2022
The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder
Weeland CJ, Kasprzak S, de Joode NT, Abe Y, Alonso P, Ameis SH, Anticevic A, Arnold PD, Balachander S, Banaj N, Bargallo N, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Brecke V, Brem S, Cappi C, Cheng Y, Cho KIK, Costa DLC, Dallaspezia S, Denys D, Eng GK, Ferreira S, Feusner JD, Fontaine M, Fouche JP, Grazioplene RG, Gruner P, He M, Hirano Y, Hoexter MQ, Huyser C, Hu H, Jaspers-Fayer F, Kathmann N, Kaufmann C, Kim M, Koch K, Bin Kwak Y, Kwon JS, Lazaro L, Li CR, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minnuzi L, Moreira PS, Morgado P, Nakagawa A, Nakamae T, Narayanaswamy JC, Nurmi EL, Ortiz AE, Pariente JC, Piacentini J, Picó-Pérez M, Piras F, Piras F, Pittenger C, Reddy YCJ, Rodriguez-Manrique D, Sakai Y, Shimizu E, Shivakumar V, Simpson HB, Soreni N, Soriano-Mas C, Sousa N, Spalletta G, Stern ER, Stevens MC, Stewart SE, Szeszko PR, Takahashi J, Tanamatis T, Tang J, Thorsen AL, Tolin D, van der Werf YD, van Marle H, van Wingen GA, Vecchio D, Venkatasubramanian G, Walitza S, Wang J, Wang Z, Watanabe A, Wolters LH, Xu X, Yun JY, Zhao Q, White T, Thompson P, Stein D, van den Heuvel O, Vriend C. The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder. Translational Psychiatry 2022, 12: 70. PMID: 35190533, PMCID: PMC8861046, DOI: 10.1038/s41398-022-01823-2.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderMagnetic resonance imagingThalamic volumeOCD patientsThalamic subregionsT1-weighted brain magnetic resonance imagingBrain magnetic resonance imagingClinical-level symptomsLarger thalamic volumesPediatric OCD patientsAdult OCD patientsSeparate multiple linear regression modelsVolumetric group differencesThalamus sizeMedicated patientsAdolescent patientsAnterior thalamusHealthy controlsSubregional volumesGeneral populationMedication statusMultiple comparison correctionPatientsResonance imagingIntracranial volume
2020
Predictors of conversion to psychosis
Grazioplene R, Cannon T. Predictors of conversion to psychosis. 2020, 113-121. DOI: 10.1093/med/9780190653279.003.0014.ChaptersClinical high riskPopulation-based studyPredictors of conversionPrediction of psychosisNew onsetCHR syndromeFull psychosisProdromal phasePsychosis predictionHigh riskGeneral populationNeuronal connectivityProgressive lossPsychosisFrequent assessmentTransdiagnostic frameworkOnsetSyndromePopulationPrevention
2016
White Matter Correlates of Psychosis-Linked Traits Support Continuity Between Personality and Psychopathology
Grazioplene R, Chavez R, Rustichini A, DeYoung C. White Matter Correlates of Psychosis-Linked Traits Support Continuity Between Personality and Psychopathology. Journal Of Psychopathology And Clinical Science 2016, 125: 1135-1145. PMID: 27819473, PMCID: PMC5117638, DOI: 10.1037/abn0000176.Peer-Reviewed Original ResearchConceptsWhite matter correlatesWhite matter connectivity patternsWhite matter differencesPsychotic spectrum disordersWhite matter connectivityWhite matter microstructureGeneral populationPsychotic disordersProtective roleBrain structuresSubclinical levelsLarge community sampleNeural structuresCommunity sampleConnectivity patternsDisordersEndophenotype studiesSpectrum disorderBiological supportCorrelates