2019
Bleeding Assessment Scale in Critically Ill Children (BASIC): Physician-Driven Diagnostic Criteria for Bleeding Severity.
Nellis ME, Tucci M, Lacroix J, Spinella PC, Haque KD, Stock A, Steiner ME, Faustino EVS, Zantek ND, Davis PJ, Stanworth SJ, Cholette JM, Parker RI, Demaret P, Kneyber MCJ, Russell RT, Stricker PA, Vogel AM, Willems A, Josephson CD, Luban NLC, Loftis LL, Leteurtre S, Stocker CF, Goobie SM, Karam O. Bleeding Assessment Scale in Critically Ill Children (BASIC): Physician-Driven Diagnostic Criteria for Bleeding Severity. Critical Care Medicine 2019, 47: 1766-1772. PMID: 31567407, PMCID: PMC6861687, DOI: 10.1097/ccm.0000000000004025.Peer-Reviewed Original ResearchConceptsIll childrenAssessment ScaleDiagnostic criteriaProspective cohort studyRed cell transfusionCritically Ill ChildrenFuture epidemiologic studiesDelphi consensus processInternational expert consensusRounds of votingBleeding severityRelevant bleedingSubstantial inter-rater reliabilityBleeding episodesCell transfusionCohort studyCritical illnessOrgan dysfunctionOnline Delphi processSurgical interventionPediatric intensivistsPatient outcomesInter-rater reliabilityEpidemiologic studiesExpert consensus
2017
Perceived changes in behavior and values after a red blood cell transfusion
Broccolo M, Favez N, Karam O. Perceived changes in behavior and values after a red blood cell transfusion. International Journal Of Clinical Transfusion Medicine 2017, 6: 1-5. DOI: 10.2147/ijctm.s155338.Peer-Reviewed Original Research
2014
Transfusions de plasma en réanimation pédiatrique
Labarinas S, Arni D, Karam O. Transfusions de plasma en réanimation pédiatrique. Médecine Intensive Réanimation 2014, 23: 455-462. DOI: 10.1007/s13546-014-0900-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAbnormal coagulation testsPlasma transfusionCoagulation testsRed blood cell transfusionNon-bleeding patientsBlood cell transfusionIntensive care unitRecent epidemiological studiesCell transfusionIll adultsIll patientsCare unitRéanimation pédiatriqueFrequent treatmentObservational studyCurrent evidenceEpidemiological studiesTransfusionCoagulation factorsVolume replacementPatientsTreatmentMost expertsIndicationsBleeding
2013
Plasma in the PICU: why and when should we transfuse?
Labarinas S, Arni D, Karam O. Plasma in the PICU: why and when should we transfuse? Annals Of Intensive Care 2013, 3: 16. PMID: 23725411, PMCID: PMC3698065, DOI: 10.1186/2110-5820-3-16.Peer-Reviewed Original ResearchAbnormal coagulation testsPlasma transfusionCoagulation testsRed blood cell transfusionBlood cell transfusionIntensive care unitRecent epidemiological studiesCell transfusionIll adultsIll patientsCare unitFrequent treatmentObservational studyCurrent evidenceEpidemiological studiesCoagulation factorsTransfusionVolume replacementPatientsTreatmentMost expertsIndicationsPICUBleedingMorbidity
2012
Mortality associated with restrictive threshold for red blood cell transfusion in pediatric patients with sepsis
Karam O, Tucci M, Ducruet T, Hume H, Lacroix J, Gauvin F. Mortality associated with restrictive threshold for red blood cell transfusion in pediatric patients with sepsis. Pediatric Critical Care Medicine 2012, 13: 495. DOI: 10.1097/pcc.0b013e31824fbefe.Peer-Reviewed Original Research
2011
Red blood cell transfusion thresholds in pediatric patients with sepsis*
Karam O, Tucci M, Ducruet T, Hume HA, Lacroix J, Gauvin F. Red blood cell transfusion thresholds in pediatric patients with sepsis*. Pediatric Critical Care Medicine 2011, 12: 512-518. PMID: 21057356, DOI: 10.1097/pcc.0b013e3181fe344b.Peer-Reviewed Original ResearchConceptsRed blood cell transfusionBlood cell transfusionProgressive multiple organ dysfunction syndromeMultiple organ dysfunction syndromeOrgan dysfunction syndromeCell transfusionTransfusion thresholdDysfunction syndromeTransfusion strategySubgroup analysisIll childrenPediatric intensive care unit studyRed blood cell transfusion thresholdRestrictive red-cell transfusion strategyCritical care unit admissionRed-cell transfusion strategyIntensive care unit studiesPediatric critical care unitLiberal transfusion strategyRestrictive transfusion thresholdCare unit admissionSubgroup of patientsCritical care unitsTransfusion requirementsUnit admission