2023
Transmission modeling to infer tuberculosis incidence prevalence and mortality in settings with generalized HIV epidemics
Dodd P, Shaweno D, Ku C, Glaziou P, Pretorius C, Hayes R, MacPherson P, Cohen T, Ayles H. Transmission modeling to infer tuberculosis incidence prevalence and mortality in settings with generalized HIV epidemics. Nature Communications 2023, 14: 1639. PMID: 36964130, PMCID: PMC10037365, DOI: 10.1038/s41467-023-37314-1.Peer-Reviewed Original ResearchConceptsHigh HIV prevalence settingsEstimation of burdenHIV prevalence settingsGeneralized HIV epidemicsTB transmission modelAntiretroviral therapyTB infectionTB incidenceHIV prevalenceTB prevalencePrevalence settingsTB epidemicHIV epidemicHigh burdenBurden estimatesNotification dataAnnual riskSingle pathogenIntervention impactTherapy effectsTuberculosisPrevalenceEpidemicBurdenAfrican countries
2019
Cost‐effectiveness of expanding the capacity of opioid agonist treatment in Ukraine: dynamic modeling analysis
Morozova O, Crawford FW, Cohen T, Paltiel AD, Altice FL. Cost‐effectiveness of expanding the capacity of opioid agonist treatment in Ukraine: dynamic modeling analysis. Addiction 2019, 115: 437-450. PMID: 31478285, PMCID: PMC7015766, DOI: 10.1111/add.14797.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentOpioid use disorderOAT coverageAgonist treatmentGross domestic productOpioid use initiationOpioid addiction epidemicOAT accessHIV epidemicUse disordersAddiction epidemicCapita gross domestic productPay thresholdsTreatment demandUse initiationAddiction treatmentIncremental costBaseline capacityTreatmentPotential peer effectsDomestic productTreatment spilloversEpidemicPeer effectsCoverage levels
2018
ADAPTIVE DECISION‐MAKING DURING EPIDEMICS
Yaesoubi R, Cohen T. ADAPTIVE DECISION‐MAKING DURING EPIDEMICS. 2018, 59-79. DOI: 10.1002/9781118960158.ch3.ChaptersIntegrated analytical frameworkPolicy makersEconomic costsTransmission-reducing interventionsAnalytical frameworkSubstantial healthPopulation healthNovel viral strainsDecisionsResource constraintsAvailability of resourcesEmploymentAvailable interventionsMakersInfluenza epidemicsDifficult decisionsViral strainsInfectious diseasesCostEpidemicInterventionDecision pointsEpidemic dataHealth
2016
Benefits of continuous isoniazid preventive therapy may outweigh resistance risks in a declining tuberculosis/HIV coepidemic
Kunkel A, Crawford FW, Shepherd J, Cohen T. Benefits of continuous isoniazid preventive therapy may outweigh resistance risks in a declining tuberculosis/HIV coepidemic. AIDS 2016, 30: 2715-2723. PMID: 27782966, PMCID: PMC5089846, DOI: 10.1097/qad.0000000000001235.Peer-Reviewed Original ResearchConceptsContinuous isoniazid preventive therapyIsoniazid preventive therapyIsoniazid-resistant tuberculosisTB epidemicPreventive therapyEffective TB treatmentLatent TB infectionTB drug resistanceTransmission dynamic modelTB infectionMortality benefitTB treatmentHIV controlHIV incidenceTB incidenceTB transmissionCase findingDrug resistanceIncidenceTuberculosisInitial benefitPLHIVHIVTherapyEpidemicIdentifying cost‐effective dynamic policies to control epidemics
Yaesoubi R, Cohen T. Identifying cost‐effective dynamic policies to control epidemics. Statistics In Medicine 2016, 35: 5189-5209. PMID: 27449759, PMCID: PMC5096998, DOI: 10.1002/sim.7047.Peer-Reviewed Original ResearchConceptsNet health benefitHighest net health benefitHealth benefitsTransmission-reducing interventionsDynamic policiesNovel viral pathogensCurrent interventionsHealth policyMathematical decision modelViral pathogensMonetary outcomesPolicy makersInterventionPolicyDecision modelStatic policyEpidemicEpidemic dataVaccinationVaccinePerformance measures
2011
Dynamic Health Policies for Controlling the Spread of Emerging Infections: Influenza as an Example
Yaesoubi R, Cohen T. Dynamic Health Policies for Controlling the Spread of Emerging Infections: Influenza as an Example. PLOS ONE 2011, 6: e24043. PMID: 21915279, PMCID: PMC3167826, DOI: 10.1371/journal.pone.0024043.Peer-Reviewed Original ResearchConceptsHealth policyTransmission-reducing interventionsOverall population healthType of interventionAntiviral drugsNovel infectious pathogensOverall healthEmerging InfectionsInfectious pathogensMask useCurrent interventionsCourse of epidemicsPopulation healthInterventionEpidemicPublic healthVaccineInfluenzaHealthDisease spreadSocial distancingCurrent informationInfection
2009
Use of Cumulative Incidence of Novel Influenza A/H1N1 in Foreign Travelers to Estimate Lower Bounds on Cumulative Incidence in Mexico
Lipsitch M, Lajous M, O'Hagan JJ, Cohen T, Miller JC, Goldstein E, Danon L, Wallinga J, Riley S, Dowell SF, Reed C, McCarron M. Use of Cumulative Incidence of Novel Influenza A/H1N1 in Foreign Travelers to Estimate Lower Bounds on Cumulative Incidence in Mexico. PLOS ONE 2009, 4: e6895. PMID: 19742302, PMCID: PMC2731883, DOI: 10.1371/journal.pone.0006895.Peer-Reviewed Original ResearchConceptsInfluenza A/H1N1Influenza A/Cumulative incidenceNovel influenza A/Severity of illnessSeverity of diseaseSevere diseaseTotal numberSevere symptomsNumber of casesDisease severityCurrent epidemicInfectious diseasesCanadian travellersIncidenceDiseaseAffected individualsSeverityH1N1Mexican residentsObserved groupEpidemicNovel pathogensDisease spreadResidents
2008
Mathematical Modeling of Tuberculosis Transmission Dynamics
Cohen T, Colijn C, Murray M. Mathematical Modeling of Tuberculosis Transmission Dynamics. 2008, 227-243. DOI: 10.1002/9783527611614.ch44.Peer-Reviewed Original ResearchMathematical modelBehavior of epidemicsSimple mathematical modelEpidemic modelMathematical modelingTuberculosis transmission dynamicsTuberculosis dynamicsDynamic modelNatural courseTB epidemicDynamicsNatural historyInfectious diseasesTransmission dynamicsMycobacterium tuberculosisDiseaseModelQuantitative insightsKey parametersInterventionEpidemicImportant toolComplicating factorsPotential effectsModeling
2007
Emergent heterogeneity in declining tuberculosis epidemics
Colijn C, Cohen T, Murray M. Emergent heterogeneity in declining tuberculosis epidemics. Journal Of Theoretical Biology 2007, 247: 765-774. PMID: 17540410, PMCID: PMC2652758, DOI: 10.1016/j.jtbi.2007.04.015.Peer-Reviewed Original Research