2024
Retinal integrity in human babesiosis: a pilot study
Dionne E, Adelman R, Cekic O, Golden M, Moffarah A, Krause P, Farhadian S. Retinal integrity in human babesiosis: a pilot study. BMC Ophthalmology 2024, 24: 310. PMID: 39048971, PMCID: PMC11267664, DOI: 10.1186/s12886-024-03568-6.Peer-Reviewed Original ResearchConceptsEvidence of retinopathyNo study patientRetina of patientsCohort of patientsAbnormal vessel formationComplication of babesiosisRetinal tearsRetinal inflammationRetinal eye examResultsTen patientsRetinal integrityRetinal examinationRetinal bleedingIndirect ophthalmoscopeRetinal abnormalitiesStudy patientsChart reviewCase reportEye examPilot studyPatientsAnimal studiesSmall studyClinical informationHuman babesiosis
2021
HEMORRHAGIC OCCLUSIVE RETINAL VASCULITIS AFTER INTRACAMERAL VANCOMYCIN USE IN CATARACT SURGERY AFTER INTRAVENOUS EXPOSURE
Alasil T, Wong JJY, Adelman RA, Tom D, Coady PA. HEMORRHAGIC OCCLUSIVE RETINAL VASCULITIS AFTER INTRACAMERAL VANCOMYCIN USE IN CATARACT SURGERY AFTER INTRAVENOUS EXPOSURE. Retinal Cases & Brief Reports 2021, Publish Ahead of Print: &na;. PMID: 29474222, DOI: 10.1097/icb.0000000000000725.Peer-Reviewed Original ResearchConceptsHemorrhagic occlusive retinal vasculitisOcclusive retinal vasculitisCataract surgeryLeft eyeIntracameral vancomycinRetinal vasculitisSystemic vancomycinHypersensitivity reactionsPan-retinal photocoagulationPeripheral retinal hemorrhagesFavorable visual outcomeUncomplicated cataract surgeryOral prednisoneFundus examinationRetinal ischemiaVisual outcomeFellow eyesInfection prophylaxisRetinal hemorrhagesBlurry visionVisual acuityAnterior chamberIntraocular lensIschemic areaVasculitis cases
2020
VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two.
Soliman MK, Gini G, Kuhn F, Parolini B, Ozdek S, Adelman RA, Sallam AB. VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two. Retina 2020, 41: 423-430. PMID: 32467482, DOI: 10.1097/iae.0000000000002856.Peer-Reviewed Original ResearchConceptsIntravitreal antibioticsPPV groupEarly PPVVisual outcomeRetinal detachmentPostintravitreal injection endophthalmitisRetrospective multicenter cohortFinal visual acuityWeeks of presentationDays of presentationMethod of treatmentEarly vitrectomyMulticenter cohortIntravitreal injectionPlana vitrectomyRetina specialistsVisual acuityMean ageIntraocular proceduresEndophthalmitisSimilar outcomesLight perceptionEyesVitrectomyOutcomesNational Trends in the United States Eye Care Workforce from 1995 to 2017
Feng PW, Ahluwalia A, Feng H, Adelman RA. National Trends in the United States Eye Care Workforce from 1995 to 2017. American Journal Of Ophthalmology 2020, 218: 128-135. PMID: 32445703, DOI: 10.1016/j.ajo.2020.05.018.Peer-Reviewed Original ResearchConceptsEye care workforceOphthalmologist densityYears of ageRural countiesEye care providersArea Health Resource FileCare workforceCross-sectional studyHealth care infrastructureRatio of ophthalmologistsMAIN OUTCOMECare providersMean annual increaseOphthalmologistsNumber of providersOptometristsCare infrastructureHealth insuranceResource FileYoung ophthalmologistsNational trendsCounty characteristicsGreater proportionAgeMetropolitan counties
2019
Age-Related Macular Degeneration Preferred Practice Pattern®
Flaxel CJ, Adelman RA, Bailey ST, Fawzi A, Lim JI, Vemulakonda GA, Ying GS. Age-Related Macular Degeneration Preferred Practice Pattern®. Ophthalmology 2019, 127: p1-p65. PMID: 31757502, DOI: 10.1016/j.ophtha.2019.09.024.Peer-Reviewed Original ResearchAcademies and InstitutesAgedAngiogenesis InhibitorsColoring AgentsFemaleFluorescein AngiographyHumansIndocyanine GreenIntravitreal InjectionsLaser CoagulationMacular DegenerationMaleOphthalmologyPractice Patterns, Physicians'Quality of Health CareTomography, Optical CoherenceUnited StatesVascular Endothelial Growth Factor AInternational Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis European Vitreo-Retinal Society Endophthalmitis Study Report 1
Soliman MK, Gini G, Kuhn F, Iros M, Parolini B, Ozdek S, Michalewska Z, Bopp S, Adelman RA, Sallam AB, Group E, Kardaszewska A, Zindamoyen A, Banker A, Serhiienko A, Loo A, Meireles A, Aydin B, Luebke B, Özmen C, Odrobina D, Bertelli E, Unsal E, Kenneth F, Becquet F, Hamon F, Pellegrini G, Tosi G, Donvito G, Khaqan H, Badat I, Fiser I, Michalewski J, Le Rouic J, Nawrocki J, Zarallo-Gallardo J, Lee J, Boninska K, Nowomiejska K, Dziegielewski K, Arrevola L, Lytvynchuk L, Elshafei M, Pietras-Trzpiel M, Irós M, Detjen M, Iglicki M, Badino M, Angelina M, Gavura M, Hasanreisoğlu M, Karadaş M, Atienza N, Acar N, Okonkwo O, Miesbauer P, Malgorzata P, Velez-Montoya R, Robert R, Frisina R, Soyeur R, Rejdak R, Giannini R, Mittal S, Saidkasimova S, Abdulsalam S, Cisiecki S, Rusnak S, Teoh S, Teixeira S, Altan T, Schrader W, Kapran Z, Aktas Z, Szijártó Z. International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis European Vitreo-Retinal Society Endophthalmitis Study Report 1. Ophthalmology Retina 2019, 3: 461-467. PMID: 31043364, DOI: 10.1016/j.oret.2019.03.009.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiogenesis InhibitorsAnti-Bacterial AgentsAntibiotic ProphylaxisCataract ExtractionDisease ManagementEndophthalmitisEuropeEye Infections, BacterialFemaleFollow-Up StudiesHumansIncidenceIntravitreal InjectionsMaleMiddle AgedOphthalmologyPractice Guidelines as TopicRetrospective StudiesSocieties, MedicalSurgical Wound InfectionVitrectomyConceptsEarly pars plana vitrectomyPars plana vitrectomyIntravitreal injectionIntravitreal antibioticsAcute endophthalmitisPlana vitrectomyIntraocular surgeryCataract surgeryPractice patternsAbsence of endophthalmitisSecond intravitreal injectionSecondary lens implantationProportion of eyesInternational practice patternsAcute postoperativeSystemic steroidsIntravitreal steroidsLens implantationAdjunctive therapySystemic antibioticsPostinjection endophthalmitisMulticenter studyRetina specialistsTherapeutic regimensVitreous opacification
2017
Vitrectomy in the management of diabetic macular edema in treatment-naïve patients
Michalewska Z, Stewart MW, Landers MB, Bednarski M, Adelman RA, Nawrocki J. Vitrectomy in the management of diabetic macular edema in treatment-naïve patients. Canadian Journal Of Ophthalmology 2017, 53: 402-407. PMID: 30119796, DOI: 10.1016/j.jcjo.2017.10.011.Peer-Reviewed Original ResearchConceptsTreatment-naïve diabetic macular edemaDiabetic macular edemaCentral retinal thicknessPars plana vitrectomyMacular edemaVisual acuityPlana vitrectomyMean central retinal thicknessDuration of diabetesProspective randomized trialsTreatment-naïve patientsInitial visual acuityVisual acuity changesPrimary outcome measureEfficacy of vitrectomyElectronic medical recordsEarly vitrectomyIntravitreal bevacizumabFinal BCVAMean BCVAPrimary endpointRetinal thicknessConsecutive patientsRandomized trialsRetrospective studyASSOCIATION BETWEEN THE VITREOMACULAR INTERFACE AND OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS IN WET AGE-RELATED MACULAR DEGENERATION
Ashraf M, Souka A, Adelman RA. ASSOCIATION BETWEEN THE VITREOMACULAR INTERFACE AND OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS IN WET AGE-RELATED MACULAR DEGENERATION. Retina 2017, 37: 1738-1745. PMID: 28005632, DOI: 10.1097/iae.0000000000001423.Peer-Reviewed Original ResearchConceptsType 1 choroidal neovascularizationChoroidal thicknessChoroidal neovascularizationWet AMDVitreomacular adhesionDry AMDVitreomacular interfaceMacular degenerationRetrospective observational cross-sectional studyOptical coherence tomography examinationObservational cross-sectional studyAge-related macular degenerationType of CNVPaired-eye studyMean choroidal thicknessCross-sectional studySignificant differencesOptical coherence tomographyWet AgeSubgroup analysisTomography examinationHeidelberg SpectralisPatientsCoherence tomographyDegeneration characteristic
2016
Trends of Anti-Vascular Endothelial Growth Factor Use in Ophthalmology Among Privately Insured and Medicare Advantage Patients
Parikh R, Ross JS, Sangaralingham LR, Adelman RA, Shah ND, Barkmeier AJ. Trends of Anti-Vascular Endothelial Growth Factor Use in Ophthalmology Among Privately Insured and Medicare Advantage Patients. Ophthalmology 2016, 124: 352-358. PMID: 27890437, DOI: 10.1016/j.ophtha.2016.10.036.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngiogenesis InhibitorsBevacizumabCohort StudiesDatabases, FactualDiabetic RetinopathyDrug UtilizationFemaleHumansInsurance, HealthIntravitreal InjectionsMacular DegenerationMaleMedicare Part CMiddle AgedOphthalmologyPrivate SectorRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetinal Vein OcclusionRetrospective StudiesUnited StatesVascular Endothelial Growth Factor AYoung AdultConceptsAge-related macular degenerationDiabetic retinal diseaseAnti-VEGF injectionsIntravitreal anti-VEGF injectionsRetinal vein occlusionAdministrative claims dataRetinal diseasesOphthalmic diseasesVein occlusionClaims dataUse of bevacizumabCurrent Procedural Terminology codesPatients 18 yearsRetrospective cohort studyMedicare Advantage patientsOptumLabs Data WarehouseDrug Administration approvalProcedural Terminology codesGrowth factor useRanibizumab useBevacizumab useAvailable medicationsCohort studyMedication useCommon medicationsHyperacuity Exam Screens for Choroidal Neovascularization in Age-Related Macular Degeneration on a Mobile Device.
Chen JS, Adelman RA. Hyperacuity Exam Screens for Choroidal Neovascularization in Age-Related Macular Degeneration on a Mobile Device. Ophthalmic Surgery Lasers And Imaging Retina 2016, 47: 708-15. PMID: 27548447, DOI: 10.3928/23258160-20160808-03.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChoroidChoroidal NeovascularizationComputers, HandheldCross-Sectional StudiesEquipment DesignFemaleFluorescein AngiographyFundus OculiHumansMacular DegenerationMaleMiddle AgedMobile ApplicationsMonitoring, PhysiologicReproducibility of ResultsTomography, Optical CoherenceVisual AcuityConceptsAge-related macular degenerationChoroidal neovascularizationMacular degenerationSpectral-domain optical coherence tomographySingle-center studyProgression of diseaseOptical coherence tomographyChart reviewTimely treatmentPatientsCoherence tomographyNeovascularizationPatient informationSame dayTreatmentPotential screenFurther dataHuman Research Protection ProgramDegenerationSubspecialistsDiseaseProgression
2015
TEMPORAL INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE VERSUS CLASSIC INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE
Michalewska Z, Michalewski J, Dulczewska-Cichecka K, Adelman RA, Nawrocki J. TEMPORAL INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE VERSUS CLASSIC INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE. Retina 2015, 35: 1844-1850. PMID: 25946691, DOI: 10.1097/iae.0000000000000555.Peer-Reviewed Original ResearchConceptsILM flap techniqueFlap techniqueMacular holeGroup BGroup AOptic nerve fiber layer appearanceProspective comparative interventional studyFinal visual acuityINTERNAL LIMITING MEMBRANE FLAPIdiopathic macular holeNumber of patientsComparative interventional studyStage IV macular holesInternal Limiting MembranePostoperative examinationConsecutive eyesVisual acuityInterventional studyTemporal sideGroup A.ILM flapTreatment groupsMembrane flapSatisfactory outcomeLimiting MembraneCHOROIDAL THICKNESS MEASURED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY BEFORE AND AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR IDIOPATHIC EPIRETINAL MEMBRANES
Michalewska Z, Michalewski J, Adelman RA, Zawilak E, Nawrocki J. CHOROIDAL THICKNESS MEASURED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY BEFORE AND AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR IDIOPATHIC EPIRETINAL MEMBRANES. Retina 2015, 35: 487-491. PMID: 25322467, DOI: 10.1097/iae.0000000000000350.Peer-Reviewed Original ResearchConceptsIdiopathic epiretinal membraneOuter choroidoscleral boundaryChoroidal thicknessFellow eyesEpiretinal membraneMembrane peelingINTERNAL LIMITING MEMBRANE PEELINGPatient's fellow eyeUnaffected fellow eyesPars plana vitrectomyChoroidal thickness measurementsRetinal pigment epitheliumSource optical coherence tomographyOptical coherence tomographySuprachoroidal layerOperated eyesRetinal arteryPlana vitrectomyProspective studyERM removalPigment epitheliumHyperreflective bandSource optical coherence tomography imagesCoherence tomographySuprachoroidal space
2013
Prevalence of Ocular Manifestations of HIV/AIDS in the Highly Active Antiretroviral Therapy (HAART) Era: A Different Spectrum in Central South China
Luo J, Jing D, Kozak I, Huiming Z, Siying C, Yezhen Y, xin Q, Luosheng T, Adelman RA, Forster SH. Prevalence of Ocular Manifestations of HIV/AIDS in the Highly Active Antiretroviral Therapy (HAART) Era: A Different Spectrum in Central South China. Ophthalmic Epidemiology 2013, 20: 170-175. PMID: 23713918, DOI: 10.3109/09286586.2013.789530.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntiretroviral Therapy, Highly ActiveAsian PeopleCD4 Lymphocyte CountCD4-Positive T-LymphocytesChildChinaCross-Sectional StudiesCytomegalovirus RetinitisEye Infections, ViralFemaleHIV InfectionsHumansMaleMiddle AgedPrevalenceRetinal DiseasesRisk FactorsVisual AcuityYoung AdultConceptsHIV/AIDSOcular manifestationsActive antiretroviral therapy (HAART) eraHuman immunodeficiency virus/Antiretroviral therapy eraActive antiretroviral therapyRoutine ophthalmic examinationEra of HAARTPrevalence of HIVCross-sectional studyHIV retinopathyTherapy eraAntiretroviral therapyCommon HIVCytomegalovirus retinitisOcular complicationsOcular examinationOcular findingsImmunodeficiency syndromeOcular lesionsOphthalmic examinationVirus/Epidemiologic studiesHigh riskOcular diseases
2012
Effects of Music Therapy on Intravitreal Injections: A Randomized Clinical Trial
Chen X, Seth RK, Rao VS, Huang JJ, Adelman RA. Effects of Music Therapy on Intravitreal Injections: A Randomized Clinical Trial. Journal Of Ocular Pharmacology And Therapeutics 2012, 28: 414-419. PMID: 22506884, DOI: 10.1089/jop.2011.0257.Peer-Reviewed Original ResearchConceptsMusic therapy groupIntravitreal injectionTherapy groupControl groupOutpatient settingClinical trialsMusic therapyFuture injectionsRandomized clinical trialsMain outcome measuresPost-procedure questionnaireSpielberger State-Trait Anxiety InventorySTAI-S scoresState-Trait Anxiety InventoryTrait Anxiety InventoryRetina clinicMost patientsPain QuestionnaireSafe interventionSubjective painOutcome measuresPatientsPainTherapyGreater decreaseIs Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy?
Prescott CR, Sklar CA, Lesser RL, Adelman RA. Is Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy? Journal Of Neuro-Ophthalmology 2012, 32: 51-53. PMID: 22269947, DOI: 10.1097/wno.0b013e318240596e.Peer-Reviewed Original ResearchConceptsNonarteritic anterior ischemic optic neuropathyAnterior ischemic optic neuropathyIschemic optic neuropathyVisual acuityIntravitreal bevacizumabOptic neuropathyTreatment optionsIntravitreal bevacizumab injectionEffective treatment optionVisual field defectsBevacizumab injectionFellow eyesClinical outcomesRetrospective studyTreatment modalitiesNatural courseField defectsPatientsDecreased acuitySmall seriesAcuityBevacizumabProfound lossVisual fieldNeuropathy
2010
Inverted Internal Limiting Membrane Flap Technique for Large Macular Holes
Michalewska Z, Michalewski J, Adelman RA, Nawrocki J. Inverted Internal Limiting Membrane Flap Technique for Large Macular Holes. Ophthalmology 2010, 117: 2018-2025. PMID: 20541263, DOI: 10.1016/j.ophtha.2010.02.011.Peer-Reviewed Original ResearchConceptsLarge macular holesILM flap techniqueMacular hole closureMembrane flap techniqueMacular holeGroup 2Group 1Visual acuityFlap techniqueOptical coherence tomographySpectral optical coherence tomographyAnatomic outcomesHole closureStandard macular hole surgeryInternal Limiting Membrane Flap TechniqueCoherence tomographyVisual acuity 12 monthsPars plana vitrectomyMacular hole surgeryFluid-air exchangeLimited visual acuityRetinal pigment epitheliumSurgical failureFoveal anatomyPlana vitrectomyPersistent Ocular Hypertension Following Intravitreal Bevacizumab and Ranibizumab Injections
Adelman RA, Zheng Q, Mayer HR. Persistent Ocular Hypertension Following Intravitreal Bevacizumab and Ranibizumab Injections. Journal Of Ocular Pharmacology And Therapeutics 2010, 26: 105-110. PMID: 20187807, DOI: 10.1089/jop.2009.0076.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabDrug Administration ScheduleDrug Therapy, CombinationFemaleHumansInjections, IntraocularIntraocular PressureMacular DegenerationMaleOcular HypertensionRanibizumabRetrospective StudiesTime FactorsVascular Endothelial Growth Factor AVitreous BodyConceptsAge-related macular degenerationPersistent ocular hypertensionOcular hypertensionIntraocular pressureIntravitreal bevacizumabRanibizumab injectionsIntravitreal injectionPrevious diagnosisGlaucoma/ocular hypertensionIntravitreal anti-VEGF injectionsAnti-VEGF injectionsIntravitreal bevacizumab injectionPostinjection intraocular pressurePreinjection intraocular pressureMultiple intravitreal injectionsTertiary referral centerRetrospective case seriesElevated intraocular pressureBevacizumab injectionIntravitreal ranibizumabReferral centerCase seriesVEGF injectionIOP increaseYAG capsulotomy
2009
A study of macular hole formation by serial spectral optical coherence tomography
Michalewska Z, Michalewski J, Sikorski BL, Kałużny J, Wojtkowski M, Adelman RA, Nawrocki J. A study of macular hole formation by serial spectral optical coherence tomography. Clinical And Experimental Ophthalmology 2009, 37: 373-383. PMID: 19594564, DOI: 10.1111/j.1442-9071.2009.02041.x.Peer-Reviewed Original Research
2008
Correlation between foveal structure and visual outcome following macular hole surgery: a spectral optical coherence tomography study
Michalewska Z, Michalewski J, Cisiecki S, Adelman R, Nawrocki J. Correlation between foveal structure and visual outcome following macular hole surgery: a spectral optical coherence tomography study. Graefe's Archive For Clinical And Experimental Ophthalmology 2008, 246: 823-830. PMID: 18386040, DOI: 10.1007/s00417-007-0764-5.Peer-Reviewed Original ResearchConceptsMacular hole surgerySpectral optical coherence tomographyHole surgeryRetinal layersGood postoperative visual acuityOptical coherence tomography studyNerve fiber layer defectsFull-thickness macular holeNormal foveal thicknessPostoperative visual acuityFinal functional outcomeOuter retinal layersPars plana vitrectomyMacular hole closurePhotoreceptor layer defectsPhotoreceptor defectsOptical coherence tomographyLayer defectsFoveal thicknessRetinal thicknessVisual outcomePlana vitrectomyVisual acuityFunctional outcomeTrypan blue staining
2006
Surgical Management of Pseudophakic Retinal Detachments A Meta-analysis
Arya AV, Emerson JW, Engelbert M, Hagedorn CL, Adelman RA. Surgical Management of Pseudophakic Retinal Detachments A Meta-analysis. Ophthalmology 2006, 113: 1724-1733. PMID: 17011954, DOI: 10.1016/j.ophtha.2006.05.044.Peer-Reviewed Original ResearchConceptsPseudophakic retinal detachmentPars plana vitrectomyUncomplicated pseudophakic retinal detachmentsFinal visual outcomeRetinal detachmentFunctional success rateScleral buckleVisual outcomeSurgical interventionPrimary failureSuccess rateStudy characteristicsInitial reattachment rateAnatomical success rateInitial surgical interventionPrimary surgical interventionCross-reference searchPreoperative evaluationSurgical managementSurgical treatmentPlana vitrectomyPneumatic retinopexyReattachment ratePooled analysisStudy protocol