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Affiliated Faculty

  • James Duncan

    Ebenezer K. Hunt Professor of Radiology and Biomedical Imaging and Professor of Biomedical Engineering; Director of Undergraduate Studies in Biomedical Engineering; Vice Chair, Bioimaging Sciences in the Department of Diagnostic Radiology

    Research Interests
    • Biomedical Engineering
    • Diagnostic Imaging
    • Magnetic Resonance Imaging
    • Radiology
    • Temporal Lobe

    James Duncan, the Ebenezer K. Hunt Professor of Biomedical Engineering, has focused his research and teaching in the areas of biomedical image processing and analysis.

    Duncan, who holds joint appointments in diagnostic radiology and electrical engineering, is the associate chair and director of undergraduate studies in the Department of Biomedical Engineering as well as the vice-chair for bioimaging sciences research in diagnostic radiology. He is particularly interested in the use of model-based mathematical strategies for the analysis of biomedical images. He helped pioneer the use of geometrical models for segmenting deformable (typically anatomical) objects of approximately known shape and for tracking certain forms of non-rigid object motion, and later soft tissue deformation, most notably that of the heart.

    Duncan and his research team performed seminal work starting in 1987 on the use of parameterized global shape models to incorporate a notion of known prior object shape into the segmentation process using a Bayesian reasoning strategy, helping lead the way towards the use of strategies for automatically finding certain known anatomical structure from any of a variety of medical (e.g. computer tomography (CT), magnetic resonance imaging (MRI), ultrasound) and biological (e.g. confocal microscopy) images.

    The strategies he developed have resulted in major advances in bioimaging. He and his research collaborators have applied these strategies to locate the cortical gray matter layer and a variety of co-localized subcortical gray matter structures in the brain as well as to locate the structure near the prostate gland. More recently, Duncan’s team has begun to show that these same techniques will be useful for estimating gray matter-constrained activations from functional MRI data and could help guide the recovery of quantitative biochemical information from MR spectroscopy.

    Beginning in the late 1980s, Duncan also pioneered using shape features on the inner and outer surfaces of the heart wall as material tags for tracking left ventricular motion. This technique was successfully applied to other non-rigid tracking problems in cell biology and became the basis for a variety of efforts internationally. Duncan and his research team used this strategy for more sophisticated analysis in echocardiography. The team’s approach is now recognized in the medical-image-analysis community as among the first to incorporate true physical models into image analysis strategies and has helped develop a more general area of physical/biomechanical model-based re covery of both structural and functional information from biomedical images. Duncan’s laboratory has also developed initial forms of these techniques to estimate brain shift during epilepsy neurosurgery and guide fractionated prostate radiotherapy, among other uses. His work has resulted in three U.S. patents.

    Duncan is the principal investigator of major research funded by the National Institutes of Health. Before coming to Yale in 1983, he worked for Hughes Aircraft Company. He holds a B.S.E.E. from Lafayette College, an M.S. from the University of California at Los Angeles and a Ph.D. from the University of Southern California.

    Duncan is a fellow of the Institute of Electrical and Electronics Engineers (IEEE) and the American Institute for Medical and Biological Engineering. He is president of the International Society for Medical Image Computing and Computer Assisted Intervention and is a member of the American Association for Artificial Intelligence and the I.E.E.E. Computer Society, among other professional organizations.

  • Jeffrey Pollak

    Robert I. White, Jr. Professor of Radiology and Biomedical Imaging; Director, Yale Hereditary Hemorrhagic Telangiectasia Program; Director, Vascular and Interventional Radiology Fellowship Program

    Research Interests
    • Arteriovenous Fistula
    • Arteriovenous Malformations
    • Carcinoma, Hepatocellular
    • Telangiectasia, Hereditary Hemorrhagic
    • Radiography, Interventional
    • Portasystemic Shunt, Transjugular Intrahepatic
    • Vascular Malformations
    • Ablation Techniques
    Clinical Interests
    • Angiography
    • Arterio-Arterial Fistula
    • Arteriovenous Fistula
    • Arteriovenous Malformations
    • Blood Vessels
    • Bronchial Arteries
    • Carcinoma, Renal Cell
    • Embolization, Therapeutic
    • Femoral Vein
    • Hepatic Artery
    • Hepatic Veins
    • Carcinoma, Hepatocellular
    • Hypertension, Renal
    • Hypertension, Renovascular
    • Iliac Vein
    • Klippel-Trenaunay-Weber Syndrome
    • Leiomyoma
    • Liver
    • Liver Cirrhosis
    • Popliteal Vein
    • Portal System
    • Portal Vein
    • Pulmonary Artery
    • Subclavian Vein
    • Superior Vena Cava Syndrome
    • Telangiectasia, Hereditary Hemorrhagic
    • Varicocele
    • Vena Cava, Inferior
    • Vena Cava, Superior
    • Venae Cavae
    • Stents
    • Brachiocephalic Veins
    • Vascular Fistula
    • Vena Cava Filters
    • Chemoembolization, Therapeutic
    • Angioplasty
    • Aneurysm, False
    • Portasystemic Shunt, Transjugular Intrahepatic
    • Vascular Malformations
    • Ablation Techniques
    • Uterine Artery Embolization
    • May-Thurner Syndrome
    • Mesenteric Ischemia

    Dr. Pollak went to medical school at the Columbia University College of Physicians & Surgeons and subsequently did his Diagnostic Radiology residency at the Columbia-Presbyterian Medical Center. His fellowship in Vascular & Interventional Radiology was at the Hospital of the University of Pennsylvania. He then joined the Yale University School of Medicine Department of Radiology and Biomedical Imaging in the section of V&IR and served as the section chief and director of the fellowship program in this sub-specialty for over two decades. While active in all aspects of vascular & interventional radiology, his current major interests are embolotherapy (embolization), including for acquired and congenital vascular abnormalities and malformations (other than in the brain), fibroids, and malignancies, as well as other minimally invasive treatments for tumors, including local ablation. In addition, he is an expert in vascular procedures in the liver, such as intrahepatic portosystemic shunts and venous procedures, such as inferior vena cava filters.

    Dr. Pollak is the current director of the multidisciplinary Yale Hereditary Hemorrhagic Telangiectasia Program, which was started as the first of its kind in the world in the early 1990s. As such, he has extensive experience in the evaluation and management of patients with this genetic disorder, with particular expertise in embolization of pulmonary arteriovenous malformations, which frequently occur in this population. Dr. Pollak is also the co-director of the Yale Pulmonary Embolism Response Team, a multidisciplinary group of physicians interested in the advancement of the management of patients with this condition, especially those with more severe manifestations.

  • Todd Schlachter

    Assistant Professor

    Research Interests
    • Abscess
    • Bile Ducts, Intrahepatic
    • Cholangiography
    • Cholangitis
    • Cholestasis, Intrahepatic
    • Computer Systems
    • Education
    • Fatty Liver
    • Carcinoma, Hepatocellular
    • Hepatorenal Syndrome
    • Image Processing, Computer-Assisted
    • Lithotripsy
    • Liver Abscess
    • Liver Circulation
    • Liver Cirrhosis
    • Liver Cirrhosis, Alcoholic
    • Liver Cirrhosis, Biliary
    • Radiographic Image Enhancement
    • Radiographic Image Interpretation, Computer-Assisted
    • Radiography, Interventional
    • Hepatoblastoma
    • Cholangiocarcinoma
    • Hepatopulmonary Syndrome
    • Ablation Techniques
    Clinical Interests
    • Bile Ducts
    • Biliary Tract
    • Biliary Tract Neoplasms
    • Gallbladder
    • Gastrointestinal Neoplasms
    • Liver
    • Liver Neoplasms
    • Pancreas
    • Pancreatic Neoplasms
    • Superior Vena Cava Syndrome
    • Varicocele
    • Vascular Diseases
    • Venous Insufficiency

    Dr. Schlachter is an Assistant Professor of Radiology and Biomedical Imaging at the Yale School of Medicine.

    Dr. Schlachter's research interests include: Liver Cancer and diseases involving the liver.

    Dr. Schlachter completed his surgical intern year at the University of Pennsylvania School of Medicine and his Radiology Residency from the University of Connecticut School of Medicine. After finishing his Interventional Radiology fellowship at Johns Hopkins School of Medicine in 2012, he was hired as an Attending where he focused on treating a wide range of vascular diseases including liver cancer. Dr. Schlachter is committed to working together to determine the most effective treatments for his patients.

  • Jeffrey Weinreb

    Professor of Radiology and Biomedical Imaging; Director, MRI Services; Chief, MRI Service

    Research Interests
    • Liver

    After graduating Phi Beta Kappa from the Massachusetts Institute of Technology, Dr. Weinreb received his medical degree from the Mount Sinai School of Medicine. He has held faculty positions at University of Texas Southwestern Medical School, Columbia College for Physicians and Surgeons, and New York University School of Medicine, where he was Director of MRI for 15 years and led a group that pioneered the development of Body MRI, Breast MRI, and MRA. Yale has been his home since 2002.
    Dr. Weinreb is currently Professor of Radiology and Biomedical Imaging at the Yale School of Medicine and Chief of MRI at Yale-New Haven Hospital. He is a leading authority on MRI contrast agents, MRI safety, and the use of MRI for the abdomen (focusing on the liver), and pelvis (focusing on the prostate). A noted educator and lecturer, he has presented more than 900 invited lectures and has been a frequent Visiting Professor throughout the world. Dr. Weinreb has authored/co-authored more than 200 published manuscripts and 3 textbooks, and he has been on the editorial boards of numerous medical journals. As Chairman of the American College of Radiology Commission on Quality and Safety, Dr. Weinreb spearheaded efforts to improve the quality of medical imaging in the USA. Recently, he led an international effort to develop PI-RADS v2 (Prostate Imaging Reporting and Data System Version 2) to standardize the acquisition, interpretation, and reporting of prostate MRI, and the manuscript was recognized as the Best Clinical Research Paper published in European Urology for 2016. He has served as President of the SCBT/MR, President of the New York Roentgen Society, and Vice President of the ACR, and he currently chairs ACR RADS Steering Committee. He is the recipient of the 2017 ACR Gold Medal Award.