1993
Skin-Selective Lymphocyte Homing Mechanisms in the Pathogenesis of Leukemic Cutaneous T-Cell Lymphoma
Heald P, Yan S, Edelson R, Tigelaar R, Picker L. Skin-Selective Lymphocyte Homing Mechanisms in the Pathogenesis of Leukemic Cutaneous T-Cell Lymphoma. Journal Of Investigative Dermatology 1993, 101: 222-226. PMID: 7688404, DOI: 10.1111/1523-1747.ep12364814.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAntigens, Differentiation, T-LymphocyteAntigens, NeoplasmCell Adhesion MoleculesEpitopesE-SelectinHumansLeukemia-Lymphoma, Adult T-CellLeukocyte Common AntigensLymphoma, T-Cell, CutaneousMembrane GlycoproteinsReceptors, Antigen, T-CellReceptors, Lymphocyte HomingSkin NeoplasmsT-LymphocytesConceptsCutaneous T-cell lymphomaT-cell lymphomaCutaneous lymphocyte antigenLymphocyte antigenT cellsErythrodermic cutaneous T-cell lymphomaLeukemic cutaneous T-cell lymphomaCutaneous T-cell lymphoma patientsSkin-associated lymphoid tissueT-cell lymphoma patientsTwo-color flow cytometryCutaneous host defenseT cells trafficMemory T cellsT cell subsetsCell surface phenotypeErythrodermic patientsLymphoma patientsPatient groupInflamed skinLymphoid tissueHoming receptorMalignant cloneLymphomaMalignant cells
1990
Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion.
Gocinski B, Tigelaar R. Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. The Journal Of Immunology 1990, 144: 4121-8. PMID: 1971294, DOI: 10.4049/jimmunol.144.11.4121.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAntigens, Differentiation, T-LymphocyteCD4-Positive T-LymphocytesCD8 AntigensDermatitis, ContactDose-Response Relationship, ImmunologicHypersensitivity, DelayedImmunity, CellularMiceT-LymphocytesConceptsEffector cellsVivo depletionBALB/c miceEffector roleCS effector cellsMonoclonal antibody depletionMurine contact sensitivityDepletion of CD4Depletion of CD8Contact sensitivity responseRole of CD4Activity of CD8Delayed-type hypersensitivityT cell subsetsCutaneous hypersensitivity responseT-cell phenotypeImportant effector roleSubsequent flow cytometric analysisFlow cytometric analysisEnhanced earImmune lymphResidual CD4Adoptive transferSuppressor cellsDistinct CD4
1988
γδ Antigen receptors of Thy-1 + dendritic epidermal cells: Implications for thymic differentiation
Allison J, Hayran W, Asarnow D, Tigelaar R, Tucker P, Bonyhadi M. γδ Antigen receptors of Thy-1 + dendritic epidermal cells: Implications for thymic differentiation. Immunologic Research 1988, 7: 292. PMID: 2906352, DOI: 10.1007/bf02935534.Peer-Reviewed Original ResearchAnimalsAntigens, Differentiation, T-LymphocyteAntigens, SurfaceBase SequenceCD3 ComplexCell DifferentiationDendritic CellsDNAGene Expression RegulationGene Rearrangement, gamma-Chain T-Cell Antigen ReceptorGene Rearrangement, T-LymphocyteMiceReceptors, Antigen, T-CellReceptors, Antigen, T-Cell, gamma-deltaThy-1 AntigensT-Lymphocytes
1987
Regulation of T-cell receptor γ-chain RNA expression in murine Thy-1+ dendritic epidermal cells
Kuziel W, Takashima A, Bonyhadi M, Bergstresser P, Allison J, Tigelaar R, Tucker P. Regulation of T-cell receptor γ-chain RNA expression in murine Thy-1+ dendritic epidermal cells. Nature 1987, 328: 263-266. PMID: 2885757, DOI: 10.1038/328263a0.Peer-Reviewed Original ResearchConceptsEpidermal cellsT cell receptorDendritic epidermal cellsThy-1Steady-state levelsMurine Thy-1T lymphocytesCell differentiationT-cell lineageT cell differentiationDistinct populationsMost T lymphocytesRNA expressionMajor histocompatibility complexΔ complexNecessary eventΑ-chainΓ-chainMinor populationDendritic cellsLangerhans cellsExpressionCellsNormal miceHistocompatibility complex