careMental health needsInpatient hospital activityHospital admissionRegression modelsInpatient carePsychiatric careHealth needsHospitalDisordersCareDepressionAdultsPronounced increaseSame periodChildren
2020
Symptom clusters in adolescent depression and differential response to treatment: a secondary analysis of the Treatment for Adolescents with Depression Study randomised trial
Bondar J, Caye A, Chekroud A, Kieling C. Symptom clusters in adolescent depression and differential response to treatment: a secondary analysis of the Treatment for Adolescents with Depression Study randomised trial. The Lancet Psychiatry 2020, 7: 337-343. PMID: 32199509, DOI: 10.1016/s2215-0366(20)30060-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBayes TheoremChildCognitive Behavioral TherapyCombined Modality TherapyDepressive Disorder, MajorDiagnostic and Statistical Manual of Mental DisordersFemaleFluoxetineHumansMalePsychiatric Status Rating ScalesSelective Serotonin Reuptake InhibitorsTreatment OutcomeUnited StatesConceptsChildren's Depression Rating Scale-RevisedCognitive behavioral therapyCDRS-R scoresSymptom clustersDepression StudyTreatment efficacySecondary analysisMajor depressive disorderDSM-IV diagnosisCo-occurring symptomsSpecific symptom clustersPlacebo groupAcute phaseClinical profileActive treatmentSymptom scoresSleep disturbancesClinical trialsDepressive disorderPill placeboTreatment responseTherapeutic modalitiesSpecific symptomsNew therapiesPhysical complaints
2016
Altered functional brain connectivity in children and young people with opsoclonus–myoclonus syndrome
Chekroud A, Anand G, Yong J, Pike M, Bridge H. Altered functional brain connectivity in children and young people with opsoclonus–myoclonus syndrome. Developmental Medicine & Child Neurology 2016, 59: 98-104. PMID: 27658927, DOI: 10.1111/dmcn.13262.Peer-Reviewed Original ResearchConceptsOpsoclonus-myoclonus syndromeMagnetic resonance imagingMotor cortexOccipito-parietal regionsAltered functional brain connectivityWidespread brain involvementResting-state functional MRI dataComparison groupStructural brain changesCross-sectional studyFunctional brain connectivitySeed-based analysisBrain functional connectivityAge-matched comparison participantsBrain involvementMotor sequelaeBasal gangliaBrain changesPatientsResonance imagingBrain regionsFunctional MRI dataFunctional connectivityVisual networkBrain connectivity
2014
Cerebellar and cortical abnormalities in paediatric opsoclonus‐myoclonus syndrome
Anand G, Bridge H, Rackstraw P, Chekroud A, Yong J, Stagg C, Pike M. Cerebellar and cortical abnormalities in paediatric opsoclonus‐myoclonus syndrome. Developmental Medicine & Child Neurology 2014, 57: 265-272. PMID: 25290446, DOI: 10.1111/dmcn.12594.Peer-Reviewed Original ResearchConceptsOpsoclonus-myoclonus syndromePediatric opsoclonus-myoclonus syndromeGray matter volumeCortical thicknessDiffusion-weighted imagesCerebellar atrophyFlocculonodular lobeMatter volumeMagnetic resonance spectroscopy scansCerebral cortical thicknessTract-based spatial statisticsT1-weighted structural imagesCerebellar gray matter volumeWhole-brain levelWhole-brain analysisWhite matter integrityCerebellar gray matterPersistent symptomatologyClinical outcomesMotor sequelaeChronic phaseCortical abnormalitiesMotor cortexBrain levelsOMS group