Yale Interventional Oncology Research Lab Publications

2023

Experimental VX2 Rabbit Liver Tumor Model in Carbon Tetrachloride-Induced Cirrhosis of the Liver.Santana JG, Shewarega A, Nam D, Kahl V, Madoff DC, Zhang X, Chapiro J. J Vasc Interv Radiol. 2023 Mar; 2022 Dec 5. PMID: 36473611.
MR Imaging-Based In Vivo Macrophage Imaging to Monitor Immune Response after Radiofrequency Ablation of the Liver.Santana JG, Petukhova-Greenstein A, Gross M, Hyder F, Pekurovsky V, Gottwald LA, Boustani A, Walsh JJ, Kucukkaya AS, Malpani R, Madoff DC, Goldberg SN, Ahmed M, Joshi N, Coman D, Chapiro J. J Vasc Interv Radiol. 2023 Mar; 2022 Nov 21. PMID: 36423815.
Comparing 3D, 2.5D, and 2D Approaches to Brain Image Auto-Segmentation.Avesta A, Hossain S, Lin M, Aboian M, Krumholz HM, Aneja S. Bioengineering (Basel). 2023 Feb 1; 2023 Feb 1. PMID: 36829675.
Transpleural Systemic Artery-to-Pulmonary Artery Shunts: A Potential Mimicker of Pulmonary Arteriovenous Malformations.Fish FA, Chan SM, Pollak J, Schlachter T. J Vasc Interv Radiol. 2023 Feb; 2022 Oct 23. PMID: 36283590.
Defining textbook outcome for selective internal radiation therapy of hepatocellular carcinoma: an international expert study.Gregory J, Tselikas L, Allimant C, de Baere T, Bargellini I, Bell J, Bilbao JI, Bouvier A, Chapiro J, Chiesa C, Decaens T, Denys A, Duran R, Edeline J, Garin E, Ghelfi J, Helmberger T, Irani F, Lam M, Lewandowski R, Liu D, Loffroy R, Madoff DC, Mastier C, Salem R, Sangro B, Sze D, Vilgrain V, Vouche M, Guiu B, Ronot M. Eur J Nucl Med Mol Imaging. 2023 Feb; 2022 Oct 25. PMID: 36282299.
Machine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study.Iseke S, Zeevi T, Kucukkaya AS, Raju R, Gross M, Haider SP, Petukhova-Greenstein A, Kuhn TN, Lin M, Nowak M, Cooper K, Thomas E, Weber MA, Madoff DC, Staib L, Batra R, Chapiro J. AJR Am J Roentgenol. 2023 Feb; 2022 Aug 17. PMID: 35975886.
DuDoSS: Deep-learning-based dual-domain sinogram synthesis from sparsely sampled projections of cardiac SPECT.Chen X, Zhou B, Xie H, Miao T, Liu H, Holler W, Lin M, Miller EJ, Carson RE, Sinusas AJ, Liu C. Med Phys. 2023 Jan; 2022 Sep 28. PMID: 36048541.

2022

Conventional vs. Drug-Eluting Beads Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma-A Propensity Score Weighted Comparison of Efficacy and Safety.Savic LJ, Chen E, Nezami N, Murali N, Hamm CA, Wang C, Lin M, Schlachter T, Hong K, Georgiades C, Chapiro J, Laage Gaupp FM. Cancers (Basel). 2022 Nov 27; 2022 Nov 27. PMID: 36497329.
Clinical implementation of artificial intelligence in neuroradiology with development of a novel workflow-efficient picture archiving and communication system-based automated brain tumor segmentation and radiomic feature extraction.Aboian M, Bousabarah K, Kazarian E, Zeevi T, Holler W, Merkaj S, Cassinelli Petersen G, Bahar R, Subramanian H, Sunku P, Schrickel E, Bhawnani J, Zawalich M, Mahajan A, Malhotra A, Payabvash S, Tocino I, Lin M, Westerhoff M. Front Neurosci. 2022; 2022 Oct 13. PMID: 36312024.
Analysis of Tumor Burden as a Biomarker for Patient Survival with Neuroendocrine Tumor Liver Metastases Undergoing Intra-Arterial Therapies: A Single-Center Retrospective Analysis.Miszczuk M, Chapiro J, Do Minh D, van Breugel JMM, Smolka S, Rexha I, Tegel B, Lin M, Savic LJ, Hong K, Georgiades C, Nezami N. Cardiovasc Intervent Radiol. 2022 Oct; 2022 Aug 8. PMID: 35941241.
Research Priorities in Percutaneous Image- and Endoscopy-Guided Interventions for Biliary and Gallbladder Diseases: Proceedings from the Society of Interventional Radiology Foundation Multidisciplinary Research Consensus Panel.Riaz A, Trivedi P, Aadam AA, Katariya N, Matsuoka L, Malik A, Gunn AJ, Vezeridis A, Sarwar A, Schlachter T, Harmath C, Srinivasa R, Abi-Jaoudeh N, Singh H. J Vasc Interv Radiol. 2022 Oct; 2022 Jul 7. PMID: 35809805.
Proceedings from the Society of Interventional Radiology Foundation Research Consensus Panel on Artificial Intelligence in Interventional Radiology: From Code to Bedside.Chapiro J, Allen B, Abajian A, Wood B, Kothary N, Daye D, Bai H, Sedrakyan A, Diamond M, Simonyan V, McLennan G, Abi-Jaoudeh N, Pua B. J Vasc Interv Radiol. 2022 Sep; 2022 Jul 19. PMID: 35871021.
Response assessment methods for patients with hepatic metastasis from rare tumor primaries undergoing transarterial chemoembolization.Adam LC, Savic LJ, Chapiro J, Letzen B, Lin M, Georgiades C, Hong KK, Nezami N. Clin Imaging. 2022 Sep; 2022 Jun 26. PMID: 35777239.
Cryoablation of Venous Malformations: A Systematic Review.Fish A, Moushey A, Chan SM, Staib L, Marino A, Schlachter T. J Vasc Interv Radiol. 2022 Aug; 2022 Apr 22. PMID: 35469956.
Real-time PACS-integrated longitudinal brain metastasis tracking tool provides comprehensive assessment of treatment response to radiosurgery.Cassinelli Petersen G, Bousabarah K, Verma T, von Reppert M, Jekel L, Gordem A, Jang B, Merkaj S, Abi Fadel S, Owens R, Omuro A, Chiang V, Ikuta I, Lin M, Aboian MS. Neurooncol Adv. 2022 Jan-Dec; 2022 Jul 26. PMID: 36043121.
Three-Dimensional Quantitative Tumor Response and Survival Analysis of Hepatocellular Carcinoma Patients Who Failed Initial Transarterial Chemoembolization: Repeat or Switch Treatment?Zhao Y, Haroun RR, Sahu S, Schernthaner RE, Smolka S, Lin MD, Hong KK, Georgiades C, Duran R. Cancers (Basel). 2022 Jul 25; 2022 Jul 25. PMID: 35892874.
Intraarterial Therapies for the Management of Hepatocellular Carcinoma.Garg T, Shrigiriwar A, Habibollahi P, Cristescu M, Liddell RP, Chapiro J, Inglis P, Camacho JC, Nezami N. Cancers (Basel). 2022 Jul 10; 2022 Jul 10. PMID: 35884412.
Safety and feasibility of single use cholecystoscopy for guiding laser or mechanical cholelithotripsy, and mechanical cholelithotomy.Nezami N, Latich I, Chockalingam A, Arici M, Lee J, Perez Lozada JCL, Schlachter T. Diagn Interv Radiol. 2022 Jul. PMID: 35950279.
MR Imaging Biomarkers for the Prediction of Outcome after Radiofrequency Ablation of Hepatocellular Carcinoma: Qualitative and Quantitative Assessments of the Liver Imaging Reporting and Data System and Radiomic Features.Petukhova-Greenstein A, Zeevi T, Yang J, Chai N, DiDomenico P, Deng Y, Ciarleglio M, Haider SP, Onyiuke I, Malpani R, Lin M, Kucukkaya AS, Gottwald LA, Gebauer B, Revzin M, Onofrey J, Staib L, Gunabushanam G, Taddei T, Chapiro J. J Vasc Interv Radiol. 2022 Jul; 2022 Apr 20. PMID: 35460887.
Translating artificial intelligence from code to bedside: The road towards AI-driven predictive biomarkers for immunotherapy of hepatocellular carcinoma.Chapiro J. J Hepatol. 2022 Jul; 2022 Apr 10. PMID: 35417743.
Optimization of the BCLC Staging System for Locoregional Therapy for Hepatocellular Carcinoma by Using Quantitative Tumor Burden Imaging Biomarkers at MRI.Borde T, Nezami N, Laage Gaupp F, Savic LJ, Taddei T, Jaffe A, Strazzabosco M, Lin M, Duran R, Georgiades C, Hong K, Chapiro J. Radiology. 2022 Jul; 2022 Apr 12. PMID: 35412368.
Impact of Chemoembolic Regimen on Immune Cell Recruitment and Immune Checkpoint Marker Expression following Transcatheter Arterial Chemoembolization in a VX2 Rabbit Liver Tumor Model.Berz AM, Santana JG, Iseke S, Gross M, Pekurovsky V, Laage Gaupp F, Savic LJ, Borde T, Gottwald LA, Boustani AM, Gebauer B, Lin M, Zhang X, Schlachter T, Madoff DC, Chapiro J. J Vasc Interv Radiol. 2022 Jul; 2022 Mar 26. PMID: 35346859.
Direct and indirect strategies of deep-learning-based attenuation correction for general purpose and dedicated cardiac SPECT.Chen X, Zhou B, Xie H, Shi L, Liu H, Holler W, Lin M, Liu YH, Miller EJ, Sinusas AJ, Liu C. Eur J Nucl Med Mol Imaging. 2022 Jul; 2022 Feb 16. PMID: 35169887.
Identifying clinically applicable machine learning algorithms for glioma segmentation: recent advances and discoveries.Tillmanns N, Lum AE, Cassinelli G, Merkaj S, Verma T, Zeevi T, Staib L, Subramanian H, Bahar RC, Brim W, Lost J, Jekel L, Brackett A, Payabvash S, Ikuta I, Lin M, Bousabarah K, Johnson MH, Cui J, Malhotra A, Omuro A, Turowski B, Aboian MS. Neurooncol Adv. 2022 Jan-Dec; 2022 Jun 14. PMID: 36071926.
Machine Learning Tools for Image-Based Glioma Grading and the Quality of Their Reporting: Challenges and Opportunities.Merkaj S, Bahar RC, Zeevi T, Lin M, Ikuta I, Bousabarah K, Cassinelli Petersen GI, Staib L, Payabvash S, Mongan JT, Cha S, Aboian MS. Cancers (Basel). 2022 May 25; 2022 May 25. PMID: 35681603.
Machine Learning Models for Classifying High- and Low-Grade Gliomas: A Systematic Review and Quality of Reporting Analysis.Bahar RC, Merkaj S, Cassinelli Petersen GI, Tillmanns N, Subramanian H, Brim WR, Zeevi T, Staib L, Kazarian E, Lin M, Bousabarah K, Huttner AJ, Pala A, Payabvash S, Ivanidze J, Cui J, Malhotra A, Aboian MS. Front Oncol. 2022; 2022 Apr 22. PMID: 35530302.
Artificial intelligence in liver diseases: Improving diagnostics, prognostics and response prediction.Nam D, Chapiro J, Paradis V, Seraphin TP, Kather JN. JHEP Rep. 2022 Apr; 2022 Feb 2. PMID: 35243281.
What's Needed to Bridge the Gap Between US FDA Clearance and Real-world Use of AI Algorithms.Lin M. Acad Radiol. 2022 Apr; 2021 Nov 20. PMID: 34794879.
Comparison of metabolic and immunologic responses to transarterial chemoembolization with different chemoembolic regimens in a rabbit VX2 liver tumor model.Doemel LA, Santana JG, Savic LJ, Gaupp FML, Borde T, Petukhova-Greenstein A, Kucukkaya AS, Schobert IT, Hamm CA, Gebauer B, Walsh JJ, Rexha I, Hyder F, Lin M, Madoff DC, Schlachter T, Chapiro J, Coman D. Eur Radiol. 2022 Apr; 2021 Oct 31. PMID: 34718844.
Machine Learning Applications for Differentiation of Glioma from Brain Metastasis-A Systematic Review.Jekel L, Brim WR, von Reppert M, Staib L, Cassinelli Petersen G, Merkaj S, Subramanian H, Zeevi T, Payabvash S, Bousabarah K, Lin M, Cui J, Brackett A, Mahajan A, Omuro A, Johnson MH, Chiang VL, Malhotra A, Scheffler B, Aboian MS. Cancers (Basel). 2022 Mar 8; 2022 Mar 8. PMID: 35326526.
Quantitative Automated Segmentation of Lipiodol Deposits on Cone-Beam CT Imaging Acquired during Transarterial Chemoembolization for Liver Tumors: A Deep Learning Approach.Malpani R, Petty CW, Yang J, Bhatt N, Zeevi T, Chockalingam V, Raju R, Petukhova-Greenstein A, Santana JG, Schlachter TR, Madoff DC, Chapiro J, Duncan J, Lin M. J Vasc Interv Radiol. 2022 Mar; 2021 Dec 16. PMID: 34923098.

2021

Improved performance and consistency of deep learning 3D liver segmentation with heterogeneous cancer stages in magnetic resonance imaging.Gross M, Spektor M, Jaffe A, Kucukkaya AS, Iseke S, Haider SP, Strazzabosco M, Chapiro J, Onofrey JA. PLoS One. 2021; 2021 Dec 1. PMID: 34852007.
Consensus Guidelines for the Definition of Time-to-Event End Points in Image-guided Tumor Ablation: Results of the SIO and DATECAN Initiative.Puijk RS, Ahmed M, Adam A, Arai Y, Arellano R, de Baère T, Bale R, Bellera C, Binkert CA, Brace CL, Breen DJ, Brountzos E, Callstrom MR, Carrafiello G, Chapiro J, de Cobelli F, Coupé VMH, Crocetti L, Denys A, Dupuy DE, Erinjeri JP, Filippiadis D, Gangi A, Gervais DA, Gillams AR, Greene T, Guiu B, Helmberger T, Iezzi R, Kang TW, Kelekis A, Kim HS, Kröncke T, Kwan S, Lee MW, Lee FT, Lee EW Jr, Liang P, Lissenberg-Witte BI, Lu DS, Madoff DC, Mauri G, Meloni MF, Morgan R, Nadolski G, Narayanan G, Newton I, Nikolic B, Orsi F, Pereira PL, Pua U, Rhim H, Ricke J, Rilling W, Salem R, Scheffer HJ, Sofocleous CT, Solbiati LA, Solomon SB, Soulen MC, Sze D, Uberoi R, Vogl TJ, Wang DS, Wood BJ, Goldberg SN, Meijerink MR. Radiology. 2021 Dec; 2021 Sep 28. PMID: 34581627.
Identifying enhancement-based staging markers on baseline MRI in patients with colorectal cancer liver metastases undergoing intra-arterial tumor therapy.Ghani MA, Fereydooni A, Chen E, Letzen B, Laage-Gaupp F, Nezami N, Deng Y, Gan G, Thakur V, Lin M, Papademetris X, Schernthaner RE, Huber S, Chapiro J, Hong K, Georgiades C. Eur Radiol. 2021 Dec; 2021 Jun 1. PMID: 34061209.
Longitudinal Analysis of the Effect of Repeated Transarterial Chemoembolization for Liver Cancer on Portal Venous Pressure.Frangakis C, Sohn JH, Bas A, Chapiro J, Schernthaner RE, Lin M, Hamilton JP, Pawlik TM, Hong K, Duran R. Front Oncol. 2021; 2021 Nov 5. PMID: 34804911.
Machine Learning-Based Surveillance Strategy after Complete Ablation of Initially Recurrent Hepatocellular Carcinoma: Worth the Risk?Nam D, Chapiro J. J Vasc Interv Radiol. 2021 Nov. PMID: 34717834.
Lipiodol Deposition and Washout in Primary and Metastatic Liver Tumors After Chemoembolization.Nezami N, VAN Breugel JMM, Konstantinidis M, Chapiro J, Savic LJ, Miszczuk MA, Rexha I, Lin M, Hong K, Georgiades C. In Vivo. 2021 Nov-Dec. PMID: 34697157.
Incidence of Spontaneous Pulmonary AVM Rupture in HHT Patients.Fish A, Henderson K, Moushey A, Pollak J, Schlachter T. J Clin Med. 2021 Oct 14; 2021 Oct 14. PMID: 34682838.
Lipiodol as an intra-procedural imaging biomarker for liver tumor response to transarterial chemoembolization: Post-hoc analysis of a prospective clinical trial.Letzen BS, Malpani R, Miszczuk M, de Ruiter QMB, Petty CW, Rexha I, Nezami N, Laage-Gaupp F, Lin M, Schlachter TR, Chapiro J. Clin Imaging. 2021 Oct; 2021 May 18. PMID: 34022765.
How COVID-19 kick-started online learning in medical education-The DigiMed study.Stoehr F, Müller L, Brady A, Trilla A, Mähringer-Kunz A, Hahn F, Düber C, Becker N, Wörns MA, Chapiro J, Hinrichs JB, Akata D, Ellmann S, Huisman M, Koff D, Brinkmann S, Bamberg F, Zimmermann O, Traikova NI, Marquardt JU, Chang DH, Rengier F, Auer TA, Emrich T, Muehler F, Schmidberger H, Baeßler B, Dos Santos DP, Kloeckner R. PLoS One. 2021; 2021 Sep 21. PMID: 34547031.
Hepatic Radiofrequency Ablation: Monitoring of Ablation-Induced Macrophage Recruitment in the Periablational Rim Using SPION-Enhanced Macrophage-Specific Magnetic Resonance Imaging.Collettini F, Brangsch J, Reimann C, Chapiro J, Savic LJ, Buchholz R, Keller S, Hamm B, Goldberg SN, Makowski MR. Invest Radiol. 2021 Sep 1. PMID: 33787536.
Quantitative volumetric assessment of baseline enhancing tumor volume as an imaging biomarker predicts overall survival in patients with glioblastoma.Auer TA, Della Seta M, Collettini F, Chapiro J, Zschaeck S, Ghadjar P, Badakhshi H, Florange J, Hamm B, Budach V, Kaul D. Acta Radiol. 2021 Sep; 2020 Sep 16. PMID: 32938221.
Thermal ablation alone vs thermal ablation combined with transarterial chemoembolization for patients with small (<3 cm) hepatocellular carcinoma.Chai NX, Chapiro J, Petukhova A, Gross M, Kucukkaya A, Raju R, Zeevi T, Elbanan M, Lin M, Perez-Lozada JC, Schlachter T, Strazzabosco M, Pollak JS, Madoff DC. Clin Imaging. 2021 Aug; 2021 Feb 11. PMID: 33592550.
Anatomy-guided multimodal registration by learning segmentation without ground truth: Application to intraprocedural CBCT/MR liver segmentation and registration.Zhou B, Augenfeld Z, Chapiro J, Zhou SK, Liu C, Duncan JS. Med Image Anal. 2021 Jul; 2021 Mar 21. PMID: 33823397.
Cost-Effectiveness of Imaging Tumor Response Criteria in Hepatocellular Cancer After Transarterial Chemoembolization.Wu X, Chapiro J, Malhotra A. J Am Coll Radiol. 2021 Jul; 2021 Jan 20. PMID: 33484726.
Deep learning-assisted differentiation of pathologically proven atypical and typical hepatocellular carcinoma (HCC) versus non-HCC on contrast-enhanced MRI of the liver.Oestmann PM, Wang CJ, Savic LJ, Hamm CA, Stark S, Schobert I, Gebauer B, Schlachter T, Lin M, Weinreb JC, Batra R, Mulligan D, Zhang X, Duncan JS, Chapiro J. Eur Radiol. 2021 Jul; 2021 Jan 6. PMID: 33409782.
Reliable prediction of survival in advanced-stage hepatocellular carcinoma treated with sorafenib: comparing 1D and 3D quantitative tumor response criteria on MRI.Doemel LA, Chapiro J, Laage Gaupp F, Savic LJ, Kucukkaya AS, Petukhova A, Tefera J, Zeevi T, Lin M, Schlachter T, Jaffe A, Strazzabosco M, Patel T, Stein SM. Eur Radiol. 2021 May; 2020 Oct 30. PMID: 33123796.
Prospective study of Lipiodol distribution as an imaging marker for doxorubicin pharmacokinetics during conventional transarterial chemoembolization of liver malignancies.Savic LJ, Chapiro J, Funai E, Bousabarah K, Schobert IT, Isufi E, Geschwind JH, Stark S, He P, Rudek MA, Perez Lozada JC, Ayyagari R, Pollak J, Schlachter T. Eur Radiol. 2021 May; 2020 Oct 15. PMID: 33063185.
Role of 3D quantitative tumor analysis for predicting overall survival after conventional chemoembolization of intrahepatic cholangiocarcinoma.Rexha I, Laage-Gaupp F, Chapiro J, Miszczuk MA, van Breugel JMM, Lin M, Konstantinidis M, Duran R, Gebauer B, Georgiades C, Hong K, Nezami N. Sci Rep. 2021 Apr 29; 2021 Apr 29. PMID: 33927226.
Elastin-specific MRI of extracellular matrix-remodelling following hepatic radiofrequency-ablation in a VX2 liver tumor model.Collettini F, Reimann C, Brangsch J, Chapiro J, Savic LJ, Onthank DC, Robinson SP, Karst U, Buchholz R, Keller S, Hamm B, Goldberg SN, Makowski MR. Sci Rep. 2021 Mar 25; 2021 Mar 25. PMID: 33767303.
Use of Artificial Intelligence in Non-Oncologic Interventional Radiology: Current State and Future Directions.Malpani R, Petty CW, Bhatt N, Staib LH, Chapiro J. Dig Dis Interv. 2021; 2021 Jul 17. PMID: 35005333.
Comparison of Drug-Eluting Embolics versus Conventional Transarterial Chemoembolization for the Treatment of Patients with Unresectable Hepatocellular Carcinoma: A Cost-Effectiveness Analysis.Wu X, Chapiro J, Malhotra A, Kothary N. J Vasc Interv Radiol. 2021 Jan; 2020 Nov 5. PMID: 33160827.
Automated detection and delineation of hepatocellular carcinoma on multiphasic contrast-enhanced MRI using deep learning.Bousabarah K, Letzen B, Tefera J, Savic L, Schobert I, Schlachter T, Staib LH, Kocher M, Chapiro J, Lin M. Abdom Radiol (NY). 2021 Jan; 2020 Jun 4. PMID: 32500237.
Fibronodular hepatocellular carcinoma-a new variant of liver cancer: clinical, pathological and radiological correlation.Tefera J, Revzin M, Chapiro J, Savic LJ, Mulligan D, Batra R, Taddei T, Jain D, Zhang X. J Clin Pathol. 2021 Jan; 2020 May 19. PMID: 32430483.

2020

Therapy of Intermediate-Stage Hepatocellular Carcinoma: Current Evidence and Clinical Practice.Chai NX, Chapiro J. Semin Intervent Radiol. 2020 Dec; 2020 Dec 11. PMID: 33328701.
Quantification of contrast-uptake as imaging biomarker for disease progression of renal cell carcinoma after tumor ablation.Tegel BR, Huber S, Savic LJ, Lin M, Gebauer B, Pollak J, Chapiro J. Acta Radiol. 2020 Dec; 2020 Mar 26. PMID: 32216452.
Automated feature quantification of Lipiodol as imaging biomarker to predict therapeutic efficacy of conventional transarterial chemoembolization of liver cancer.Stark S, Wang C, Savic LJ, Letzen B, Schobert I, Miszczuk M, Murali N, Oestmann P, Gebauer B, Lin M, Duncan J, Schlachter T, Chapiro J. Sci Rep. 2020 Oct 22; 2020 Oct 22. PMID: 33093524.
Idarubicin-Loaded ONCOZENE Drug-Eluting Bead Chemoembolization in a Rabbit Liver Tumor Model: Investigating Safety, Therapeutic Efficacy, and Effects on Tumor Microenvironment.Borde T, Laage Gaupp F, Geschwind JF, Savic LJ, Miszczuk M, Rexha I, Adam L, Walsh JJ, Huber S, Duncan JS, Peters DC, Sinusas A, Schlachter T, Gebauer B, Hyder F, Coman D, van Breugel JMM, Chapiro J. J Vasc Interv Radiol. 2020 Oct; 2020 Jul 17. PMID: 32684417.
Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as predictors of tumor response in hepatocellular carcinoma after DEB-TACE.Schobert IT, Savic LJ, Chapiro J, Bousabarah K, Chen E, Laage-Gaupp F, Tefera J, Nezami N, Lin M, Pollak J, Schlachter T. Eur Radiol. 2020 Oct; 2020 May 19. PMID: 32424595.
Predicting Infiltrative Hepatocellular Carcinoma Patient Outcome Post-TACE: MR Bias Field Correction Effect on 3D-quantitative Image Analysis.Liu C, Smolka S, Papademetris X, Minh DD, Gan G, Deng Y, Lin M, Chapiro J, Wang X, Georgiades C, Hong K. J Clin Transl Hepatol. 2020 Sep 28; 2020 Aug 18. PMID: 33083252.
Molecular MRI of the Immuno-Metabolic Interplay in a Rabbit Liver Tumor Model: A Biomarker for Resistance Mechanisms in Tumor-targeted Therapy?Savic LJ, Doemel LA, Schobert IT, Montgomery RR, Joshi N, Walsh JJ, Santana J, Pekurovsky V, Zhang X, Lin M, Adam L, Boustani A, Duncan J, Leng L, Bucala RJ, Goldberg SN, Hyder F, Coman D, Chapiro J. Radiology. 2020 Sep; 2020 Jul 7. PMID: 32633675.
Quantitative MRI for Assessment of Treatment Outcomes in a Rabbit VX2 Hepatic Tumor Model.Keller S, Chapiro J, Brangsch J, Reimann C, Collettini F, Sack I, Savic LJ, Hamm B, Goldberg SN, Makowski M. J Magn Reson Imaging. 2020 Sep; 2019 Nov 12. PMID: 31713973.
Extracellular pH mapping of liver cancer on a clinical 3T MRI scanner.Coman D, Peters DC, Walsh JJ, Savic LJ, Huber S, Sinusas AJ, Lin M, Chapiro J, Constable RT, Rothman DL, Duncan JS, Hyder F. Magn Reson Med. 2020 May; 2019 Nov 5. PMID: 31691371.
Supervised Machine Learning in Oncology: A Clinician's Guide.Murali N, Kucukkaya A, Petukhova A, Onofrey J, Chapiro J. Dig Dis Interv. 2020 Mar. PMID: 32869010.
Lipiodol as an Imaging Biomarker of Tumor Response After Conventional Transarterial Chemoembolization: Prospective Clinical Validation in Patients with Primary and Secondary Liver Cancer.Miszczuk MA, Chapiro J, Geschwind JH, Thakur V, Nezami N, Laage-Gaupp F, Kulon M, van Breugel JMM, Fereydooni A, Lin M, Savic LJ, Tegel B, Wahlin T, Funai E, Schlachter T. Transl Oncol. 2020 Mar; 2020 Feb 22. PMID: 32092672.
Comparing HCC arterial tumour vascularisation on baseline imaging and after lipiodol cTACE: how do estimations of enhancing tumour volumes differ on contrast-enhanced MR and CT?Luedemann WM, Geisel D, Gebauer B, Schnapauff D, Chapiro J, Wieners G, Steffen I, Kahn J. Eur Radiol. 2020 Mar; 2019 Dec 6. PMID: 31811428.
Prostatic Artery Embolization in Nonindex Benign Prostatic Hyperplasia Patients: Single-center Outcomes for Urinary Retention and Gross Prostatic Hematuria.Ayyagari R, Powell T, Staib L, Chapiro J, Perez-Lozada JC, Bhatia S, Chai T, Schoenberger S, Devito R. Urology. 2020 Feb; 2019 Nov 14. PMID: 31734349.
Molecular Imaging of Extracellular Tumor pH to Reveal Effects of Locoregional Therapy on Liver Cancer Microenvironment.Savic LJ, Schobert IT, Peters D, Walsh JJ, Laage-Gaupp FM, Hamm CA, Tritz N, Doemel LA, Lin M, Sinusas A, Schlachter T, Duncan JS, Hyder F, Coman D, Chapiro J. Clin Cancer Res. 2020 Jan 15; 2019 Oct 3. PMID: 31582517.
Accelerating the Translation of Artificial Intelligence From Ideas to Routine Clinical Workflow.Lin M. Acad Radiol. 2020 Jan. PMID: 31818377.
Prostatic Artery Embolization Using 100-300-μm Trisacryl Gelatin Microspheres to Treat Lower Urinary Tract Symptoms Attributable to Benign Prostatic Hyperplasia: A Single-Center Outcomes Analysis with Medium-Term Follow-up.Ayyagari R, Powell T, Staib L, Chapiro J, Raja A, Bhatia S, Chai T, Schoenberger S, Devito R. J Vasc Interv Radiol. 2020 Jan; 2019 Nov 23. PMID: 31771896.

2019

Interventional oncology: aiming globally to be the 4th pillar of cancer care.Madoff DC, Chapiro J, Pua U. Chin Clin Oncol. 2019 Dec. PMID: 31968980.
Cholangiolithiasis postliver transplantation: Successful treatment utilizing percutaneous transhepatic cholangioscopy and laser lithotripsy.Nezami N, Benchetrit L, Latich I, Schlachter T. Radiol Case Rep. 2019 Dec; 2019 Oct 8. PMID: 31641393.
A 3D quantitative imaging biomarker in pre-treatment MRI predicts overall survival after stereotactic radiation therapy of patients with a singular brain metastasis.Della Seta M, Collettini F, Chapiro J, Angelidis A, Engeling F, Hamm B, Kaul D. Acta Radiol. 2019 Nov; 2019 Mar 6. PMID: 30841703.
Domain-Agnostic Learning with Anatomy-Consistent Embedding for Cross-Modality Liver Segmentation.Yang J, Dvornek NC, Zhang F, Zhuang J, Chapiro J, Lin M, Duncan JS. IEEE Int Conf Comput Vis Workshops. 2019 Oct; 2020 Mar 5. PMID: 34676308.
Unsupervised Domain Adaptation via Disentangled Representations: Application to Cross-Modality Liver Segmentation.Yang J, Dvornek NC, Zhang F, Chapiro J, Lin M, Duncan JS. Med Image Comput Comput Assist Interv. 2019 Oct; 2019 Oct 10. PMID: 32377643.
Fluorodeoxyglucose PET for Monitoring Response to Embolotherapy (Transarterial Chemoembolization) in Primary and Metastatic Liver Tumors.Schobert I, Chapiro J, Pucar D, Saperstein L, Savic LJ. PET Clin. 2019 Oct; 2019 Aug 7. PMID: 31472741.
From Code to Bedside: Introducing Predictive Intelligence to Interventional Oncology.Chapiro J, Duncan JS. Radiol Artif Intell. 2019 Sep 25; 2019 Sep 25. PMID: 32076661.
Case-Control Comparison of Conventional End-Hole versus Balloon-Occlusion Microcatheter Prostatic Artery Embolization for Treatment of Symptomatic Benign Prostatic Hyperplasia.Ayyagari R, Powell T, Staib L, Chapiro J, Schoenberger S, Devito R, Pollak J. J Vasc Interv Radiol. 2019 Sep; 2019 Jul 30. PMID: 31375451.
Quantitative Imaging Biomarkers for (90)Y Distribution on Bremsstrahlung SPECT After Resin-Based Radioembolization.Schobert I, Chapiro J, Nezami N, Hamm CA, Gebauer B, Lin M, Pollak J, Saperstein L, Schlachter T, Savic LJ. J Nucl Med. 2019 Aug; 2019 Jan 17. PMID: 30655331.
Deep learning for liver tumor diagnosis part II: convolutional neural network interpretation using radiologic imaging features.Wang CJ, Hamm CA, Savic LJ, Ferrante M, Schobert I, Schlachter T, Lin M, Weinreb JC, Duncan JS, Chapiro J, Letzen B. Eur Radiol. 2019 Jul; 2019 May 15. PMID: 31093705.
Deep learning for liver tumor diagnosis part I: development of a convolutional neural network classifier for multi-phasic MRI.Hamm CA, Wang CJ, Savic LJ, Ferrante M, Schobert I, Schlachter T, Lin M, Duncan JS, Weinreb JC, Chapiro J, Letzen B. Eur Radiol. 2019 Jul; 2019 Apr 23. PMID: 31016442.
Immunotherapy and the Interventional Oncologist: Challenges and Opportunities-A Society of Interventional Oncology White Paper.Erinjeri JP, Fine GC, Adema GJ, Ahmed M, Chapiro J, den Brok M, Duran R, Hunt SJ, Johnson DT, Ricke J, Sze DY, Toskich BB, Wood BJ, Woodrum D, Goldberg SN. Radiology. 2019 Jul; 2019 Apr 23. PMID: 31012818.
Theranostic application of lipiodol for transarterial chemoembolization in a VX2 rabbit liver tumor model.van Breugel JMM, Geschwind JF, Mirpour S, Savic LJ, Zhang X, Duran R, Lin M, Miszczuk M, Liapi E, Chapiro J. Theranostics. 2019; 2019 May 27. PMID: 31281506.
The Role of Artificial Intelligence in Interventional Oncology: A Primer.Letzen B, Wang CJ, Chapiro J. J Vasc Interv Radiol. 2019 Jan; 2018 Dec 7. PMID: 30528289.

2018

Irinotecan-Eluting 75-150-μm Embolics Lobar Chemoembolization in Patients with Colorectal Cancer Liver Metastases: A Prospective Single-Center Phase I Study.Fereydooni A, Letzen B, Ghani MA, Miszczuk MA, Huber S, Chapiro J, Schlachter T, Geschwind JF, Georgiades C. J Vasc Interv Radiol. 2018 Dec; 2018 Oct 15. PMID: 30337148.
Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma.Abajian A, Murali N, Savic LJ, Laage-Gaupp FM, Nezami N, Duncan JS, Schlachter T, Lin M, Geschwind JF, Chapiro J. J Vis Exp. 2018 Oct 10; 2018 Oct 10. PMID: 30371657.
Liver Tissue Classification Using an Auto-context-based Deep Neural Network with a Multi-phase Training Framework.Zhang F, Yang J, Nezami N, Laage-Gaupp F, Chapiro J, De Lin M, Duncan J. Patch Based Tech Med Imaging (2018). 2018 Sep; 2018 Sep 15. PMID: 32432233.
Clinical Experience with Real-Time 3-D Guidance Based on C-Arm-Acquired Cone-Beam CT (CBCT) in Transjugular Intrahepatic Portosystemic Stent Shunt (TIPSS) Placement.Böning G, Lüdemann WM, Chapiro J, Jonczyk M, Hamm B, Günther RW, Gebauer B, Streitparth F. Cardiovasc Intervent Radiol. 2018 Jul; 2018 Mar 14. PMID: 29541837.
Predicting Treatment Response to Intra-arterial Therapies for Hepatocellular Carcinoma with the Use of Supervised Machine Learning-An Artificial Intelligence Concept.Abajian A, Murali N, Savic LJ, Laage-Gaupp FM, Nezami N, Duncan JS, Schlachter T, Lin M, Geschwind JF, Chapiro J. J Vasc Interv Radiol. 2018 Jun; 2018 Mar 14. PMID: 29548875.
Sensitivity and Reproducibility of Automated Feeding Artery Detection Software during Transarterial Chemoembolization of Hepatocellular Carcinoma.Chiaradia M, Izamis ML, Radaelli A, Prevoo W, Maleux G, Schlachter T, Mayer J, Luciani A, Kobeiter H, Tacher V. J Vasc Interv Radiol. 2018 Mar; 2018 Feb 3. PMID: 29402612.
Characteristics of a New X-Ray Imaging System for Interventional Procedures: Improved Image Quality and Reduced Radiation Dose.Schernthaner RE, Haroun RR, Nguyen S, Duran R, Sohn JH, Sahu S, Chapiro J, Zhao Y, Radaelli A, van der Bom IM, Mauti M, Hong K, Geschwind JH, Lin M. Cardiovasc Intervent Radiol. 2018 Mar; 2017 Oct 31. PMID: 29090348.
Which Criteria Applied in Multi-Phasic CT Can Predict Early Tumor Response in Patients with Hepatocellular Carcinoma Treated Using Conventional TACE: RECIST, mRECIST, EASL or qEASL?Zhao Y, Duran R, Bai W, Sahu S, Wang W, Kabus S, Lin M, Han G, Geschwind JF. Cardiovasc Intervent Radiol. 2018 Mar; 2017 Oct 30. PMID: 29086058.
C-Arm Cone Beam CT for Intraprocedural Image Fusion and 3D Guidance in Portal Vein Embolization (PVE).Lüdemann WM, Böning G, Chapiro J, Jonczyk M, Geisel D, Schnapauff D, Wieners G, Schmelzle M, Chopra S, Günther RW, Gebauer B, Streitparth F. Cardiovasc Intervent Radiol. 2018 Mar; 2017 Sep 5. PMID: 28875339.
Science to Practice: Decrypting the Enigma of Ablation-induced Off-Target Effects-Is Network Pathway Analysis the Final Piece of the Puzzle?Murali N, Laage-Gaupp FM, Chapiro J, Geschwind JF. Radiology. 2018 Feb. PMID: 29356646.

2017

Intra-arterial therapy of neuroendocrine tumour liver metastases: comparing conventional TACE, drug-eluting beads TACE and yttrium-90 radioembolisation as treatment options using a propensity score analysis model.Do Minh D, Chapiro J, Gorodetski B, Huang Q, Liu C, Smolka S, Savic LJ, Wainstejn D, Lin M, Schlachter T, Gebauer B, Geschwind JF. Eur Radiol. 2017 Dec; 2017 Jul 4. PMID: 28677067.
Science to Practice: Molecular-targeted Drug Delivery in Combination with Radiofrequency Ablation of Liver Cancer: A Magic Bullet?Adam LC, Murali N, Chapiro J, Geschwind JF. Radiology. 2017 Nov. PMID: 29045226.
The impact of antiangiogenic therapy combined with Transarterial Chemoembolization on enhancement based quantitative tumor response assessment in patients with hepatocellular carcinoma.Smolka S, Chapiro J, Manzano W, Treilhard J, Reiner E, Deng Y, Zhao Y, Hamm B, Duncan JS, Gebauer B, Lin M, Geschwind JF. Clin Imaging. 2017 Nov-Dec; 2017 Jun 7. PMID: 28668723.
Liver tissue classification in patients with hepatocellular carcinoma by fusing structured and rotationally invariant context representation.Treilhard J, Smolka S, Staib L, Chapiro J, Lin M, Shakirin G, Duncan J. Med Image Comput Comput Assist Interv. 2017 Sep; 2017 Sep 4. PMID: 29900427.
Science to Practice: Killing Dormant Cells-Is Targeting Autophagy the Key to Complete Tumor Response in Transarterial Chemoembolization?Savic LJ, Chapiro J, Geschwind JF. Radiology. 2017 Jun. PMID: 28514219.
Imaging Biomarkers of Tumor Response in Neuroendocrine Liver Metastases Treated with Transarterial Chemoembolization: Can Enhancing Tumor Burden of the Whole Liver Help Predict Patient Survival?Sahu S, Schernthaner R, Ardon R, Chapiro J, Zhao Y, Sohn JH, Fleckenstein F, Lin M, Geschwind JF, Duran R. Radiology. 2017 Jun; 2016 Nov 10. PMID: 27831830.