2022
Copy number variants and fetal growth in stillbirths
Dalton S, Workalemahu T, Allshouse A, Page J, Reddy U, Saade G, Pinar H, Goldenberg R, Dudley D, Silver R. Copy number variants and fetal growth in stillbirths. American Journal Of Obstetrics And Gynecology 2022, 228: 579.e1-579.e11. PMID: 36356697, PMCID: PMC10149588, DOI: 10.1016/j.ajog.2022.11.1274.Peer-Reviewed Original ResearchConceptsAbnormal copy number variantsFetal growth abnormalitiesGestational ageOdds ratioStillbirth Collaborative Research NetworkGenetic abnormalitiesChromosomal microarrayGestational age outcomesGestational age infantsGrowth abnormalitiesClinical risk factorsCohort study designAdjusted odds ratioCopy number variantsUnknown clinical significancePathogenic copy number variantsPlacental insufficiencyAge infantsNumber variantsFetal growthMaternal ageRisk factorsClinical significanceHigh incidenceStillbirth
2012
Karyotype versus Microarray Testing for Genetic Abnormalities after Stillbirth
Reddy UM, Page GP, Saade GR, Silver RM, Thorsten VR, Parker CB, Pinar H, Willinger M, Stoll BJ, Heim-Hall J, Varner MW, Goldenberg RL, Bukowski R, Wapner RJ, Drews-Botsch CD, O'Brien BM, Dudley DJ, Levy B. Karyotype versus Microarray Testing for Genetic Abnormalities after Stillbirth. New England Journal Of Medicine 2012, 367: 2185-2193. PMID: 23215556, PMCID: PMC4295117, DOI: 10.1056/nejmoa1201569.Peer-Reviewed Original ResearchConceptsGenetic abnormalitiesAntepartum stillbirthCongenital anomaliesMicroarray analysisStillbirth Collaborative Research NetworkCopy number variantsAnalysis of stillbirthPopulation-based studyKaryotype analysisResults of karyotypeGeographic catchment areaSingle nucleotide polymorphism arrayClinical significancePostmortem examinationNonviable tissueStillbirthTrue prevalenceFetal tissuesUnaffected personsAbnormalitiesKaryotype resultsMicroarray testingCollaborative research networksGenetic diagnosisPolymorphism array
2007
Work-up of stillbirth: a review of the evidence
Silver RM, Varner MW, Reddy U, Goldenberg R, Pinar H, Conway D, Bukowski R, Carpenter M, Hogue C, Willinger M, Dudley D, Saade G, Stoll B. Work-up of stillbirth: a review of the evidence. American Journal Of Obstetrics And Gynecology 2007, 196: 433-444. PMID: 17466694, PMCID: PMC2699761, DOI: 10.1016/j.ajog.2006.11.041.Peer-Reviewed Original ResearchConceptsCauses of stillbirthStillbirth Collaborative Research NetworkFetal-maternal hemorrhageWeeks of gestationUtero fetal deathProportion of stillbirthsFetal deathIntrapartum carePrecise etiologyMedical conditionsChild healthStillbirthAcademic centersDiagnostic testsGenetic abnormalitiesNational InstituteCollaborative research networksResearch NetworkUnited StatesDiagnostic explanationCauseSystematic evaluationHemorrhageReviewGestation