2024
Patient and community centered approaches to sepsis among birthing people
Richardson B, Cepin A, Grilo S, Moss R, Moller M, Brown S, Goffman D, Friedman A, Reddy U, Hall K. Patient and community centered approaches to sepsis among birthing people. Seminars In Perinatology 2024, 48: 151974. PMID: 39341761, PMCID: PMC11568907, DOI: 10.1016/j.semperi.2024.151974.Peer-Reviewed Original ResearchMaternal health equityHealth equityAcademic-community research partnershipsSevere maternal morbidityCo-designed interventionsBirthing peopleMaternal deathsUnderserved communitiesMaternal morbidityMoms studyResearch partnershipsSepsis-related morbidityCommunity centered approachRisk periodResearch principalsResearch processCentered approachCommunityMorbidityPeoplePostpartumInterventionEquityPartnershipBirthMaternal implications of fetal anomalies: a population-based cross-sectional study
Atwani R, Aziz M, Saade G, Reddy U, Kawakita T. Maternal implications of fetal anomalies: a population-based cross-sectional study. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101440. PMID: 39089580, DOI: 10.1016/j.ajogmf.2024.101440.Peer-Reviewed Original ResearchCongenital diaphragmatic herniaCongenital heart diseasePresence of fetal anomaliesAdjusted relative risksFetal anomaliesCleft lipMaternal morbidityDiaphragmatic herniaAdjusted risk differencesChromosomal disordersMultiple anomaliesLimb anomaliesHeart diseaseMaternal intensive care unit admissionRisk of severe maternal morbidityAssociated with maternal morbidityCyanotic congenital heart diseaseMultiple fetal anomaliesRisk of SMMAdverse maternal health outcomesIntensive care unit admissionAdverse maternal outcomesPopulation-based cross-sectional studySevere maternal morbidityIncreased absolute riskInfection and Sepsis Trends during United States' Delivery Hospitalizations from 2000 to 2020
Liu L, Friedman A, Goffman D, Nathan L, Sheen J, Reddy U, D'Alton M, Wen T. Infection and Sepsis Trends during United States' Delivery Hospitalizations from 2000 to 2020. American Journal Of Perinatology 2024, 41: 1767-1778. PMID: 38408480, DOI: 10.1055/s-0044-1780538.Peer-Reviewed Original ResearchChronic health conditionsChronic condition diagnosesSevere maternal morbidityDelivery hospitalizationsHealth conditionsAdverse obstetric outcomesMaternal morbidityWound infectionAssociated with chronic health conditionsInfection diagnosisStudy periodObstetric outcomesEvaluate trendsCross-sectional analysisLogistic regression modelsMeasures of associationNational Inpatient SampleChronic conditionsHospital characteristicsAcute renal failureHospitalization of patientsPresence of sepsisOdds ratioCondition diagnosisInpatient SamplePostpartum readmission risk: a comparison between stillbirths and live births
Sweeney L, Reddy U, Campbell K, Xu X. Postpartum readmission risk: a comparison between stillbirths and live births. American Journal Of Obstetrics And Gynecology 2024, 231: 463.e1-463.e14. PMID: 38367754, DOI: 10.1016/j.ajog.2024.02.017.Peer-Reviewed Original ResearchRisk of readmissionMental health/substance use disordersPostpartum readmissionHigher risk of readmissionLive birthsRisk of postpartum readmissionSecondary outcomesDelivery characteristicsNationally representative estimatesComplex sampling designRisk factorsIncreased maternal morbidityHigher household incomeTime of readmissionWeeks of dischargeHypertensive disorders of pregnancyUse disorderHigh riskVenous thromboembolismChildbirth hospitalizationPrimary cesareanSingleton stillbirthsDisorders of pregnancyMultivariate regression modelMaternal morbidity
2023
Association of maternal body mass index with success and outcomes of attempted operative vaginal delivery
Grasch J, Venkatesh K, Grobman W, Silver R, Saade G, Mercer B, Yee L, Scifres C, Parry S, Simhan H, Reddy U, Frey H. Association of maternal body mass index with success and outcomes of attempted operative vaginal delivery. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101081. PMID: 37422004, DOI: 10.1016/j.ajogmf.2023.101081.Peer-Reviewed Original ResearchConceptsMaternal body mass indexBody mass indexOperative vaginal deliveryVaginal delivery attemptComposite maternal morbidityComposite neonatal morbidityVaginal deliveryMass indexNeonatal morbidityCesarean deliveryMaternal morbidityAdverse outcomesSecond-stage cesarean deliveryBody mass index groupsBody mass index categoriesNulliparous Pregnancy Outcomes StudyNonanomalous singleton pregnanciesNeonatal adverse outcomesMultivariable logistic regressionPregnancy Outcomes StudyNulliparous individualsDose-dependent mannerSecondary outcomesSingleton pregnanciesPrimary outcomeMaternal Morbidity Risk Factors in Nulliparas
Merriam A, Metz T, Allshouse A, Silver R, Haas D, Grobman W, Simhan H, Wapner R, Wing D, Mercer B, Parry S, Reddy U, Investigators +. Maternal Morbidity Risk Factors in Nulliparas. American Journal Of Perinatology 2023, 41: e1878-e1884. PMID: 37150178, DOI: 10.1055/a-2088-2586.Peer-Reviewed Original ResearchVenous thromboembolic eventsSelf-identified black raceComposite maternal morbidityPrimary maternal outcomeSevere maternal morbidityMaternal morbidityChronic kidney diseaseBlack raceRisk factorsChronic hypertensionHypertensive disordersMaternal outcomesPregestational diabetesKidney diseaseMedical conditionsMulticenter prospective observational cohortPrepregnancy body mass indexPreexisting medical comorbiditiesPrior obstetric historyProspective observational cohortMorbidity risk factorsBody mass indexMultiple risk factorsDays of deliveryLog-binomial regressionOutcomes of induction vs prelabor cesarean delivery at <33 weeks for hypertensive disorders of pregnancy
Bushman E, Grobman W, Bailit J, Reddy U, Wapner R, Varner M, Thorp J, Caritis S, Prasad M, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J, Network E. Outcomes of induction vs prelabor cesarean delivery at <33 weeks for hypertensive disorders of pregnancy. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101032. PMID: 37244639, PMCID: PMC10521213, DOI: 10.1016/j.ajogmf.2023.101032.Peer-Reviewed Original ResearchConceptsPrelabor cesarean deliveryHypertensive disordersInduction of laborCesarean deliveryLabor inductionNeonatal morbidityInduction groupMedian durationVaginal deliveryWeeks' gestationSecondary analysisAdverse composite outcomeComposite maternal morbidityOutcome of inductionPreterm hypertensive disordersHalf of patientsCesarean delivery groupLength of inductionOptimal delivery approachMaternal morbidityComposite outcomeFetal malpresentationMultiple gestationsPreterm birthSecondary outcomesHypertension in Pregnancy and Adverse Outcomes Among Low-risk Nulliparous Women Expectantly Managed at or After 39 weeks: A Secondary Analysis of a Randomized Controlled Trial
Bartal M, Premkumar A, Rice M, Reddy U, Tita A, Silver R, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Constantine M, Chien E, Casey B, Srinivas S, Swamy G, Simhan H. Hypertension in Pregnancy and Adverse Outcomes Among Low-risk Nulliparous Women Expectantly Managed at or After 39 weeks: A Secondary Analysis of a Randomized Controlled Trial. Obstetric Anesthesia Digest 2023, 43: 82-82. DOI: 10.1097/01.aoa.0000927856.60760.92.Peer-Reviewed Original ResearchLow-risk patientsLow-risk nulliparous womenHypertensive disordersMaternal morbidityMaternal outcomesNulliparous womenControlled TrialsWeeks' gestationAdverse outcomesLower riskSecondary analysisPregnancyPatientsHDPOutcomesRecent studiesHypertensionMorbidityGestationMortalityPrevalenceTrialsWeeksWomen
2021
Outcomes in Twins Compared With Singletons Subsequent to Preterm Prelabor Rupture of Membranes
Bartal M, Ugwu LG, Grobman WA, Bailit JL, Reddy UM, Wapner RJ, Varner MW, Thorp JM, Caritis SN, Prasad M, Tita ATN, Saade GR, Rouse DJ. Outcomes in Twins Compared With Singletons Subsequent to Preterm Prelabor Rupture of Membranes. Obstetrics And Gynecology 2021, 138: 725-731. PMID: 34619719, PMCID: PMC8542618, DOI: 10.1097/aog.0000000000004561.Peer-Reviewed Original ResearchMeSH KeywordsAdultChorioamnionitisCohort StudiesEndometritisEnterocolitis, NecrotizingFemaleFetal Membranes, Premature RuptureGestational AgeHumansInfant, NewbornInfant, PrematureOutcome Assessment, Health CarePerinatal MortalityPregnancyPregnancy OutcomePregnancy, TwinPremature BirthSepsisVenous ThromboembolismWound InfectionYoung AdultConceptsComposite maternal morbidityPreterm prelabor ruptureWeeks of gestationNeonatal morbidityPreterm PROMSingleton gestationsMaternal morbidityPrelabor ruptureTwin gestationsOdds ratioComposite major neonatal morbidityComposite neonatal morbidityMajor neonatal morbidityMedian gestational ageMedian latency periodMajor fetal anomaliesAdjusted odds ratioCoprimary outcomesObstetric cohortNeonatal outcomesTwin neonatesGestational agePotential confoundersFetal anomaliesMorbidity
2020
Severe Maternal Morbidity During Delivery Hospitalization in a Large International Administrative Database, 2008-2013: A Retrospective Cohort
Lipkind H, Zuckerwise L, Turner E, Collins J, Campbell K, Reddy U, Illuzi J, Merriam A. Severe Maternal Morbidity During Delivery Hospitalization in a Large International Administrative Database, 2008-2013: A Retrospective Cohort. Obstetric Anesthesia Digest 2020, 40: 90-90. DOI: 10.1097/01.aoa.0000661440.79132.dd.Peer-Reviewed Original Research
2019
Severe maternal morbidity during delivery hospitalisation in a large international administrative database, 2008–2013: a retrospective cohort
Lipkind H, Zuckerwise L, Turner E, Collins J, Campbell K, Reddy U, Illuzi J, Merriam A. Severe maternal morbidity during delivery hospitalisation in a large international administrative database, 2008–2013: a retrospective cohort. BJOG An International Journal Of Obstetrics & Gynaecology 2019, 126: 1223-1230. PMID: 31100201, DOI: 10.1111/1471-0528.15818.Peer-Reviewed Original ResearchMeSH KeywordsAdultAustraliaCenters for Disease Control and Prevention, U.S.ComorbidityDatabases, FactualEnglandFemaleHospitalizationHumansMaternal AgeMaternal DeathMiddle AgedObstetric Labor ComplicationsPregnancyPregnancy ComplicationsPregnancy OutcomeRetrospective StudiesRisk FactorsUnited StatesYoung AdultConceptsSevere maternal morbidityMaternal morbidityDelivery hospitalisationRetrospective cohortRisk factorsSevere maternal morbidity ratesMaternal morbidity ratesAcute renal failureLife-threatening diagnosisAdvanced maternal ageLife-saving procedureLarge university hospitalChi-square testMorbidity variesPregnancy complicationsClinical characteristicsIntravascular coagulationRenal failureSevere morbidityMultivariable analysisMorbidity rateAdverse outcomesClinical differencesMaternal ageUniversity HospitalPredictors of Sleep-disordered Breathing in Pregnancy
Louis J, Koch M, Reddy U, Silver R, Parker C, Facco F, Redline S, Nhan-Chang C, Chung J, Pien G, Basner R, Grobman W, Wing D, Simhan H, Haas D, Mercer B, Parry S, Mobley D, Carper B, Saade G, Schubert F, Zee P. Predictors of Sleep-disordered Breathing in Pregnancy. Obstetric Anesthesia Digest 2019, 39: 36-37. DOI: 10.1097/01.aoa.0000552909.82459.b1.Peer-Reviewed Original ResearchSleep-disordered breathingDiagnosis of SDBSevere maternal morbidityRisk of complicationsMaternal morbidityPreterm deliverySDB symptomsVenous thromboembolismMaternal deathsOvernight polysomnographyPregnant womenAdverse outcomesLarge cohortFeasible prediction modelPregnancyBreathingWomenThromboembolismPreeclampsiaMorbidityComplicationsPolysomnographyCohortSymptomsDiagnosis