2022
Prevention of Oxaliplatin-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis
Peng S, Ying A, Chan N, Sundar R, Soon Y, Bandla A. Prevention of Oxaliplatin-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis. Frontiers In Oncology 2022, 12: 731223. PMID: 35186722, PMCID: PMC8853097, DOI: 10.3389/fonc.2022.731223.Peer-Reviewed Original ResearchOxaliplatin-induced peripheral neuropathyNon-pharmacological interventionsChronic oxaliplatin-induced peripheral neuropathyMeta-analysisSystematic reviewPrevent oxaliplatin-induced peripheral neuropathyGrading of RecommendationsPreventive measuresPooled risk ratioQuality of lifeRandomized controlled trialsPrimary outcome measureRandom-effects modelDatabases PubMed-MEDLINENetwork meta-analysisPreventive interventionsOutcome measuresNo interventionPubMed-MedlinePeripheral neuropathyClinical impactRisk ratioControlled trialsCancer patientsConfidence intervals
2020
Metformin and colorectal cancer: a systematic review, meta-analysis and meta-regression
Ng C, Jiang A, Toh E, Ng C, Ong Z, Peng S, Tham H, Sundar R, Chong C, Khoo C. Metformin and colorectal cancer: a systematic review, meta-analysis and meta-regression. International Journal Of Colorectal Disease 2020, 35: 1501-1512. PMID: 32592092, DOI: 10.1007/s00384-020-03676-x.Peer-Reviewed Original ResearchConceptsColorectal adenomasCancer incidenceImprove colorectal cancer outcomesNon-metformin usersColorectal cancerIncidence of colorectal adenomasMeta-analysisMetformin usersIncidence of colorectal cancerHazard ratioRisk ratioReducing colorectal adenomasColorectal cancer outcomesCRC-specific survivalCancer survival outcomesEffect of metformin useMetformin useSurvival outcomesAdvanced adenomasDiet-only treatmentDerSimonian and LairdCancer outcomesOverall survivalMethodsA database searchConclusionThis meta-analysis