2023
The association between polygenic risk scores for mental disorders and social cognition: A scoping review
Fusar-Poli L, Rodolico A, Martinez M, Fichera C, Lin B, Basadonne I, Concerto C, Aguglia E, Guloksuz S, Signorelli M. The association between polygenic risk scores for mental disorders and social cognition: A scoping review. Journal Of Psychiatric Research 2023, 164: 389-401. PMID: 37418886, DOI: 10.1016/j.jpsychires.2023.06.029.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial cognitionMental disordersAttention deficit hyperactivity disorderReal-world functioningSC deficitsEmotion recognitionHyperactivity disorderSpectrum disorderPresent impairmentsPolygenic risk scoresCognitionFuture researchMolecular genetic riskSignificant difficultiesSpecific disordersDisordersUnaffected relativesGenetic riskRisk scorePeopleUnderstanding of mechanismsFunctioningEnvironmental risk factorsScoresExamining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study
Fusar-Poli L, Prachason T, Erzin G, Pries L, Brondino N, Politi P, Delespaul P, Kenis G, Luykx J, Lin B, Richards A, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran E, Kaymak S, Mihaljevic M, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz P, García-Portilla M, Sanjuan J, Escarti M, Santos J, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric N, Atbaşoğlu C, Üçok A, Alptekin K, Saka M, Arango C, O'Donovan M, van Os J, Rutten B, Guloksuz S, investigators G. Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study. Psychiatry Research 2023, 323: 115184. PMID: 37015164, DOI: 10.1016/j.psychres.2023.115184.Peer-Reviewed Original ResearchConceptsBenton Facial Recognition TestDegraded Facial Affect Recognition TaskWechsler Adult Intelligence Scale-Third EditionSchizophrenia spectrum disordersSocial cognitionCognitive domainsFacial affect recognition taskAffect recognition taskFacial Recognition TestCognitive impairmentRecognition testSpectrum disorderRecognition taskCross-sectional sampleHealthy controlsCognitionPsychosis spectrumShort versionUnaffected siblingsNeurocognitionEUGEI studySchizophreniaPerceptionImpairmentSiblingsExamining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Findings from the EUGEI study
Fusar-Poli L, Investigators E, Investigators G, van Os J, Rutten B, Guloksuz S. Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Findings from the EUGEI study. European Psychiatry 2023, 66: s445-s445. PMCID: PMC10434418, DOI: 10.1192/j.eurpsy.2023.957.Peer-Reviewed Original ResearchWechsler Adult Intelligence ScaleSchizophrenia spectrum disordersSocial cognitionFacial emotion recognition taskUnaffected siblingsEmotion recognition taskAdult Intelligence ScaleDisclosure of interestCognitive domainsIntelligence ScaleSpectrum disorderRecognition taskCognitionHealthy controlsNeurocognitionLongitudinal studyPresent cross-sectional studyEUGEI studyMolecular genetic riskSchizophrenia
2021
Longitudinal clinical and functional outcome in distinct cognitive subgroups of first-episode psychosis: a cluster analysis
Oomen P, Begemann M, Brand B, de Haan L, Veling W, Koops S, van Os J, Smit F, Bakker P, van Beveren N, Boonstra N, Gülöksüz S, Kikkert M, Lokkerbol J, Marcelis M, Rosema B, de Beer F, Gangadin S, Geraets C, van ‘t Hag E, Haveman Y, van der Heijden I, Voppel A, Willemse E, van Amelsvoort T, Bak M, Batalla A, Been A, van den Bosch M, van den Brink T, Faber G, Grootens K, de Jonge M, Knegtering R, Kurkamp J, Mahabir A, Pijnenborg G, Staring T, Veen N, Veerman S, Wiersma S, Graveland E, Hoornaar J, Sommer I. Longitudinal clinical and functional outcome in distinct cognitive subgroups of first-episode psychosis: a cluster analysis. Psychological Medicine 2021, 53: 2317-2327. PMID: 34664546, PMCID: PMC10123843, DOI: 10.1017/s0033291721004153.Peer-Reviewed Original ResearchConceptsDistinct cognitive subgroupsCognitive subgroupsFirst-episode psychosisDiscrete cognitive profilesGeneral functioningTrend-level effectsCognitive profileSelf-reported functional outcomesCognitive clustersCognitive deficitsCognitionBrief assessmentFunctional outcomeLarge sampleFEP patientsClinical outcomesCurrent resultsSevere clinical symptomsPsychosisEarly identificationHealthy controlsCluster analysisClinical symptomsFunctioningDeficits
2018
Recurrent Neural Networks in Mobile Sampling and Intervention
Koppe G, Guloksuz S, Reininghaus U, Durstewitz D. Recurrent Neural Networks in Mobile Sampling and Intervention. Schizophrenia Bulletin 2018, 45: 272-276. PMID: 30496527, PMCID: PMC6403085, DOI: 10.1093/schbul/sby171.Peer-Reviewed Original ResearchConceptsRecurrent neural networkEcological momentary interventionsEveryday life contextPsychological processesMomentary interventionsData modalitiesDifferent data modalitiesSocial outcomesSocioenvironmental factorsFuture researchMultiple data modalitiesNeural networkTreatment of psychosisOnline feedbackIndividual trajectoriesPsychosisDaily lifeContext-specific interventionsInterventionEmotionsCognitionExperienceStatistical machineContextFitness trackers