2024
Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy
Greenland P, Segal M, McNeil R, Parker C, Pemberton V, Grobman W, Silver R, Simhan H, Saade G, Ganz P, Mehta P, Catov J, Merz C, Varagic J, Khan S, Parry S, Reddy U, Mercer B, Wapner R, Haas D. Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy. JAMA Cardiology 2024, 9: 791-799. PMID: 38958943, PMCID: PMC11223045, DOI: 10.1001/jamacardio.2024.1621.Peer-Reviewed Original ResearchArea under the receiver operating characteristic curveCase-control studyHypertensive disordersEarly pregnancyClinical dataSmall-for-gestational-age infantsPrediction of hypertensive disordersSmall-for-gestational-ageHypertensive disorders of pregnancyPrediction of HDPDisorders of pregnancyNested case-control studyPlasma samplesMulticenter observational studyStored plasma samplesReceiver operating characteristic curveBody mass indexGestational hypertensionNon-Hispanic blacksPreterm birthFetal sexFirst-trimesterNon-Hispanic whitesPregnancy outcomesMaternal race
2023
Macroscopic lesions of maternal and fetal vascular malperfusion in stillborn placentas: Diagnosis in the absence of microscopic histopathological examination
Cersonsky T, Silver R, Saade G, Dudley D, Reddy U, Pinar H. Macroscopic lesions of maternal and fetal vascular malperfusion in stillborn placentas: Diagnosis in the absence of microscopic histopathological examination. Placenta 2023, 140: 60-65. PMID: 37536149, PMCID: PMC10530266, DOI: 10.1016/j.placenta.2023.07.296.Peer-Reviewed Original ResearchConceptsFetal vascular malperfusionMaternal vascular malperfusionVascular malperfusionLive birthsFVM lesionsGestational ageMacroscopic findingsAmsterdam Placental Workshop Group Consensus StatementStillbirth Collaborative Research NetworkMicroscopic histopathological examinationMicroscopic pathologic evaluationHistory of hypertensionOdds of stillbirthGroup Consensus StatementMultivariate logistic regressionMVM lesionsPathologic evaluationHistopathological examinationMaternal raceOdds ratioConsensus statementHigher oddsUmbilical cordStillbirthMaternal factors