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Faculty & Researchers

  • Assistant Professor Adjunct, Radiology & Biomedical Imaging

    Dr. Lin received the B.S. degree from Rensselaer Polytechnic Institute and the Ph.D. degree from Duke University, all in biomedical engineering. He is currently the Director for Clinical Research in North America for Visage Imaging and is stationed at Yale-New Haven Hospital where he oversees, coordinates, drives and directs research collaborations with high profile academic hospitals in North America to develop new solutions for diagnostic image analysis and guidance that improve clinical and operational outcomes while reducing cost of care. This includes activities in Artificial Intelligence (AI) and Machine Learning (ML) in the Radiology enterprise diagnostic imaging solutions space. Dr. Lin identifies opportunities for academic-industry research partnerships, and acts as the liaison between Visage Imaging researchers and clinical collaborators to translate ideas to prototype for clinical validation, with the goal of technology transfer to product. A highlight is Ming coordinated the clinical data curation and ground-truth annotation for building a fully automatic breast density AI classifier that provides an ACR BI-RADS Atlas 5th Edition breast density category to aid radiologists in the assessment of breast tissue composition from full field digital mammography and digital breast tomosynthesis systems and drove the clinical validation with Yale radiologists and Visage developers that led to transfer to product and regulatory approvals in 21 months. Notably, this was the first for a major PACS vendor to offer a self-developed, FDA-cleared AI algorithm natively into their PACS: Visage Breast Density, K201411, 510(k) clearance, January 2021, Health Canada Licensed, October 2020, Australian TGA approval, July 2020, CE Mark Cleared, May 2020.

    Dr. Lin also is directly involved in research to develop better ways to treat patients with liver cancer using transcatheter arterial chemoembolization (TACE) and in this context, he is also the chief engineer and operations manager of the Yale Interventional Oncology Research Lab. Dr. Lin is the Principle Investigator (PI) on two NIH R01 grants to improve the diagnosis, treatment, and response assessment after transcatheter arterial chemoembolization for patients with liver cancer. Dr. Lin is the inventor of 3D quantification TACE therapy response tool (qEASL) and in collaboration with clinical partners, validated, and showed clinical relevance (ability to predict patient survival) that led to transfer to commercial product (FDA 510(k) cleared December 2016 - Multi-Modality Tumor Tracking (MMTT) application). Prior to Visage Imaging, Dr. Lin was the Philips research site manager and senior researcher stationed onsite at Yale where he managed the research portfolio and partnership Philips has with Yale.

  • Assistant Professor; Resident in Radiology and Biomedical Imaging

    Dr. Chapiro joined the Department of Radiology and Biomedical Imaging as a research scientist and interventional radiology resident from Berlin, Germany. After graduating from the University of Leipzig and upon completion of his research thesis at the Justus-Liebig University in Giessen with summa cum laude, he served as a postdoctoral research fellow in interventional oncology at The Johns Hopkins Hospital and then as radiology resident at the Department of Radiology, Charité University Hospital in Berlin.

    Dr. Chapiro’s research focuses on developing new quantitative imaging biomarkers for the diagnosis, characterization, and therapeutic management of liver cancer. His translational research portfolio includes the development of novel embolic agents as well as the application of artificial intelligence solutions for the management of liver cancer. His basic research interest mainly focuses on developing new tools to characterize the tumor microenvironment and the immune system in the setting of loco-regional, image-guided therapies of liver cancer.

    Creating innovative and clinically applicable imaging solutions for liver cancer with advanced molecular imaging, image post-processing and machine learning approaches and translating them to clinical practice has been his central mission for the past decade. He authored and co-authored >100 original research articles, reviews and book chapters and gave more than 70 talks and invited lectures within the last five years. His research has also resulted in several patents, 510(k)-approved medical products and significant grant support from federal, foundational and industry sources. He is an active research mentor to more than 30 undergraduate, medical and graduate students as well as peers both at Yale and other national and international institutions. Being an active contributor, journal-, abstract- and grant reviewer in several professional societies (RSNA, SIR and SIO), he is also committed to education and the mission of disseminating research data and scientific knowledge. Dr. Chapiro consults the Editorial Board of the Journal of Hepatology, is a member of the American College of Radiology Liver Imaging Reporting and Data System (LI-RADS) Steering Committee, he additionally serves on the Society of Interventional Oncology Research Committee and is the incoming Chair of the Annual Meeting Program Planning Committee for the Subspecialty of Interventional Radiology at the Annual Radiological Society of North America meeting 2021-2023. He is the co-initiator of the "Rising Star" Student Exchange Program in collaboration with the Charité University Hospital in Berlin and co-directs the Yale Interventional Oncology Research Laboratory. Dr. Chapiro is the Associate Director of the Clinical and Translational Core of the Yale Liver Center. 

  • Research Associate, Radiology

    Eliot Funai graduated from the University of Maryland, Baltimore County, and previously worked at Johns Hopkins University before coming to Yale. His work as a clinical research coordinator is to develop and oversee the management and execution of clinical trials, primarily concerning locoregional therapies for treating liver cancers. His experience is with investigator initiated studies, industry and NIH-funded trials, and cooperative group studies.

  • Clinical Fellow

    Edvin Isufi is a native of Albania and received his medical degree from University of Medicine of Tirana in 2001. He completed his 4 years of residency training in Radiology at the "Mother Teresa" University Hospital of Tirana in 2008. His focus during the residency was interventional radiology. His plan for the future is getting into radiology residency and certified from the American Board of Radiology. Dr. Isufi joined the Interventional Oncology Research Laboratory as a Visiting Research Scientist, participating in different clinical trials, primarily concerning trans-catheter loco-regional therapies.

  • Simon Iseke joined the Department of Radiology and Biomedical Imaging at Yale in October 2019 as a Postgraduate Associate within the “Rising Star” Research Exchange Program between the Charité University Hospital Berlin, Germany and the Yale School of Medicine. Simon is a 3rd-year medical student at the University Hospital Rostock and received a travel grant from the Rolf W. Günther Foundation for Radiological Sciences.
  • Postgraduate Associate

    Jessica received her Master’s degree in Biomedical Sciences with a focus on cancer development and immune responses from Radboud Universiteit in the Netherlands. She concluded her program at the Department of Immunobiology at Yale through the Radboud University Medical Center Study Fund and travel grant for traineeship abroad. She recently joined the Department of Radiology and Biomedical Imaging as a Postgraduate Fellow, where she is working with animal models for molecular characterization of the tumor microenvironment to loco-reginal therapies in liver cancer from an imaging perspective. 

      She received her B.S in Biomedical Sciences from the Universidade Estadual de Santa Cruz, Brazil, with further research experience from Harvard School of Public Health, USA, and Mcgill University, Canada, through the Science Without Borders Scholarship Program

  • Hospital Resident

    Fabian is the Chief Resident in Interventional Radiology at Yale New Haven Hospital. He joined Yale in 2016 after having completed medical school at Ludwig Maximilians University (LMU) Munich and his surgical intern year at Cornell Presbyterian Hospital in New York. Fabian is a co-founder of Road2IR. This collaborative effort of Muhimbili University of Health and Allied Sciences (MUHAS) in Tanzania, together with Yale, Emory and other institutions in North America has the goal of making interventional radiology more accessible in East Africa. The project was awarded with an RSNA R&E Foundation Derek Harwood-Nash International Education Scholar Grant in 2020. Fabian is also active in the Yale Interventional Oncology lab, where he has worked on evaluation of a novel imaging technique to visualize tumor hypoxia and acidity noninvasively in a rabbit liver tumor model after transarterial chemoembolization. 

  • Hospital Resident; Integrated IR/DR Residency, Radiology & Biomedical Imaging

    Brian Letzen received his M.D. degree from the Yale School of Medicine, where he continues as an interventional/diagnostic radiology resident. He graduated with a master’s degree in biomedical engineering from the Johns Hopkins University and with a bachelor’s degree in electrical engineering from the University of Florida. In the past, he has worked in engineering at GE Healthcare and Oak Ridge National Laboratory. His overall research interests involve clinical, translational, and basic science innovations to provide cancer patients with the least invasive approaches to diagnosis, treatment, and surveillance - incorporating "big data" and artificial intelligence. He received a RSNA Research Resident Grant to develop a novel liver diagnosis tool using deep machine learning techniques. Additionally, he is currently investigating innovations in intra-operative cone beam CT for transarterial chemoembolization of liver tumors.

  • Medical Student

    Mansur Ghani is a third year medical student at Yale School of Medicine. Since joining the group in 2015, Mansur's work has involved predicting response to treatment of HCC to intra-arterial therapy and investigating staging biomarkers for colorectal cancer metastases to the liver. He currently holds a BS in Molecular Biophysics and Biochemistry from Yale College, and plans to apply for residency programs in interventional radiology.
  • Moritz Gross joined the Yale Interventional Oncology Research Lab in October 2019 as a Postgraduate Associate within the “Rising Star” Research Exchange Program in collaboration with the Charité University Berlin, where he is a 4th-year medical student.

    His current research at the Yale Interventional Oncology Research Lab focuses on Machine Learning.

    For his travel to Yale, he received a travel grant from the Rolf W. Günther Foundation for Radiological Sciences.

    Moreover, he is part of the Noninvasive Imaging Heisenberg Research Group of Prof. Dr. Marc Dewey at Charité in Berlin, where he is researching on noninvasive cardiovascular imaging research.

  • Medical Student

    Medical Student at Yale School of Medicine. Studied Neurobiology, Physiology, and Behavior in his home state at the University of California, Davis. Research experience in interventional radiology, diagnostic radiology, and addiction medicine. Currently investigating the effects of intra-arterial embolic therapies such as chemoembolization, drug-eluting bead embolization, and radioembolization in the treatment of hepatocellular carcinoma and metastatic liver tumors. Other ongoing research includes investigation of the role of multiparametric MRI in the diagnosis of prostate cancer.