2021
Reinforcement learning detuned in addiction: integrative and translational approaches
Groman SM, Thompson SL, Lee D, Taylor JR. Reinforcement learning detuned in addiction: integrative and translational approaches. Trends In Neurosciences 2021, 45: 96-105. PMID: 34920884, PMCID: PMC8770604, DOI: 10.1016/j.tins.2021.11.007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnimalsBehavior, AddictiveDecision MakingHumansReinforcement, PsychologySubstance-Related DisordersConceptsDecision-making deficitsPathophysiology of addictionDecision-making strategiesBiobehavioral mechanismsAddictionReinforcement learningDecision-making processDrug useTranslational approachComputational componentsDeficitsLearningDifferent componentsBiological mechanismsOutcomesFindingsRecent studiesBehaviorStudy
2014
Dissecting impulsivity and its relationships to drug addictions
Jentsch JD, Ashenhurst JR, Cervantes MC, Groman SM, James AS, Pennington ZT. Dissecting impulsivity and its relationships to drug addictions. Annals Of The New York Academy Of Sciences 2014, 1327: 1-26. PMID: 24654857, PMCID: PMC4360991, DOI: 10.1111/nyas.12388.Peer-Reviewed Original Research
2013
Identifying the molecular basis of inhibitory control deficits in addictions: neuroimaging in non-human primates
Groman SM, Jentsch JD. Identifying the molecular basis of inhibitory control deficits in addictions: neuroimaging in non-human primates. Current Opinion In Neurobiology 2013, 23: 625-631. PMID: 23528268, PMCID: PMC3731407, DOI: 10.1016/j.conb.2013.03.001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBehavior, AddictiveDopamineHumansInhibition, PsychologicalNeuroimagingSubstance-Related DisordersConceptsNon-human primatesSerotonin systemStimulant-dependent individualsAddiction-related behaviorsInhibitory control deficitsTreatment of addictionDopamine systemNeural alterationsAddiction liabilityNovel targetStimulant useStimulant addictionFunctional phenotypeControl deficitsHuman primatesRecent dataInhibitory controlAddictionBi-directional relationshipBiological phenotypesPrimatesPhenotype
2008
Poor response inhibition: At the nexus between substance abuse and attention deficit/hyperactivity disorder
Groman SM, James AS, Jentsch JD. Poor response inhibition: At the nexus between substance abuse and attention deficit/hyperactivity disorder. Neuroscience & Biobehavioral Reviews 2008, 33: 690-698. PMID: 18789354, PMCID: PMC2728075, DOI: 10.1016/j.neubiorev.2008.08.008.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderSubstance abuseSubstance abuse/dependenceHyperactivity disorderAnimal model studiesAbuse/dependenceAttention-deficit/hyperactivity disorderDeficit/hyperactivity disorderResponse inhibition functionDeficit hyperactivity disorderUltimate progressionDependence disordersUnderlying biological mechanismsAnimal modelsBehavioral impairmentsCingulate cortexDisordersMultiple causesExhibit deficitsADHD-like traitsDrug takingResponse inhibitionBiological mechanismsImpairmentNeural level