2023
Characterization of long COVID temporal sub-phenotypes by distributed representation learning from electronic health record data: a cohort study
Dagliati A, Strasser Z, Abad Z, Klann J, Wagholikar K, Mesa R, Visweswaran S, Morris M, Luo Y, Henderson D, Samayamuthu M, Tan B, Verdy G, Omenn G, Xia Z, Bellazzi R, EHR T, Aaron J, Agapito G, Albayrak A, Albi G, Alessiani M, Alloni A, Amendola D, Angoulvant F, Anthony L, Aronow B, Ashraf F, Atz A, Avillach P, Azevedo P, Balshi J, Beaulieu-Jones B, Bell D, Bellasi A, Bellazzi R, Benoit V, Beraghi M, Bernal-Sobrino J, Bernaux M, Bey R, Bhatnagar S, Blanco-Martínez A, Bonzel C, Booth J, Bosari S, Bourgeois F, Bradford R, Brat G, Bréant S, Brown N, Bruno R, Bryant W, Bucalo M, Bucholz E, Burgun A, Cai T, Cannataro M, Carmona A, Caucheteux C, Champ J, Chen J, Chen K, Chiovato L, Chiudinelli L, Cho K, Cimino J, Colicchio T, Cormont S, Cossin S, Craig J, Cruz-Bermúdez J, Cruz-Rojo J, Dagliati A, Daniar M, Daniel C, Das P, Devkota B, Dionne A, Duan R, Dubiel J, DuVall S, Esteve L, Estiri H, Fan S, Follett R, Ganslandt T, Barrio N, Garmire L, Gehlenborg N, Getzen E, Geva A, Gradinger T, Gramfort A, Griffier R, Griffon N, Grisel O, Gutiérrez-Sacristán A, Han L, Hanauer D, Haverkamp C, Hazard D, He B, Henderson D, Hilka M, Ho Y, Holmes J, Hong C, Huling K, Hutch M, Issitt R, Jannot A, Jouhet V, Kavuluru R, Keller M, Kennedy C, Key D, Kirchoff K, Klann J, Kohane I, Krantz I, Kraska D, Krishnamurthy A, L'Yi S, Le T, Leblanc J, Lemaitre G, Lenert L, Leprovost D, Liu M, Loh N, Long Q, Lozano-Zahonero S, Luo Y, Lynch K, Mahmood S, Maidlow S, Makoudjou A, Malovini A, Mandl K, Mao C, Maram A, Martel P, Martins M, Marwaha J, Masino A, Mazzitelli M, Mensch A, Milano M, Minicucci M, Moal B, Ahooyi T, Moore J, Moraleda C, Morris J, Morris M, Moshal K, Mousavi S, Mowery D, Murad D, Murphy S, Naughton T, Neto C, Neuraz A, Newburger J, Ngiam K, Njoroge W, Norman J, Obeid J, Okoshi M, Olson K, Omenn G, Orlova N, Ostasiewski B, Palmer N, Paris N, Patel L, Pedrera-Jiménez M, Pfaff E, Pfaff A, Pillion D, Pizzimenti S, Prokosch H, Prudente R, Prunotto A, Quirós-González V, Ramoni R, Raskin M, Rieg S, Roig-Domínguez G, Rojo P, Rubio-Mayo P, Sacchi P, Sáez C, Salamanca E, Samayamuthu M, Sanchez-Pinto L, Sandrin A, Santhanam N, Santos J, Vidorreta F, Savino M, Schriver E, Schubert P, Schuettler J, Scudeller L, Sebire N, Serrano-Balazote P, Serre P, Serret-Larmande A, Shah M, Abad Z, Silvio D, Sliz P, Son J, Sonday C, South A, Spiridou A, Strasser Z, Tan A, Tan B, Tan B, Tanni S, Taylor D, Terriza-Torres A, Tibollo V, Tippmann P, Toh E, Torti C, Trecarichi E, Tseng Y, Vallejos A, Varoquaux G, Vella M, Verdy G, Vie J, Visweswaran S, Vitacca M, Wagholikar K, Waitman L, Wang X, Wassermann D, Weber G, Wolkewitz M, Wong S, Xia Z, Xiong X, Ye Y, Yehya N, Yuan W, Zambelli A, Zhang H, Zo¨ller D, Zuccaro V, Zucco C, Murphy S, Holmes J, Estiri H. Characterization of long COVID temporal sub-phenotypes by distributed representation learning from electronic health record data: a cohort study. EClinicalMedicine 2023, 64: 102210. PMID: 37745021, PMCID: PMC10511779, DOI: 10.1016/j.eclinm.2023.102210.Peer-Reviewed Original ResearchElectronic health record dataHealth record dataAdvancing Translational SciencesCohort studyNational InstituteMulti-center observational cohort studyHospitalized COVID-19 patientsObservational cohort studyPost-acute sequelaeRecord dataCOVID-19 patientsHealthcare systemLongitudinal electronic health record dataMedical Research CouncilTranslational scienceNational Medical Research CouncilPASC symptomsJoint painTotal cohortClinical characterizationHigh prevalenceMultiple symptomsNeurological disordersAverage prevalenceInfectious diseases
2022
Long-term kidney function recovery and mortality after COVID-19-associated acute kidney injury: An international multi-centre observational cohort study
Tan B, Tan B, Tan A, Schriver E, Gutiérrez-Sacristán A, Das P, Yuan W, Hutch M, Barrio N, Jimenez M, Abu-el-rub N, Morris M, Moal B, Verdy G, Cho K, Ho Y, Patel L, Dagliati A, Neuraz A, Klann J, South A, Visweswaran S, Hanauer D, Maidlow S, Liu M, Mowery D, Batugo A, Makoudjou A, Tippmann P, Zöller D, Brat G, Luo Y, Avillach P, Bellazzi R, Chiovato L, Malovini A, Tibollo V, Samayamuthu M, Balazote P, Xia Z, Loh N, Chiudinelli L, Bonzel C, Hong C, Zhang H, Weber G, Kohane I, Cai T, Omenn G, Holmes J, Ngiam K, EHR T, Aaron J, Agapito G, Albayrak A, Albi G, Alessiani M, Alloni A, Amendola D, Angoulvant F, Anthony L, Aronow B, Ashraf F, Atz A, Avillach P, Panickan V, Azevedo P, Balshi J, Batugo A, Beaulieu-Jones B, Beaulieu-Jones B, Bell D, Bellasi A, Bellazzi R, Benoit V, Beraghi M, Bernal-Sobrino J, Bernaux M, Bey R, Bhatnagar S, Blanco-Martínez A, Boeker M, Bonzel C, Booth J, Bosari S, Bourgeois F, Bradford R, Brat G, Bréant S, Brown N, Bruno R, Bryant W, Bucalo M, Bucholz E, Burgun A, Cai T, Cannataro M, Carmona A, Cattelan A, Caucheteux C, Champ J, Chen J, Chen K, Chiovato L, Chiudinelli L, Cho K, Cimino J, Colicchio T, Cormont S, Cossin S, Craig J, Cruz-Bermúdez J, Cruz-Rojo J, Dagliati A, Daniar M, Daniel C, Das P, Devkota B, Dionne A, Duan R, Dubiel J, DuVall S, Esteve L, Estiri H, Fan S, Follett R, Ganslandt T, García-Barrio N, Garmire L, Gehlenborg N, Getzen E, Geva A, González T, Gradinger T, Gramfort A, Griffier R, Griffon N, Grisel O, Gutiérrez-Sacristán A, Guzzi P, Han L, Hanauer D, Haverkamp C, Hazard D, He B, Henderson D, Hilka M, Ho Y, Holmes J, Honerlaw J, Hong C, Huling K, Hutch M, Issitt R, Jannot A, Jouhet V, Kavuluru R, Keller M, Kennedy C, Kernan K, Key D, Kirchoff K, Klann J, Kohane I, Krantz I, Kraska D, Krishnamurthy A, L'Yi S, Le T, Leblanc J, Lemaitre G, Lenert L, Leprovost D, Liu M, Loh N, Long Q, Lozano-Zahonero S, Luo Y, Lynch K, Mahmood S, Maidlow S, Makoudjou A, Makwana S, Malovini A, Mandl K, Mao C, Maram A, Maripuri M, Martel P, Martins M, Marwaha J, Masino A, Mazzitelli M, Mazzotti D, Mensch A, Milano M, Minicucci M, Moal B, Ahooyi T, Moore J, Moraleda C, Morris J, Morris M, Moshal K, Mousavi S, Mowery D, Murad D, Murphy S, Naughton T, Neto C, Neuraz A, Newburger J, Ngiam K, Njoroge W, Norman J, Obeid J, Okoshi M, Olson K, Omenn G, Orlova N, Ostasiewski B, Palmer N, Paris N, Patel L, Pedrera-Jiménez M, Pfaff A, Pfaff E, Pillion D, Pizzimenti S, Priya T, Prokosch H, Prudente R, Prunotto A, Quirós-González V, Ramoni R, Raskin M, Rieg S, Roig-Domínguez G, Rojo P, Rubio-Mayo P, Sacchi P, Sáez C, Salamanca E, Samayamuthu M, Sanchez-Pinto L, Sandrin A, Santhanam N, Santos J, Vidorreta F, Savino M, Schriver E, Schubert P, Schuettler J, Scudeller L, Sebire N, Serrano-Balazote P, Serre P, Serret-Larmande A, Shah M, Abad Z, Silvio D, Sliz P, Son J, Sonday C, South A, Sperotto F, Spiridou A, Strasser Z, Tan A, Tan B, Tan B, Tanni S, Taylor D, Terriza-Torres A, Tibollo V, Tippmann P, Toh E, Torti C, Trecarichi E, Vallejos A, Varoquaux G, Vella M, Verdy G, Vie J, Visweswaran S, Vitacca M, Wagholikar K, Waitman L, Wang X, Wassermann D, Weber G, Wolkewitz M, Wong S, Xia Z, Xiong X, Ye Y, Yehya N, Yuan W, Zachariasse J, Zahner J, Zambelli A, Zhang H, Zöller D, Zuccaro V, Zucco C. Long-term kidney function recovery and mortality after COVID-19-associated acute kidney injury: An international multi-centre observational cohort study. EClinicalMedicine 2022, 55: 101724. PMID: 36381999, PMCID: PMC9640184, DOI: 10.1016/j.eclinm.2022.101724.Peer-Reviewed Original ResearchCOVID-19-associated acute kidney injuryAcute kidney injuryKidney function recoveryMulti-center observational cohort studySevere acute kidney injuryObservational cohort studyFunction recoveryKidney injuryCohort studyAdvanced ageSARS-CoV-2 infectionWorse mortality outcomesChronic kidney diseaseSevere COVID-19Subset of patientsIschemic heart diseaseKidney function impairmentSerum creatinine valuesCOVID-19 patientsCOVID-19AKI severityRemdesivir useCommon complicationClinical factorsFunction impairment