2024
Mental healthcare in paediatric epilepsy clinics: implementation by non-mental health professionals
Coughtrey A, Bennett S, Stanick C, Chorpita B, Dalrymple E, Fonagy P, Cross J, Ford T, Heyman I, Moss-Morris R, Jetha P, Myles-Hooton P, Shafran R. Mental healthcare in paediatric epilepsy clinics: implementation by non-mental health professionals. BMJ Paediatrics Open 2024, 8: e002973. PMID: 39557540, PMCID: PMC11574424, DOI: 10.1136/bmjpo-2024-002973.Peer-Reviewed Original ResearchConceptsPaediatric epilepsy clinicsMental health interventionsHealthcare professionalsHealth interventionsImplementation of mental health interventionsEvidence-based mental health interventionsBarriers to effective careNon-mental health professionalsCognitive behavioral therapy interventionPaediatric epilepsy servicesTrained healthcare professionalsEpilepsy clinicMental health experiencesMental health needsMental health disordersBehavioral therapy interventionSupervision packageMental healthcareTherapy interventionsEffective careHealth experiencesHealth professionalsHealth needsHealth disordersMICE protocolTrust under development: The Italian validation of the Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ) for adolescents
Milesi A, Liotti M, Locati F, De Carli P, Speranza A, Campbell C, Fonagy P, Lingiardi V, Parolin L. Trust under development: The Italian validation of the Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ) for adolescents. PLOS ONE 2024, 19: e0307229. PMID: 39186540, PMCID: PMC11346731, DOI: 10.1371/journal.pone.0307229.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildFemaleHumansItalyMaleSelf ReportSurveys and QuestionnairesTrustYoung AdultConceptsSelf-report instrumentEpistemic trustContext of personality disordersConcept of epistemic trustDevelopment of mental disordersPersonality disorderEmotion dysregulationMeasure mentalizingMental disordersPsychological functioningItalian validationMental healthPsychopathologyAdolescent populationInterpersonal trustAdolescentsDisordersResearch contextEmpirical validationHigh schoolItalian adult populationAdult populationMentalQuestionnaireValidityHuman adolescent brain similarity development is different for paralimbic versus neocortical zones
Dorfschmidt L, Váša F, White S, Romero-García R, Kitzbichler M, Alexander-Bloch A, Cieslak M, Mehta K, Satterthwaite T, Consortium T, Bethlehem R, Seidlitz J, Vértes P, Bullmore E, Bullmore E, Dolan R, Goodyer I, Fonagy P, Jones P, Moutoussis M, Hauser T, Neufeld S, Romero-Garcia R, St Clair M, Vértes P, Whitaker K, Inkster B, Prabhu G, Ooi C, Toseeb U, Widmer B, Bhatti J, Villis L, Alrumaithi A, Birt S, Bowler A, Cleridou K, Dadabhoy H, Davies E, Firkins A, Granville S, Harding E, Hopkins A, Isaacs D, King J, Kokorikou D, Maurice C, McIntosh C, Memarzia J, Mills H, O’Donnell C, Pantaleone S, Scott J, Kiddle B, Polek E, Fearon P, Suckling J, van Harmelen A, Kievit R, Chamberlain S, Bethlehem R. Human adolescent brain similarity development is different for paralimbic versus neocortical zones. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2314074121. PMID: 39121162, PMCID: PMC11331068, DOI: 10.1073/pnas.2314074121.Peer-Reviewed Original ResearchConceptsMorphometric similarity networksFunctional connectivityNeocortical areasCortical areasFunctional MRI scansCourse of adolescenceAccelerated longitudinal designMagnetic resonance imagingStructure-function couplingCingulate cortexParalimbic areasInteroceptive functionAssociated with increased strengthIncreased hubnessFMRI networksStructural scansLongitudinal designCortical thinningDevelopment of human brainAdolescent developmentMorphometric similarityHealthy adolescentsAssociated with reduced strengthHuman brainCortexBrief Educational Workshops in Secondary Schools Trial (BESST trial), a school-based cluster randomised controlled trial of the DISCOVER workshop for 16–18-year-olds: recruitment and baseline characteristics
James K, Lisk S, Payne-Cook C, Farishta Z, Farrelly M, Sheikh A, Slusarczyk M, Byford S, Day C, Deighton J, Evans C, Fonagy P, Saunders D, Sclare I, Shearer J, Stallard P, Weaver T, Yarrum J, Carter B, Brown J. Brief Educational Workshops in Secondary Schools Trial (BESST trial), a school-based cluster randomised controlled trial of the DISCOVER workshop for 16–18-year-olds: recruitment and baseline characteristics. Trials 2024, 25: 302. PMID: 38702825, PMCID: PMC11069277, DOI: 10.1186/s13063-024-08116-7.Peer-Reviewed Original ResearchConceptsSchool-based cluster randomised controlled trialWarwick-Edinburgh Mental Wellbeing ScaleCluster randomised controlled trialRandomised controlled trialsSchools TrialEducational workshopsMental Wellbeing ScaleControlled trialsOutcome data collectionSymptoms of depressionEthnic minority groupsSecondary schoolsReduce stigmaBaseline characteristicsPost-randomisationWellbeing ScaleSelf-referralSelf-referredLower wellbeingStudentsDistressed studentsEthnically diverse sampleSchoolWorkshop programmeGeneral wellbeingClinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK
Bennett S, Cross J, Chowdhury K, Ford T, Heyman I, Coughtrey A, Dalrymple E, Byford S, Chorpita B, Fonagy P, Moss-Morris R, Reilly C, Smith J, Stephenson T, Varadkar S, Blackstone J, Quartly H, Hughes T, Lewins A, Moore E, Walji F, Welch A, Whelan E, Zacharia A, D'Oelsnitz A, Shah M, Xu L, Vezyroglou A, Mitchell K, Nizza I, Ganguli P, Shafran R. Clinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK. The Lancet 2024, 403: 1254-1266. PMID: 38461840, DOI: 10.1016/s0140-6736(23)02791-5.Peer-Reviewed Original ResearchConceptsChronic health conditionsMental health disordersUsual careMental health interventionsMental health difficultiesHealth conditionsHealth disordersHealth interventionsHealth difficultiesProgramme Grants for Applied Research programmeNational Institute for Health Research Programme Grants for Applied Research programmeTreating common mental health conditionsMICE groupPrimary mental health disorderYoung peopleMental health comorbiditiesMonths post-randomisationStudy inclusionMental health conditionsEvidence-based psychological treatmentsMental health treatmentMental health assessmentIntellectual disabilityParent-reported StrengthsParticipants aged 3Enhancing emotion regulation with an in situ socially assistive robot among LGBTQ+ youth with self-harm ideation: protocol for a randomised controlled trial
Williams A, Cleare S, Borschmann R, Tench C, Gross J, Hollis C, Chapman-Nisar A, Naeche N, Townsend E, Slovak P, Youth O, Creswell C, Fonagy P, Arseneault L, Lloyd E, De Alcantara Mendes J, Holter C, Jirotka M, Lazar Z, Patalay P, Kelly Y, Kandola A, Sonuga-Barke E, Livingstone S, Kostryka-Allchorne K, Bourgaize J, Stoilova M, O’Connor R, Auer D, Lee S, Jawahar N, Etherson M, Greenhalgh C, Sayal K, Warren J, Wanniarachchi V, Glover K, Stallard P, Hall C, Lucassen M, Merry S, Stasiak K, Babbage C, Khan K, Parker A, Lockwood J, Gregory J, Nielsen E, Vallejos E, Woodcock R, Doherty S, Willingham L. Enhancing emotion regulation with an in situ socially assistive robot among LGBTQ+ youth with self-harm ideation: protocol for a randomised controlled trial. BMJ Open 2024, 14: e079801. PMID: 38195171, PMCID: PMC10806609, DOI: 10.1136/bmjopen-2023-079801.Peer-Reviewed Original ResearchConceptsSelf-harm ideationSelf-harmEmotion dysregulationEmotion regulationRandomised controlled trialsWaitlist controlEnhance emotion regulationExperiences of self-harmSocially assistive robotsSelf-Harm QuestionnaireSelf-harm thoughtsControlled trialsPeer-reviewed open access journalsLGBTQ+ youthPeople’s own viewsAssistive robotsControl participantsIntervention participantsAcceptable interventionSemistructured interviewsLinear mixed modelsPreliminary evidenceEthical approvalKing's College LondonSecondary outcomesBrief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression
Lisk S, James K, Shearer J, Byford S, Stallard P, Deighton J, Saunders D, Yarrum J, Fonagy P, Weaver T, Sclare I, Day C, Evans C, Carter B, Brown J. Brief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression. BMJ Mental Health 2024, 27: e301192. PMID: 39209761, PMCID: PMC11367360, DOI: 10.1136/bmjment-2024-301192.Peer-Reviewed Original ResearchConceptsTreatment-as-usualCluster randomised controlled trialNational Health ServiceElevated symptoms of depressionQuality-adjusted life yearsElevated depressive symptomsSymptoms of depressionRandomised controlled trialsDepressive symptomsSchools TrialElevated symptomsEducational workshopsIntention-to-treatSecondary analysisPersonal Social Services perspectiveControlled trialsMultilevel linear regressionSocial Services perspectiveSchool-based interventionsCost-effectiveIntention-to-treat analysisOutcomes of participantsHealth servicesIncremental cost-effectiveness ratioClinically meaningful effect
2023
Beyond Mentalizing: Epistemic Trust and the Transmission of Culture
Fonagy P, Allison E. Beyond Mentalizing: Epistemic Trust and the Transmission of Culture. The Psychoanalytic Quarterly 2023, 92: 599-640. PMID: 38095858, DOI: 10.1080/00332828.2023.2290023.Peer-Reviewed Original ResearchConceptsEpistemic trustCultural transmissionInterpersonal originsInterpersonal processesPsychological stateExperience of trustMentalizingPsychic changeLifelong impactPsychoanalytic processEssential humanityHuman cultureClinical implicationsTransmission of cultureTrustHuman beingsHelplessnessPsychoanalysis
2011
Get them before they get you: Trust, trustworthiness, and social cognition in boys with and without externalizing behavior problems
Sharp C, Carolyn H, Fonagy P. Get them before they get you: Trust, trustworthiness, and social cognition in boys with and without externalizing behavior problems. Development And Psychopathology 2011, 23: 647-658. PMID: 23786702, DOI: 10.1017/s0954579410000003.Peer-Reviewed Original Research
2004
Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data
Whittington CJ, Kendall T, Fonagy P, Cottrell D, Cotgrove A, Boddington E. Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. The Lancet 2004, 363: 1341-1345. PMID: 15110490, DOI: 10.1016/s0140-6736(04)16043-1.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsRisk-benefit profileFavorable risk-benefit profileSerotonin reuptake inhibitorsPeer-reviewed journalsAdverse eventsReuptake inhibitorsPositive risk-benefit profileUnfavourable risk-benefit profileTrial of sertralineSerious adverse eventsDiscontinuation of treatmentTreatment of depressionTrial of paroxetineDepressive symptom scoresSafety of medicinesClinical guideline developmentUnpublished dataSuicide-related behaviorsUnpublished trialsSymptom scoresFollowing outcomesGuideline developmentIntervention studiesSystematic review