2022
The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation
Higerd-Rusli G, Tyagi S, Liu S, Dib-Hajj F, Waxman S, Dib-Hajj S. The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation. Journal Of Biological Chemistry 2022, 299: 102816. PMID: 36539035, PMCID: PMC9843449, DOI: 10.1016/j.jbc.2022.102816.Peer-Reviewed Original ResearchConceptsMembrane proteinsIon channelsNeuronal functionDistinct neuronal compartmentsAxonal membrane proteinsRetrograde traffickingNeuronal polarityRecycling pathwayLate endosomesPlasma membraneSpecific proteinsAxonal traffickingNovel mechanismCell membraneSodium channel NaNeuronal compartmentsMultiple pathwaysLive neuronsVoltage-gated sodium channel NaProteinEndocytosisMembrane specializationsTraffickingMembraneChannel Na
1980
Coordinated micropinocytotic activity of adjacent neuronal membranes in mammalian central nervous system
Waxman S, Waxman M, Pappas G. Coordinated micropinocytotic activity of adjacent neuronal membranes in mammalian central nervous system. Neuroscience Letters 1980, 20: 141-146. PMID: 7443064, DOI: 10.1016/0304-3940(80)90136-6.Peer-Reviewed Original ResearchConceptsExocytosis/endocytosisMembrane infoldingsMammalian central nervous systemCoated invaginationsNon-synaptic sitesNeuronal membranesCell membraneCentral nervous systemCoordinated activityNervous systemMembraneInvaginationMicropinocytotic activityInfoldingsElectrotonic synapsesEndocytosisSpeciesCytoplasmTissueNumber of sitesSitesSynapsesWide varietyActivityNeighboring dendrites