2012
Network Meta-analysis of Margin Threshold for Women With Ductal Carcinoma In Situ
Wang SY, Chu H, Shamliyan T, Jalal H, Kuntz KM, Kane RL, Virnig BA. Network Meta-analysis of Margin Threshold for Women With Ductal Carcinoma In Situ. Journal Of The National Cancer Institute 2012, 104: 507-516. PMID: 22440677, PMCID: PMC3916966, DOI: 10.1093/jnci/djs142.Peer-Reviewed Original ResearchConceptsIpsilateral breast tumor recurrenceBreast-conserving surgeryRisk of IBTRNegative marginsPositive marginsDuctal carcinomaOdds ratioBreast tumor recurrenceNegative surgical marginsNetwork Meta-AnalysisMixed treatment comparisonMargin thresholdIBTR eventsDCIS patientsMargin statusSurgical marginsTumor recurrenceMeta-regression techniquesReduced riskLower riskPatientsPubMed databaseCosmetic constraintsMeta-AnalysisRadiotherapy
2010
Incorporating margin status information in treatment decisions for women with ductal carcinoma in situ: a decision analysis
Wang SY, Kuntz K, Tuttle T, Kane R. Incorporating margin status information in treatment decisions for women with ductal carcinoma in situ: a decision analysis. Breast Cancer Research And Treatment 2010, 124: 393-402. PMID: 20848183, DOI: 10.1007/s10549-010-1166-7.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingDecision Support TechniquesFemaleHumansMarkov ChainsMastectomy, SegmentalMiddle AgedNeoplasm Recurrence, LocalPatient PreferencePatient SelectionQuality-Adjusted Life YearsRadiotherapy, AdjuvantRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsBreast-conserving surgeryQuality-adjusted life yearsRadiation therapyMargin statusDuctal carcinomaRT side effectsDecision-analytic Markov modelOne-way sensitivity analysesImportance of patientsProbabilistic sensitivity analysesDCIS treatmentInvasive recurrenceSalvage mastectomyOptimal treatmentHypothetical cohortTreatment decisionsLifetime horizonSide effectsLife yearsDCISPatientsWomenCarcinomaTreatment