2018
Need for evidence-based early intervention programmes: a public health perspective
Guloksuz S, van Os J. Need for evidence-based early intervention programmes: a public health perspective. BMJ Mental Health 2018, 21: 128. PMID: 30282627, PMCID: PMC10270415, DOI: 10.1136/ebmental-2018-300030.Peer-Reviewed Original ResearchConceptsClinical high riskUltra-high riskPsychotic symptomsEarly intervention programsSpecific effective treatmentBroader prevention strategiesIntervention programsPositive psychotic symptomsPublic health impactPublic health perspectivePrognostic accuracyHelp-seeking populationEffective treatmentHigh riskPsychosis benefitPrevention strategiesRisk enrichmentPredictive valueTherapeutic interventionsMeta-analytical evidenceSymptomsHealth perspectiveEarly psychopathologyHealth impactsAssessment tool
2017
The slow death of the concept of schizophrenia and the painful birth of the psychosis spectrum
Guloksuz S, van Os J. The slow death of the concept of schizophrenia and the painful birth of the psychosis spectrum. Psychological Medicine 2017, 48: 229-244. PMID: 28689498, DOI: 10.1017/s0033291717001775.Peer-Reviewed Original ResearchA critique of the “ultra‐high risk” and “transition” paradigm
van Os J, Guloksuz S. A critique of the “ultra‐high risk” and “transition” paradigm. World Psychiatry 2017, 16: 200-206. PMID: 28498576, PMCID: PMC5428198, DOI: 10.1002/wps.20423.Peer-Reviewed Original ResearchClinical high riskUltra-high riskCommon mental disordersMental disordersPsychotic experiencesCHR researchHigh-risk approachMental health problemsPublic health perspectiveFalse-positive findingsTransdiagnostic expressionClinical picturePoor outcomePoor prognosisFunctional outcomeBaseline differencesHigh riskOmega-3Health problemsPositive findingsEpidemiological researchDiagnostic shiftUHR sampleYoung individualsHealth perspective