Publications

• Clostridioides difficile ferrosome organelles combat nutritional immunity.Pi H, Sun R, McBride JR, Kruse ARS, Gibson-Corley KN, Krystofiak ES, Nicholson MR, Spraggins JM, Zhou Q, Skaar EP. Nature. 2023 Nov; 2023 Nov 15. PMID: 37968387.
• Bacterial hydrophilins promote pathogen desiccation tolerance.Green ER, Fakhoury JN, Monteith AJ, Pi H, Giedroc DP, Skaar EP. Cell Host Microbe. 2022 Jul 13; 2022 Apr 11. PMID: 35413266.
• An RNA-binding protein acts as a major post-transcriptional modulator in Bacillus anthracis.Pi H, Weiss A, Laut CL, Grunenwald CM, Lin HK, Yi XI, Stauff DL, Skaar EP. Nat Commun. 2022 Mar 21; 2022 Mar 21. PMID: 35314695.
• A Central Role for Magnesium Homeostasis during Adaptation to Osmotic Stress.Wendel BM, Pi H, Krüger L, Herzberg C, Stülke J, Helmann JD. mBio. 2022 Feb 22; 2022 Feb 15. PMID: 35164567.
• DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis.Laut CL, Leasure CS, Pi H, Carlin SM, Chu ML, Hillebrand GH, Lin HK, Yi XI, Stauff DL, Skaar EP. Infect Immun. 2022 Jan 25; 2021 Nov 8. PMID: 34748369.
• Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis.Pi H, Chu ML, Ivan SJ, Latario CJ, Toth AM, Carlin SM, Hillebrand GH, Lin HK, Reppart JD, Stauff DL, Skaar EP. PLoS Pathog. 2020 Dec; 2020 Dec 23. PMID: 33362282.
• Dysregulation of Magnesium Transport Protects Bacillus subtilis against Manganese and Cobalt Intoxication.Pi H, Wendel BM, Helmann JD. J Bacteriol. 2020 Mar 11; 2020 Mar 11. PMID: 31964700.
• Genome-Wide Characterization of the Fur Regulatory Network Reveals a Link between Catechol Degradation and Bacillibactin Metabolism in Bacillus subtilis.Pi H, Helmann JD. mBio. 2018 Oct 30; 2018 Oct 30. PMID: 30377275.
• Antagonism of Two Plant-Growth Promoting Bacillus velezensis Isolates Against Ralstonia solanacearum and Fusarium oxysporum.Cao Y, Pi H, Chandrangsu P, Li Y, Wang Y, Zhou H, Xiong H, Helmann JD, Cai Y. Sci Rep. 2018 Mar 12; 2018 Mar 12. PMID: 29531357.
• Sequential induction of Fur-regulated genes in response to iron limitation in Bacillus subtilis.Pi H, Helmann JD. Proc Natl Acad Sci U S A. 2017 Nov 28; 2017 Nov 13. PMID: 29133393.
• Ferrous iron efflux systems in bacteria.Pi H, Helmann JD. Metallomics. 2017 Jul 19. PMID: 28604884.
• The Listeria monocytogenes Fur-regulated virulence protein FrvA is an Fe(II) efflux P1B4 -type ATPase.Pi H, Patel SJ, Argüello JM, Helmann JD. Mol Microbiol. 2016 Jun; 2016 Apr 14. PMID: 26946370.
• Structure-activity relationship for the oxadiazole class of antibiotics.Spink E, Ding D, Peng Z, Boudreau MA, Leemans E, Lastochkin E, Song W, Lichtenwalter K, O'Daniel PI, Testero SA, Pi H, Schroeder VA, Wolter WR, Antunes NT, Suckow MA, Vakulenko S, Chang M, Mobashery S. J Med Chem. 2015 Feb 12; 2015 Jan 30. PMID: 25590813.
• Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.Bouley R, Kumarasiri M, Peng Z, Otero LH, Song W, Suckow MA, Schroeder VA, Wolter WR, Lastochkin E, Antunes NT, Pi H, Vakulenko S, Hermoso JA, Chang M, Mobashery S. J Am Chem Soc. 2015 Feb 11; 2015 Feb 2. PMID: 25629446.
• Structure and cell wall cleavage by modular lytic transglycosylase MltC of Escherichia coli.Artola-Recolons C, Lee M, Bernardo-García N, Blázquez B, Hesek D, Bartual SG, Mahasenan KV, Lastochkin E, Pi H, Boggess B, Meindl K, Usón I, Fisher JF, Mobashery S, Hermoso JA. ACS Chem Biol. 2014 Sep 19; 2014 Jul 10. PMID: 24988330.
• Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity.O'Daniel PI, Peng Z, Pi H, Testero SA, Ding D, Spink E, Leemans E, Boudreau MA, Yamaguchi T, Schroeder VA, Wolter WR, Llarrull LI, Song W, Lastochkin E, Kumarasiri M, Antunes NT, Espahbodi M, Lichtenwalter K, Suckow MA, Vakulenko S, Mobashery S, Chang M. J Am Chem Soc. 2014 Mar 5; 2014 Feb 21. PMID: 24517363.
• A chemical biological strategy to facilitate diabetic wound healing.Gooyit M, Peng Z, Wolter WR, Pi H, Ding D, Hesek D, Lee M, Boggess B, Champion MM, Suckow MA, Mobashery S, Chang M. ACS Chem Biol. 2014 Jan 17; 2013 Sep 26. PMID: 24053680.
• Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall.Lee M, Hesek D, Llarrull LI, Lastochkin E, Pi H, Boggess B, Mobashery S. J Am Chem Soc. 2013 Mar 6; 2013 Feb 21. PMID: 23421439.
• Role of catecholate siderophores in gram-negative bacterial colonization of the mouse gut.Pi H, Jones SA, Mercer LE, Meador JP, Caughron JE, Jordan L, Newton SM, Conway T, Klebba PE. PLoS One. 2012; 2012 Nov 29. PMID: 23209633.
• A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes.McLaughlin HP, Xiao Q, Rea RB, Pi H, Casey PG, Darby T, Charbit A, Sleator RD, Joyce SA, Cowart RE, Hill C, Klebba PE, Gahan CG. PLoS One. 2012; 2012 Feb 21. PMID: 22363518.
• Sortase independent and dependent systems for acquisition of haem and haemoglobin in Listeria monocytogenes.Xiao Q, Jiang X, Moore KJ, Shao Y, Pi H, Dubail I, Charbit A, Newton SM, Klebba PE. Mol Microbiol. 2011 Jun; 2011 May 6. PMID: 21545655.
• Direct measurements of the outer membrane stage of ferric enterobactin transport: postuptake binding.Newton SM, Trinh V, Pi H, Klebba PE. J Biol Chem. 2010 Jun 4; 2010 Mar 24. PMID: 20335169.