2024
An innovative approach to aligning healthcare with what matters most to patients: A hybrid type 1 trial protocol of patient priorities care for older adults with multiple chronic conditions
Naik A, Shanahan M, Dindo L, Mecca M, Arney J, Amspoker A, Wydermyer S, Banks J, Street R, Kiefer L, Zenoni M, Rosen T, Gonzalez R, Catic A, Fried T. An innovative approach to aligning healthcare with what matters most to patients: A hybrid type 1 trial protocol of patient priorities care for older adults with multiple chronic conditions. Contemporary Clinical Trials 2024, 143: 107613. PMID: 38914308, DOI: 10.1016/j.cct.2024.107613.Peer-Reviewed Original ResearchMultiple chronic conditionsHealth priorityOlder adultsCare approachChronic conditionsTreatment burdenPriorities of older adultsPatient-centered care approachPatient Priorities CarePatients' health prioritiesPrimary care providersVeterans Affairs Medical CenterHealth care decisionsAffairs Medical CenterHigh treatment burdenComplexity of patientsRandomized controlled trialsPrimary careUsual carePriority careCare providersImplementation outcomesCare decisionsCare optionsAssessor-blinded
2019
Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy
Fried TR, Mecca MC. Medication Appropriateness in Vulnerable Older Adults: Healthy Skepticism of Appropriate Polypharmacy. Journal Of The American Geriatrics Society 2019, 67: 1123-1127. PMID: 30697698, PMCID: PMC6561813, DOI: 10.1111/jgs.15798.Peer-Reviewed Original ResearchConceptsNumber of medicationsAppropriate polypharmacyOlder adultsMedication benefitsComplex medication regimensMultiple chronic conditionsVulnerable older adultsMedication appropriatenessUnderestimate harmsInappropriate medicationsMore medicationsAdverse eventsMore observational studiesMedication regimensComplex regimenAdverse outcomesAppropriate medicationChronic conditionsMedications resultsObservational studyPolypharmacyMedicationsHealth outcomesCorrect medicationLikelihood of harm