2014
Membrane adhesion dictates Golgi stacking and cisternal morphology
Lee I, Tiwari N, Dunlop MH, Graham M, Liu X, Rothman JE. Membrane adhesion dictates Golgi stacking and cisternal morphology. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 1849-1854. PMID: 24449908, PMCID: PMC3918774, DOI: 10.1073/pnas.1323895111.Peer-Reviewed Original ResearchConceptsFK506-binding protein (FKBP) domainsGolgi cisternaeGolgi matrix proteinsClass of proteinsCisternal morphologyCisternal maturationProtein domainsGolgi membranesGolgi stacksRegulatory proteinsGolgiMatrix proteinsMembrane adhesionMembrane transportProtein 55Adhesive processHeLa cellsAdhesive proteinsProteinGolginsCargo transportAncient formCisternaeQuantitative electron microscopyMitochondria
2009
Increased anxiety‐like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2
Blundell J, Tabuchi K, Bolliger M, Blaiss C, Brose N, Liu X, Südhof T, Powell C. Increased anxiety‐like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2. Genes Brain & Behavior 2009, 8: 114-126. PMID: 19016888, PMCID: PMC2648807, DOI: 10.1111/j.1601-183x.2008.00455.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnxietyBehavior, AnimalBlotting, WesternCell Adhesion Molecules, NeuronalElectroshockGene DeletionInterpersonal RelationsLearningMaleMembrane ProteinsMiceMice, KnockoutMicroscopy, ElectronMotor ActivityNerve Tissue ProteinsPainPain MeasurementPostural BalanceSocial BehaviorSynapsesConceptsInhibitory synaptic functionInhibitory synaptic punctaAnxiety-like behaviorSynaptic functionInhibitory synapsesSynaptic punctaMutant miceInhibitory synapse numbersPostsynaptic cell adhesion moleculesBehavioral phenotypesSocial interaction deficitsSymmetric synapsesPain sensitivitySynapse numberCell adhesion moleculeNeuroligin-2Global deletionMiceAdhesion moleculesInteraction deficitsMarked increaseSynapsesBehavioral changesSynapse propertiesPuncta