Orbitofrontal Circuits Control Multiple Reinforcement-Learning Processes
Groman SM, Keistler C, Keip AJ, Hammarlund E, DiLeone RJ, Pittenger C, Lee D, Taylor JR. Orbitofrontal Circuits Control Multiple Reinforcement-Learning Processes. Neuron 2019, 103: 734-746.e3. PMID: 31253468, PMCID: PMC6893860, DOI: 10.1016/j.neuron.2019.05.042.Peer-Reviewed Original ResearchBi‐directional modulation of food habit expression by the endocannabinoid system
Gianessi CA, Groman SM, Taylor JR. Bi‐directional modulation of food habit expression by the endocannabinoid system. European Journal Of Neuroscience 2019, 49: 1610-1622. PMID: 30589475, PMCID: PMC7790508, DOI: 10.1111/ejn.14330.Peer-Reviewed Original ResearchConceptsCannabinoid receptor type 1Endocannabinoid systemTransient receptor potential cationHabitual respondingExpression of habitsMale C57BL/6 miceEndocannabinoid transport inhibitor AM404Potential pharmacological strategiesSubstance use disordersReceptor type 1Bi-directional modulationC57BL/6 micePharmacological strategiesCB1 receptorsPharmacological stimulationUse disordersEnzyme inhibitorsMental disordersType 1Neural circuitsNeuromodulatory systemsGoal-directed actionsSimilar reductionAM404Habit learning