Sex differences in default mode network connectivity in healthy aging adults
Ficek-Tani B, Horien C, Ju S, Xu W, Li N, Lacadie C, Shen X, Scheinost D, Constable T, Fredericks C. Sex differences in default mode network connectivity in healthy aging adults. Cerebral Cortex 2022, 33: 6139-6151. PMID: 36563018, PMCID: PMC10183749, DOI: 10.1093/cercor/bhac491.Peer-Reviewed Original ResearchConceptsDefault mode networkPreclinical Alzheimer's diseaseAlzheimer's diseaseSex differencesBrain connectivity changesDefault mode network connectivityIntrinsic connectivity distributionSeed-based analysisMode network connectivityMedial prefrontal cortexPosterior DMN nodesHealthy aging adultsImpact of sexLifetime riskDMN connectivityWhole brainPosterior cingulateDMN nodesSignificant sex differencesPrefrontal cortexConnectivity changesAging AdultsHealthy participantsDMN functionMode network232-OR: Alterations in Decision-Making Neurocircuits during Hypoglycemia in Patients with T1DM
DEAJON-JACKSON J, RANGEL E, LACADIE C, GREENE A, BELFORT-DEAGUIAR R, CONSTABLE T, ROTHMAN D, HWANG J. 232-OR: Alterations in Decision-Making Neurocircuits during Hypoglycemia in Patients with T1DM. Diabetes 2022, 71 DOI: 10.2337/db22-232-or.Peer-Reviewed Original ResearchDorsal anterior cingulate cortexGroup x Session interactionFunctional connectivityOrbitofrontal cortexControl subjectsNon-diabetic control subjectsHealthy control subjectsState functional connectivityDirect neuronal connectionsRegional brain activityAnterior cingulate cortexSeed-based analysisBOLD-fMRI scanningHyperinsulinemic euglycemicHypoglycemic clampT1DM patientsSession interactionT1DM subjectsGlucose levelsT1DMHypoglycemiaNeurocognitive changesNeuronal connectionsCingulate cortexCognitive function