2010
Dynamic culture enhances stem cell infiltration and modulates extracellular matrix production on aligned electrospun nanofibrous scaffolds
Nerurkar NL, Sen S, Baker BM, Elliott DM, Mauck RL. Dynamic culture enhances stem cell infiltration and modulates extracellular matrix production on aligned electrospun nanofibrous scaffolds. Acta Biomaterialia 2010, 7: 485-491. PMID: 20728589, PMCID: PMC2994961, DOI: 10.1016/j.actbio.2010.08.011.Peer-Reviewed Original ResearchConceptsTissue engineering applicationsElectrospun scaffoldsNanofibrous scaffoldsEngineering applicationsFiber-reinforced soft tissuesDynamic cultureElectrospun nanofibrous scaffoldsCellular ingressSmall pore sizeDynamic culture conditionsMechanical propertiesScaffold thicknessTensile modulusFree-swelling conditionsPore sizeFree-swelling cultureHeterogeneous depositionDense packingInfiltration resultsIngressScaffoldsKnee meniscusApplicationsModulusSoft tissue
2007
Multi-Lamellar and Multi-Axial Maturation of Cell-Seeded Fiber-Reinforced Tissue Engineered Constructs
Baker B, O’Connell G, Sen S, Nathan A, Elliott D, Mauck R. Multi-Lamellar and Multi-Axial Maturation of Cell-Seeded Fiber-Reinforced Tissue Engineered Constructs. 2007, 1013-1014. DOI: 10.1115/sbc2007-176434.Peer-Reviewed Original ResearchFunctional tissue engineeringLength scalesLaminate structureCompressive loadingMultiple length scalesTensile deformationTensile propertiesCircumferential tensile propertiesTissue engineeringCentimeter length scalesFiber directionTransverse directionRadial tie fibersMechanical environmentKnee meniscusNanoscale interactionsAdjacent layersStructural propertiesCell patterningMechanical functionHorizontal axisAnnulus fibrosusMeniscusDeformationProperties