2024
Emergency Department Visits Among Patients With Dementia Before and After Diagnosis
Gettel C, Song Y, Rothenberg C, Kitchen C, Gilmore-Bykovskyi A, Fried T, Brody A, Nothelle S, Wolff J, Venkatesh A. Emergency Department Visits Among Patients With Dementia Before and After Diagnosis. JAMA Network Open 2024, 7: e2439421. PMID: 39401040, PMCID: PMC11581500, DOI: 10.1001/jamanetworkopen.2024.39421.Peer-Reviewed Original Research
2023
Validation of Electronic Health Record-Based Algorithms to Identify Specialist Palliative Care Within the Department of Veterans Affairs
Feder S, Zhan Y, Abel E, Smith D, Ersek M, Fried T, Redeker N, Akgün K. Validation of Electronic Health Record-Based Algorithms to Identify Specialist Palliative Care Within the Department of Veterans Affairs. Journal Of Pain And Symptom Management 2023, 66: e475-e483. PMID: 37364737, PMCID: PMC10527602, DOI: 10.1016/j.jpainsymman.2023.06.023.Peer-Reviewed Original ResearchConceptsSpecialist palliative careInpatient encountersCurrent Procedural TerminologyPalliative careICD-9/ICDICD-9/10 codesCohort of peopleVeterans Affairs facilitiesStop codeNegative predictive valueElectronic health recordsChart reviewHeart failureAdministrative databasesSpecific clinicPredictive valueICD codesProcedural TerminologyVeterans AffairsOutpatientsHealth recordsAdministrative dataReference standardCareConsultation
2022
“Been there, done that:” A grounded theory of future caregiver preparedness in former caregivers of parents living with dementia
Mroz E, Piechota A, Ali T, Matta‐Singh T, Abboud A, Sharma S, White M, Fried T, Monin J. “Been there, done that:” A grounded theory of future caregiver preparedness in former caregivers of parents living with dementia. Journal Of The American Geriatrics Society 2022, 71: 1495-1504. PMID: 36571504, PMCID: PMC10175151, DOI: 10.1111/jgs.18209.Peer-Reviewed Original ResearchEffect of Computer-Tailored Print Feedback, Motivational Interviewing, and Motivational Enhancement Therapy on Engagement in Advance Care Planning
Fried T, Yang M, Martino S, Iannone L, Zenoni M, Blakley L, O’Leary J, Redding C, Paiva A. Effect of Computer-Tailored Print Feedback, Motivational Interviewing, and Motivational Enhancement Therapy on Engagement in Advance Care Planning. JAMA Internal Medicine 2022, 182: 1298-1305. PMID: 36342678, PMCID: PMC9641591, DOI: 10.1001/jamainternmed.2022.5074.Peer-Reviewed Original ResearchConceptsAdvance care planningMotivational enhancement therapyMotivational interviewingUsual careClinical trialsCare planningEnhancement therapySingle VA facilityPrimary care visitsPrimary care patientsList of patientsSelf-administered toolClinician-led approachQuantity of lifeACP activityHealth care agentSelf-reported completionOversampling of womenElectronic health recordsCare visitsCare patientsTelephone contactOlder veteransMAIN OUTCOMETelephone assessmentGiving up on the objective of providing goal‐concordant care: Advance care planning for improving caregiver outcomes
Fried TR. Giving up on the objective of providing goal‐concordant care: Advance care planning for improving caregiver outcomes. Journal Of The American Geriatrics Society 2022, 70: 3006-3011. PMID: 35974460, PMCID: PMC9588724, DOI: 10.1111/jgs.18000.Peer-Reviewed Original ResearchConceptsAdvance care planningGoal-concordant careCaregiver outcomesCare planningAdvance directivesPost-traumatic stress disorderEnd of lifeAdverse outcomesPatient goalsPatient Self-Determination ActElevated riskPatient's life storyAppropriate careSelf-Determination ActStress disorderCareCaregiversHealthcare agentsOutcomesPatientsFacilitation of communicationPrimary objectiveCritical determinantClinicians
2021
Effect of the STAMP (Sharing and Talking About My Preferences) Intervention on Completing Multiple Advance Care Planning Activities in Ambulatory Care : A Cluster Randomized Controlled Trial.
Fried TR, Paiva AL, Redding CA, Iannone L, O'Leary JR, Zenoni M, Risi MM, Mejnartowicz S, Rossi JS. Effect of the STAMP (Sharing and Talking About My Preferences) Intervention on Completing Multiple Advance Care Planning Activities in Ambulatory Care : A Cluster Randomized Controlled Trial. Annals Of Internal Medicine 2021, 174: 1519-1527. PMID: 34461035, PMCID: PMC8711627, DOI: 10.7326/m21-1007.Peer-Reviewed Original ResearchConceptsAdvance care planning activitiesCare planning activitiesAmbulatory care settingsAdvance care planningCare planningCare settingsNon-English speaking participantsSpecialty care practicesUsual care sitesPrespecified subgroup analysisPatient sociodemographic informationNational InstituteParticipant-level analysesQuantity of lifeHealth care agentSecondary outcomesUsual carePrimary outcomeControlled TrialsMean ageSubgroup analysisBlinded interviewersAmbulatory careCare sitesPrint interventionPrognostic information, goals of care, and code status decision‐making among older patients
van Dyck L, Fried TR. Prognostic information, goals of care, and code status decision‐making among older patients. Journal Of The American Geriatrics Society 2021, 69: 2025-2028. PMID: 33675032, PMCID: PMC8273121, DOI: 10.1111/jgs.17080.Peer-Reviewed Original ResearchPrognosis as Health Trajectory: Educating Patients and Informing the Plan of Care
Thomas JM, Cooney LM, Fried TR. Prognosis as Health Trajectory: Educating Patients and Informing the Plan of Care. Journal Of General Internal Medicine 2021, 36: 2125-2126. PMID: 33403621, PMCID: PMC8298689, DOI: 10.1007/s11606-020-06505-7.Peer-Reviewed Original Research
2019
Communication About Treatment Options and Shared Decision Making in the Intensive Care Unit
Fried TR. Communication About Treatment Options and Shared Decision Making in the Intensive Care Unit. JAMA Internal Medicine 2019, 179: 684-685. PMID: 30933240, DOI: 10.1001/jamainternmed.2019.0034.Peer-Reviewed Original ResearchMedication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy
Fried TR, Mecca MC. Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy. Journal Of The American Geriatrics Society 2019, 67: 1123-1127. PMID: 30697698, PMCID: PMC6561813, DOI: 10.1111/jgs.15798.Peer-Reviewed Original ResearchConceptsNumber of medicationsAppropriate polypharmacyOlder adultsMedication benefitsComplex medication regimensMultiple chronic conditionsVulnerable older adultsMedication appropriatenessUnderestimate harmsInappropriate medicationsMore medicationsAdverse eventsMore observational studiesMedication regimensComplex regimenAdverse outcomesAppropriate medicationChronic conditionsMedications resultsObservational studyPolypharmacyMedicationsHealth outcomesCorrect medicationLikelihood of harm
2016
Shared Decision Making — Finding the Sweet Spot
Fried TR. Shared Decision Making — Finding the Sweet Spot. New England Journal Of Medicine 2016, 374: 104-106. PMID: 26760081, DOI: 10.1056/nejmp1510020.Peer-Reviewed Original Research
2011
Effects of Benefits and Harms on Older Persons' Willingness to Take Medication for Primary Cardiovascular Prevention
Fried TR, Tinetti ME, Towle V, O’Leary J, Iannone L. Effects of Benefits and Harms on Older Persons' Willingness to Take Medication for Primary Cardiovascular Prevention. JAMA Internal Medicine 2011, 171: 923-928. PMID: 21357797, PMCID: PMC3101287, DOI: 10.1001/archinternmed.2011.32.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAspirinCardiotonic AgentsCardiovascular DiseasesDrug-Related Side Effects and Adverse ReactionsFemaleHealth Knowledge, Attitudes, PracticeHumansInterviews as TopicMaleMyocardial InfarctionPatient CompliancePatient ParticipationPatient SelectionPharmaceutical PreparationsPrimary PreventionRisk AssessmentSurveys and QuestionnairesConceptsPrimary cardiovascular disease preventionCardiovascular disease preventionMyocardial infarctionAbsolute benefitAdverse effectsDisease preventionOlder personsCommunity-living older personsPrimary cardiovascular preventionEvidence-based guidelinesAverage risk reductionRisk reductionCardiovascular preventionAvailable medicationsPrimary preventionClinical guidelinesTreatment benefitMild fatigueMedicationsQuality assurance initiativesPerson interviewsPreventionParticipantsHarmLarge proportion
2010
Primary Care Clinicians' Experiences With Treatment Decision Making for Older Persons With Multiple Conditions
Fried TR, Tinetti ME, Iannone L. Primary Care Clinicians' Experiences With Treatment Decision Making for Older Persons With Multiple Conditions. JAMA Internal Medicine 2010, 171: 75-80. PMID: 20837819, PMCID: PMC3021478, DOI: 10.1001/archinternmed.2010.318.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedChronic DiseaseComorbidityConnecticutDecision MakingFemaleFocus GroupsGoalsHospitals, UniversityHumansMaleMedication AdherenceMiddle AgedNarrationNurse PractitionersPatient CompliancePhysician AssistantsPhysicians, Primary CarePractice Patterns, Physicians'Primary Health CareQualitative ResearchResidence CharacteristicsUnited StatesWorkforceConceptsGuideline-directed carePrimary care cliniciansTreatment decisionsOlder patientsCare cliniciansOlder personsDisease-specific guidelinesMultiple medical conditionsPrimary care practicesBetter treatment decisionsComplex regimensPatient goalsPatient prioritiesPatient's abilityClinician experienceMedical conditionsOutcome dataPatientsCare practicesVeterans AffairsMultiple conditionsCliniciansDesign of interventionsRole of specialistsMultiple diseasesElectronic health records and adverse drug events after patient transfer
Boockvar K, Livote E, Goldstein N, Nebeker J, Siu A, Fried T. Electronic health records and adverse drug events after patient transfer. BMJ Quality & Safety 2010, 19: e16. PMID: 20724395, PMCID: PMC2965207, DOI: 10.1136/qshc.2009.033050.Peer-Reviewed Original ResearchConceptsAdverse drug eventsHigh-risk medication discrepanciesElectronic health recordsMedication discrepanciesSite of careDrug eventsPatient transferStructured medical record reviewNon-VA groupsNon-VA patientsVeterans Affairs patientsHealth recordsMedical record reviewGroup of patientsPairs of physiciansHospitalisation episodesMedication reviewHospital transferOverall incidenceRecord reviewClinical covariatesMedication errorsNursing homesPatientsTime of transferRedefining the "planning" in advance care planning: preparing for end-of-life decision making.
Sudore RL, Fried TR. Redefining the "planning" in advance care planning: preparing for end-of-life decision making. Annals Of Internal Medicine 2010, 153: 256-61. PMID: 20713793, PMCID: PMC2935810, DOI: 10.7326/0003-4819-153-4-201008170-00008.Peer-Reviewed Original Research
2009
Physician factors associated with outpatient palliative care referral
Ahluwalia S, Fried T. Physician factors associated with outpatient palliative care referral. Palliative Medicine 2009, 23: 608-615. PMID: 19460830, PMCID: PMC2916731, DOI: 10.1177/0269216309106315.Peer-Reviewed Original ResearchConceptsOutpatient palliative carePalliative care programsPrimary care physiciansPalliative carePhysician factorsHealth maintenance organizationKaiser PermanenteIll patientsCare physiciansAppropriate referralCare programOutpatient palliative care referralPalliative care referralNon-profit health maintenance organizationCross-sectional studySelf-administered questionnaireCare referralPhysician characteristicsPhysicians' beliefsReferralMaintenance organizationPatientsCarePhysiciansPrior yearPrescribing discrepancies likely to cause adverse drug events after patient transfer
Boockvar K, Liu S, Goldstein N, Nebeker J, Siu A, Fried T. Prescribing discrepancies likely to cause adverse drug events after patient transfer. BMJ Quality & Safety 2009, 18: 32. PMID: 19204129, PMCID: PMC2728360, DOI: 10.1136/qshc.2007.025957.Peer-Reviewed Original ResearchConceptsAdverse drug eventsPositive predictive valueDrug classesMedication discrepanciesDrug eventsPatient transferObserved positive predictive valueHigh positive predictive valueHigh-risk patientsHigh-risk medicationsNon-opioid analgesicsNursing home patientsSite of careCertain drug classesDrug discrepanciesOpioid analgesicsDrug prescribingMedical recordsNursing homesPatientsPredictive valueCare qualityClinician ratersAnalgesicsTypes of discrepancies
2002
Understanding the Treatment Preferences of Seriously Ill Patients
Fried TR, Bradley EH, Towle VR, Allore H. Understanding the Treatment Preferences of Seriously Ill Patients. New England Journal Of Medicine 2002, 346: 1061-1066. PMID: 11932474, DOI: 10.1056/nejmsa012528.Peer-Reviewed Original ResearchConceptsBurden of treatmentTreatment preferencesAdverse outcomesCognitive impairmentChronic obstructive pulmonary diseaseLow-burden treatmentCongestive heart failureObstructive pulmonary diseaseSevere functional impairmentLimited life expectancyOutcome of treatmentAdvance care planningYears of agePercent of participantsLife-sustaining treatmentHeart failureIll patientsPulmonary diseaseQuestions patientsPatient preferencesPrimary diagnosisPatients' attitudesFunctional impairmentHigh burdenCare planning
2001
Documentation of discussions about prognosis with terminally ill patients
Bradley E, Hallemeier A, Fried T, Johnson-Hurzeler R, Cherlin E, Kasl S, Horwitz S. Documentation of discussions about prognosis with terminally ill patients. The American Journal Of Medicine 2001, 111: 218-223. PMID: 11530033, DOI: 10.1016/s0002-9343(01)00798-7.Peer-Reviewed Original ResearchConceptsIll patientsMedical recordsDocumentation of discussionInoperable lung cancerStandardized abstraction formAdvance care planningLife-sustaining treatmentEnd of lifeClinical factorsMedical chartsIll inpatientsLung cancerCommunity hospitalResuscitate ordersAbstraction formCare planningGall bladderPatientsPrognosisFuture careFamily preferencesInpatientsCancerTreatmentPrevious studiesNurses' use of palliative care practices in the acute care setting
Bradley E, Cherlin E, McCorkle R, Fried T, Kasl S, Cicchetti D, Johnson-Hurzeler R, Horwitz S. Nurses' use of palliative care practices in the acute care setting. Journal Of Professional Nursing 2001, 17: 14-22. PMID: 11211378, DOI: 10.1053/jpnu.2001.20255.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAttitude of Health PersonnelClinical CompetenceConnecticutCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHospice CareHospitals, CommunityHumansMaleNursing CareNursing Evaluation ResearchNursing Staff, HospitalPalliative CarePrognosisSurveys and QuestionnairesTerminal CareTerminally IllTruth DisclosureConceptsPalliative care practiceAcute care settingIll patientsCare practicesCare settingsGroup of nursesSelf-administered questionnaireMost nursesNurses' useHospice trainingNursesPatientsHospiceSubstantial proportionEducational preparationGreater useGreater knowledgeEducational programsSettingSubstantial gapsPrognosisHospitalYearsCare