Data-driven insights into neighborhood adherence to cancer prevention guidelines in Philadelphia
DuBois T, Moore K, Rollins H, Silbaugh J, Sorice K, Lynch S. Data-driven insights into neighborhood adherence to cancer prevention guidelines in Philadelphia. PLOS ONE 2024, 19: e0313334. PMID: 39565787, PMCID: PMC11578512, DOI: 10.1371/journal.pone.0313334.Peer-Reviewed Original ResearchConceptsCancer prevention guidelinesAdherence to cancer prevention guidelinesCancer mortalityGuideline adherencePrevention guidelinesPhysical activityLow cancer screening ratesAmerican Cancer Society guidelinesLow adherenceCancer prevention recommendationsCancer screening ratesLower guideline adherenceHighest cancer burdenBehavioral risk factorsPublic health officialsScreening ratesExcessive alcohol consumptionPreventive servicesCancer burdenPoor healthRecommendation adherencePrevention recommendationsHealthy livingCancer casesModify riskAn exploratory analysis of the impact of area-level exposome on geographic disparities in aggressive prostate cancer
Wiese D, DuBois T, Sorice K, Fang C, Ragin C, Daly M, Reese A, Henry K, Lynch S. An exploratory analysis of the impact of area-level exposome on geographic disparities in aggressive prostate cancer. Scientific Reports 2024, 14: 16900. PMID: 39075110, PMCID: PMC11286755, DOI: 10.1038/s41598-024-63726-0.Peer-Reviewed Original ResearchConceptsSocial determinants of health domainsElevated oddsTract-level povertyAggressive prostate cancer casesExposome researchDesign targeted interventionsAssociated with raceAggressive prostate cancerSocial determinantsCancer burdenHealth domainsGeographic disparitiesLocal cancer burdenHealth insuranceLogistic regressionExposome factorsAssociation studiesRisk factorsOddsResidential locationExposomeGeographical areasExploratory analysisProstate cancerHealthGeographic Disparities in Cancer Incidence in the US Population Aged 20 to 49 Years, 2016–2020
DuBois T, Henry K, Siegel S, Lynch S. Geographic Disparities in Cancer Incidence in the US Population Aged 20 to 49 Years, 2016–2020. Preventing Chronic Disease 2024, 21: e32. PMID: 38723272, PMCID: PMC11086694, DOI: 10.5888/pcd21.230335.Peer-Reviewed Original ResearchFactors Associated With Racial and Ethnic Disparities in Locally Advanced Rectal Cancer Outcomes
Shulman R, Deng M, Handorf E, Meyer J, Lynch S, Arora S. Factors Associated With Racial and Ethnic Disparities in Locally Advanced Rectal Cancer Outcomes. JAMA Network Open 2024, 7: e240044. PMID: 38421650, PMCID: PMC10905315, DOI: 10.1001/jamanetworkopen.2024.0044.Peer-Reviewed Original ResearchConceptsPathological complete responseLocally advanced rectal cancerSocial determinants of healthRate of pathological complete responseNon-Hispanic Black patientsNon-Hispanic white patientsDeterminants of healthNational Cancer DatabaseNeoadjuvant therapyPN0 statusTumor downstagingSocial determinantsEthnic disparitiesRectal cancerCancer DatabaseRates of tumor downstagingWhite patientsLymph node-positive diseaseNon-Hispanic black raceTreatment outcomesBlack patientsAssociated with treatment responseNon-Hispanic blacksNon-Hispanic whitesNode-positive disease