2013
Transcriptome deep-sequencing and clustering of expressed isoforms from Favia corals
Pooyaei Mehr SF, DeSalle R, Kao HT, Narechania A, Han Z, Tchernov D, Pieribone V, Gruber DF. Transcriptome deep-sequencing and clustering of expressed isoforms from Favia corals. BMC Genomics 2013, 14: 546. PMID: 23937070, PMCID: PMC3751062, DOI: 10.1186/1471-2164-14-546.Peer-Reviewed Original Research
2002
A protein kinase A–dependent molecular switch in synapsins regulates neurite outgrowth
Kao HT, Song HJ, Porton B, Ming GL, Hoh J, Abraham M, Czernik AJ, Pieribone VA, Poo MM, Greengard P. A protein kinase A–dependent molecular switch in synapsins regulates neurite outgrowth. Nature Neuroscience 2002, 5: 431-437. PMID: 11976703, DOI: 10.1038/nn840.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodiesBucladesineCells, CulturedConserved SequenceCyclic AMP-Dependent Protein KinasesEmbryo, NonmammalianEnzyme ActivatorsEnzyme InhibitorsGenes, ReporterMicroinjectionsMolecular Sequence DataMutagenesis, Site-DirectedNeuritesNeuronsPhosphorylationRNA, MessengerSequence Homology, Amino AcidSynapsinsXenopus laevisConceptsProtein kinase ANeurite outgrowthCAMP/protein kinase APhospho-specific antibodiesSingle amino acid residueX. laevis embryosAmino acid residuesDependent molecular switchPhosphorylation of synapsinCyclic AMPEmbryonic neuronal culturesNeuronal cell lineProtein kinaseConstitutive phosphorylationKinase AMolecular approachesMolecular switchAcid residuesLaevis embryosPKA inhibitorPotential molecular approachPhosphorylationGrowth-promoting actionCell linesSynapsin
2000
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
Bibb J, Yan Z, Svenningsson P, Snyder G, Pieribone V, Horiuchi A, Nairn A, Messer A, Greengard P. Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 6809-6814. PMID: 10829080, PMCID: PMC18747, DOI: 10.1073/pnas.120166397.Peer-Reviewed Original ResearchConceptsMedium spiny neuronsDisease miceSpiny neuronsStriatal medium spiny neuronsHuntington's diseaseSevere deficiencyHuntington's disease miceHD model miceModel miceDopaminergic neurotransmissionHD miceSelective neurodegenerationHD pathologyMiceDARPP-32DopamineHuman huntingtinBehavioral phenotypesDiseaseNeuronsIon channelsTotal levelsDisease-causing formHuntingtinDeficiency
1998
Galanin–5-hydroxytryptamine interactions: electrophysiological, immunohistochemical and in situ hybridization studies on rat dorsal raphe neurons with a note on galanin R1 and R2 receptors
Xu Z, Zhang X, Pieribone VA, Grillner S, Hökfelt T. Galanin–5-hydroxytryptamine interactions: electrophysiological, immunohistochemical and in situ hybridization studies on rat dorsal raphe neurons with a note on galanin R1 and R2 receptors. Neuroscience 1998, 87: 79-94. PMID: 9722143, DOI: 10.1016/s0306-4522(98)00151-1.Peer-Reviewed Original ResearchConceptsDorsal raphe neuronsRaphe neuronsRat dorsal raphe neuronsCell bodiesOutward currentsInhibitory effectGalanin-like immunoreactivityDorsal raphe nucleusDose-dependent hyperpolarizationExtracellular potassium concentrationGalaninergic mechanismsSitu hybridization studiesGalanin receptorsRaphe nucleusSynaptic contactsNerve endingsPostsynaptic receptorsSoma levelGalaninImmunohistochemical analysisR2 receptorsGalanin R1NeuronsMood regulationPhysiological concentrations
1996
The distribution and significance of CNS adrenoceptors examined with in situ hybridization
Nicholas A, Hökfely T, Pieribone V. The distribution and significance of CNS adrenoceptors examined with in situ hybridization. Trends In Pharmacological Sciences 1996, 17: 245-255. PMID: 8756183, DOI: 10.1016/0165-6147(96)10022-5.Peer-Reviewed Original Research
1995
A Complementary Method to Radioligand‐Mediated Autoradiography for Localizing Adrenergic, Alpha‐2 Receptor‐Producing Cellsfn2
NICHOLAS A, PIERIBONE V, DAGERLIND Å, MEISTER B, ELDE R, HÖKFELT T. A Complementary Method to Radioligand‐Mediated Autoradiography for Localizing Adrenergic, Alpha‐2 Receptor‐Producing Cellsfn2. Annals Of The New York Academy Of Sciences 1995, 763: 222-242. PMID: 7677334, DOI: 10.1111/j.1749-6632.1995.tb32409.x.Peer-Reviewed Original Research
1994
Distribution of alpha 1 adrenoceptors in rat brain revealed by in situ hybridization experiments utilizing subtype-specific probes
Pieribone V, Nicholas A, Dagerlind A, Hokfelt T. Distribution of alpha 1 adrenoceptors in rat brain revealed by in situ hybridization experiments utilizing subtype-specific probes. Journal Of Neuroscience 1994, 14: 4252-4268. PMID: 8027777, PMCID: PMC6577046, DOI: 10.1523/jneurosci.14-07-04252.1994.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainIn Situ HybridizationMaleRatsRats, Sprague-DawleyReceptors, Adrenergic, alphaRNA, MessengerTissue DistributionConceptsAlpha 1A/DSpinal motor nucleiSpinal cordCerebral cortexMotor nucleusAmygdaloid nucleusLight labellingCA1-CA4 regionsAlpha-1 adrenoceptorsAlpha 1B-adrenoceptorsIntermediolateral cell columnInternal plexiform layerLateral amygdaloid nucleusReticular thalamic nucleusDistribution of neuronsMedullary raphe nucleiMedullary reticular formationCentral amygdaloid nucleusLateral hypothalamic nucleusInferior olivary nucleusReceptor distribution patternsSubtype-specific probesAdrenoceptor mRNANoradrenergic innervationAdrenoceptor subtypesNeuropeptide role of both peptide YY and neuropeptide Y in vertebrates suggested by abundant expression of their mRNAS in a cyclostome brain
Söderberg C, Pieribone VA, Dahlstrand J, Brodin L, Larhammar D. Neuropeptide role of both peptide YY and neuropeptide Y in vertebrates suggested by abundant expression of their mRNAS in a cyclostome brain. Journal Of Neuroscience Research 1994, 37: 633-640. PMID: 8028041, DOI: 10.1002/jnr.490370510.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBrainDNA, ComplementaryGene Expression RegulationHumansIn Situ HybridizationIntestinal MucosaLampreysMolecular Sequence DataNeuropeptide YOrgan SpecificityPeptide BiosynthesisPeptide YYPeptidesPhylogenyRNA, MessengerSequence HomologySpecies SpecificityVertebrates
1993
Cellular localization of messenger RNA for beta-1 and beta-2 adrenergic receptors in rat brain: An in situ hybridization study
Nicholas AP, Pieribone VA, Hökfelt T. Cellular localization of messenger RNA for beta-1 and beta-2 adrenergic receptors in rat brain: An in situ hybridization study. Neuroscience 1993, 56: 1023-1039. PMID: 8284033, DOI: 10.1016/0306-4522(93)90148-9.Peer-Reviewed Original ResearchConceptsSpinal cordRat brainCentral nervous system circuitryBeta 1Messenger RNABeta-receptor subtypesThalamic intralaminar nucleiAnterior olfactory nucleusBeta 1 receptorsIntermediate gray matterReticular thalamic nucleusMedullary reticular formationNervous system circuitryReceptor messenger RNABeta 1 messenger RNABeta-2 adrenergic receptorsCentral nervous systemRat beta 1Selective labeling patternsDeep cerebellar nucleiUnfixed rat brainOlfactory nucleusTrapezoid nucleusCerebral cortexSitu hybridization studiesDistributions of mRNAs for alpha‐2 adrenergic receptor subtypes in rat brain: An in situ hybridization study
Nicholas A, Pieribone V, Hökfelt T. Distributions of mRNAs for alpha‐2 adrenergic receptor subtypes in rat brain: An in situ hybridization study. The Journal Of Comparative Neurology 1993, 328: 575-594. PMID: 8381444, DOI: 10.1002/cne.903280409.Peer-Reviewed Original ResearchConceptsCentral nervous systemNervous systemCerebral cortexSpinal cordReceptor subtypesRat brainAlpha-2 adrenergic receptor subtypesVentrolateral medullary reticular formationRat central nervous systemAlpha-2 receptor subtypesMRNA labelingAlpha 2 receptorsIntermediolateral cell columnThoracic spinal cordNucleus tractus solitariiReticular thalamic nucleusHypothalamic paraventricular nucleusMedullary reticular formationDorsal root gangliaIslands of CallejaAdrenergic receptor subtypesSelective labeling patternsDeep cerebellar nucleiAlpha 2 probeRat alpha-2A
1992
Differential expression of mRNAs for neuropeptide Y-related peptides in rat nervous tissues: possible evolutionary conservation
Pieribone V, Brodin L, Friberg K, Dahlstrand J, Soderberg C, Larhammar D, Hokfelt T. Differential expression of mRNAs for neuropeptide Y-related peptides in rat nervous tissues: possible evolutionary conservation. Journal Of Neuroscience 1992, 12: 3361-3371. PMID: 1527583, PMCID: PMC6575750, DOI: 10.1523/jneurosci.12-09-03361.1992.Peer-Reviewed Original ResearchConceptsNeuropeptide YPeripheral nerve gangliaRat nervous tissuePopulations of neuronsBrainstem neuronsNPY mRNASympathetic gangliaAdrenal glandCaudal medullaCNS neuronsSpinal cordRostral medullaNerve gangliaRat CNSRat brainVisceral organsMammalian CNSPYY mRNANervous tissuePYY immunoreactivityEndocrine cellsPP mRNAPYYNeuronsMidline region