2021
Specific HLA alleles, paired with TCR V- and J-gene segment usage, link to distinct multiple myeloma survival rates
Huda TI, Mihyu M, Gozlan EC, Arndt MF, Diaz MJ, Zaman S, Chobrutskiy BI, Blanck G. Specific HLA alleles, paired with TCR V- and J-gene segment usage, link to distinct multiple myeloma survival rates. Leukemia & Lymphoma 2021, 62: 1711-1720. PMID: 33622167, DOI: 10.1080/10428194.2021.1885655.Peer-Reviewed Original ResearchConceptsHLA allele combinationsTCR VBlood samplesSurvival rateT cell receptor VOverall survival rateT cell characterizationSpecific HLA allelesLarger patient setsDistinct overall survival ratesSolid tumor typesSurvival distinctionsMM cohortHLA allelesJ-gene segment usageTumor typesPotential associationImmunogenomics studiesHLASegment usagePatient setAllele combinationsTCR recombinationImmunogenetic parametersImmunogenomic data
2020
Unproductive T cell receptor-β and T cell receptor-δ recombination recoveries in tissue and blood samples are associated with improved survival outcomes for uterine and ovarian cancers
Zaman S, Koohestani D, Diviney A, Chobrutskiy B, Arndt M. Unproductive T cell receptor-β and T cell receptor-δ recombination recoveries in tissue and blood samples are associated with improved survival outcomes for uterine and ovarian cancers. Gynecologic Oncology 2020, 159: 204. DOI: 10.1016/j.ygyno.2020.05.327.Peer-Reviewed Original Research