2024
Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes
Starosta A, Lundsberg L, Culhane J, Partridge C, Grechukhina O, Son M. Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes. Obstetric Anesthesia Digest 2024, 44: 227-228. DOI: 10.1097/01.aoa.0001080268.73398.1f.Peer-Reviewed Original ResearchShort-term neonatal outcomesNeonatal outcomesAdverse short-term neonatal outcomesAssociated with adverse neonatal outcomesAdverse neonatal outcomesInhaled nitrous oxideLabor analgesiaNeuraxial analgesiaSystemic opioidsNo significant differenceSignificant differenceIntrapartumShort-term effectsAnalgesiaOutcomesInhaled gasUnited StatesAssociationNeonatesOpioidPlacentaPainNitrous oxideReporting Perinatal Substance Use to Child Protective Services: Obstetric Provider Perspectives on the Impact on Care
Kaufman J, Yonkers K, Maltz C, Friedhoff C, Tobon A, Mele A, Tessier-Kay M, Grechukhina O, Lipkind H, Byatt N, Forray A. Reporting Perinatal Substance Use to Child Protective Services: Obstetric Provider Perspectives on the Impact on Care. Journal Of Women's Health 2024, 33: 1501-1508. PMID: 38770764, DOI: 10.1089/jwh.2023.0822.Peer-Reviewed Original ResearchOpioid use disorderProvider perspectiveKey informant interviewsCPS involvementNurse practitionersAffect careObstetric patientsCareInformant interviewsPostpartum patientsReporting requirementsCPS reportsProvidersContent analysisPerinatal individualsUse disorderSocial workersThematic areasPatientsFearNursesMandated reportersObstetriciansPostpartumStaffAssociation Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes
Starosta A, Lundsberg L, Culhane J, Partridge C, Grechukhina O, Son M. Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes. Obstetrics And Gynecology 2024, 143: 677-682. PMID: 38484306, DOI: 10.1097/aog.0000000000005554.Peer-Reviewed Original ResearchShort-term neonatal outcomesNeonatal intensive care unitNo analgesiaNeonatal outcomesApgar scoreLabor analgesiaComposite outcomeAdverse short-term neonatal outcomesNeonatal intensive care unit admissionSecondary outcomesSingle-center retrospective cohortRetrospective cohort study of individualsCohort study of individualsLow-risk patientsRetrospective cohort studyIntensive care unitElectronic medical recordsNitrous oxide useAnalgesia typeIntrapartum cesareanSingleton gestationsNICU admissionNitrous oxide exposureIntrapartum analgesiaNeonatal hyperbilirubinemia
2023
Severe Maternal Morbidity Review and Preventability Assessment in a Large Academic Center
Grechukhina O, Lipkind H, Lundsberg L, Merriam A, Raab C, Leon-Martinez D, Campbell K. Severe Maternal Morbidity Review and Preventability Assessment in a Large Academic Center. Obstetrics And Gynecology 2023, 141: 857-860. PMID: 36897178, DOI: 10.1097/aog.0000000000005116.Peer-Reviewed Original ResearchConceptsSevere maternal morbiditySystem-level factorsYale-New Haven HospitalRetrospective cohort studyHealth careDetailed case reviewLarge academic centerSMM ratesMaternal morbidityCohort studyPreventability assessmentPreventable causeSMM casesMorbidity reviewAmerican CollegeAcademic centersConsensus criteriaCase reviewPractice changeCareCauseMorbidityHemorrhagePreventabilityReview
2022
Seizing the Window of Opportunity Within 1 Year Postpartum: Early Cardiovascular Screening
Ackerman‐Banks C, Grechukhina O, Spatz E, Lundsberg L, Chou J, Smith G, Greenberg VR, Reddy UM, Xu X, O’Bryan J, Smith S, Perley L, Lipkind HS. Seizing the Window of Opportunity Within 1 Year Postpartum: Early Cardiovascular Screening. Journal Of The American Heart Association 2022, 11: e024443. PMID: 35411781, PMCID: PMC9238464, DOI: 10.1161/jaha.121.024443.Peer-Reviewed Original ResearchConceptsHDP groupBody mass indexChronic hypertensionMonths postpartumHypertension 6Metabolic syndromeMass indexYear postpartumFamily historyMedical conditionsNew diagnosisHigh low-density lipoprotein cholesterolLow-density lipoprotein cholesterolEffective primary prevention strategiesPreexisting medical conditionsProspective cohort studyCVD risk scoreUnderlying medical conditionsCardiovascular disease riskMultidisciplinary care modelMultivariable logistic regressionDevelopment of CVDFirst year postpartumPrimary prevention strategiesHypertensive disordersMaternal-fetal medicine fellows’ perception and comfort with obstetrical ultrasound and prenatal diagnosis
Holliman K, Pluym ID, Grechukhina O, Blumenfeld YJ, Platt LD, Copel JA, Han CS. Maternal-fetal medicine fellows’ perception and comfort with obstetrical ultrasound and prenatal diagnosis. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100601. PMID: 35217235, DOI: 10.1016/j.ajogmf.2022.100601.Peer-Reviewed Original Research
2021
Maternal outcomes and risk factors for COVID-19 severity among pregnant women
Vouga M, Favre G, Martinez-Perez O, Pomar L, Acebal LF, Abascal-Saiz A, Hernandez MRV, Hcini N, Lambert V, Carles G, Sichitiu J, Salomon L, Stirnemann J, Ville Y, de Tejada BM, Goncé A, Hawkins-Villarreal A, Castillo K, Solsona EG, Trigo L, Cleary B, Geary M, Bartels H, Al-Kharouf F, Malone F, Higgins M, Keating N, Knowles S, Poncelet C, Ribeiro-do-Valle CC, Surita F, Dantas-Silva A, Borrelli C, Luz AG, Fuenzalida J, Carvajal J, Canales MG, Hernandez O, Grechukhina O, Ko AI, Reddy U, Figueiredo R, Moucho M, Pinto PV, De Luca C, De Santis M, de Campos DA, Martins I, Garabedian C, Subtil D, Bohrer B, Da Rocha Oppermann ML, Wender MCO, Schuler-Faccini L, Sanseverino MTV, Giugliani C, Friedrich L, Scherer MH, Mottet N, Ducarme G, Pelerin H, Moreau C, Breton B, Quibel T, Rozenberg P, Giannoni E, Granado C, Monod C, Mueller D, Hoesli I, Bassler D, Heldstab S, Kölble NO, Sentilhes L, Charvet M, Deprest J, Richter J, Van der Veeken L, Eggel-Hort B, Plantefeve G, Derouich M, Calvache AJN, Lopez-Giron MC, Burgos-Luna JM, Escobar-Vidarte MF, Hecher K, Tallarek AC, Hadar E, Haratz KK, Amikam U, Malinger G, Maymon R, Yogev Y, Schäffer L, Toussaint A, Rossier MC, De Sa RAM, Grawe C, Aebi-Popp K, Radan AP, Raio L, Surbek D, Böckenhoff P, Strizek B, Kaufmann M, Bloch A, Boulvain M, Johann S, Heldstab SA, Bernasconi MT, Grant G, Feki A, Brochut AM, Giral M, Sedille L, Papadia A, Brugger RC, Weber B, Fischer T, Kahlert C, Saines KN, Cambou M, Kanellos P, Chen X, Yin M, Haessig A, Ackermann S, Baud D, Panchaud A. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Scientific Reports 2021, 11: 13898. PMID: 34230507, PMCID: PMC8260739, DOI: 10.1038/s41598-021-92357-y.Peer-Reviewed Original ResearchConceptsSevere maternal outcomesPregnant womenRisk factorsMaternal outcomesPulmonary comorbiditiesHypertensive disordersNeonatal outcomesSevere complicationsHigh riskSevere acute respiratory syndrome coronavirus 2Severe coronavirus disease-19Severe COVID-19 diseaseAcute respiratory syndrome coronavirus 2Neonatal intensive care unitSARS-CoV-2 infectionRespiratory syndrome coronavirus 2Immediate neonatal outcomeIntensive care unitSyndrome coronavirus 2COVID-19 severityCase-control studyCoronavirus disease-19SARS-CoV-2COVID-19 diseaseMaternal disease352 Regional heterogeneity in ultrasound and procedural training in maternal-fetal medicine fellowship: a cross-sectional survey
Holliman K, Pluym I, Grechukhina O, Blumenfeld Y, Platt L, Copel J, Han C. 352 Regional heterogeneity in ultrasound and procedural training in maternal-fetal medicine fellowship: a cross-sectional survey. American Journal Of Obstetrics And Gynecology 2021, 224: s230-s231. DOI: 10.1016/j.ajog.2020.12.373.Peer-Reviewed Original Research
2020
Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population
Grechukhina O, Greenberg V, Lundsberg LS, Deshmukh U, Cate J, Lipkind HS, Campbell KH, Pettker CM, Kohari KS, Reddy UM. Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population. American Journal Of Obstetrics & Gynecology MFM 2020, 2: 100246. PMID: 33047100, PMCID: PMC7539936, DOI: 10.1016/j.ajogmf.2020.100246.Peer-Reviewed Original ResearchMeSH KeywordsAdultCommunicable Disease ControlComorbidityCOVID-19COVID-19 TestingEthnicityFemaleHealth Status DisparitiesHospitalizationHumansInfant, NewbornNew YorkObstetrics and Gynecology Department, HospitalPregnancyPregnancy Complications, InfectiousPregnancy OutcomePremature BirthRisk AssessmentRisk FactorsSARS-CoV-2ConceptsCoronavirus disease 2019Severe acute respiratory syndrome coronavirusAcute respiratory syndrome coronavirusSevere diseaseDisease 2019Pregnancy outcomesPositive test resultsClinical coursePostpartum womenRisk factorsHispanic ethnicityHispanic womenSevere acute respiratory syndrome coronavirus 2Coronavirus disease 2019 courseAcute respiratory syndrome coronavirus 2Severe coronavirus disease 2019Respiratory syndrome coronavirus 2Severe acute respiratory syndrome 2Effect of comorbidityWorse clinical courseC-reactive proteinSyndrome coronavirus 2Hypertensive disordersMedical comorbiditiesObese womenVertical transmission of coronavirus disease 2019: a systematic review and meta-analysis
Kotlyar A, Grechukhina O, Chen A, Popkhadze S, Grimshaw A, Tal O, Taylor HS, Tal R. Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis. American Journal Of Obstetrics And Gynecology 2020, 224: 35-53.e3. PMID: 32739398, PMCID: PMC7392880, DOI: 10.1016/j.ajog.2020.07.049.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Syndrome coronavirus 2Coronavirus disease 2019Case series studyPooled proportionCoronavirus 2Disease 2019Vertical transmissionSystematic reviewNasopharyngeal swabsRNA testNeonatal serologySevere acute respiratory syndrome coronavirus 2 positivitySeries studyCoronavirus disease 2019 (COVID-19) infectionCoronavirus disease 2019 (COVID-19) diagnosisTesting of neonatesDisease 2019 infectionHours of birthNewcastle-Ottawa ScaleViral RNA testingNeonatal cord bloodRate of infection1063: Endometrial and myometrial cell CXCL12 expression in response to mechanical injury: implications for placenta accreta.
Grechukhina O, Popkhadze S, Taylor H. 1063: Endometrial and myometrial cell CXCL12 expression in response to mechanical injury: implications for placenta accreta. American Journal Of Obstetrics And Gynecology 2020, 222: s657. DOI: 10.1016/j.ajog.2019.11.1077.Peer-Reviewed Original Research122: Leading causes and preventability of severe maternal morbidity cases in a large urban referral center.
Grechukhina O, Lundsberg L, O'Bryan J, Merriam A, Raab C, Lipkind H, Campbell K. 122: Leading causes and preventability of severe maternal morbidity cases in a large urban referral center. American Journal Of Obstetrics And Gynecology 2020, 222: s94-s95. DOI: 10.1016/j.ajog.2019.11.138.Peer-Reviewed Original Research938: Yale Hearts Moms Study: Cardiovascular screening in women with pregnancy hypertension 6-12 months after delivery
Lipkind H, Ackerman C, Grechukhina O, Chou J, Spatz E, O'Bryan J, Smith S, Gaeta M, Perley L, Reddy U, Smith G. 938: Yale Hearts Moms Study: Cardiovascular screening in women with pregnancy hypertension 6-12 months after delivery. American Journal Of Obstetrics And Gynecology 2020, 222: s581. DOI: 10.1016/j.ajog.2019.11.949.Peer-Reviewed Original Research
2019
Cesarean Scar Pregnancy, Incidence, and Recurrence: Five-Year Experience at a Single Tertiary Care Referral Center
Grechukhina O, Deshmukh U, Fan L, Kohari K, Abdel-Razeq S, Bahtiyar M, Sfakianaki A. Cesarean Scar Pregnancy, Incidence, and Recurrence: Five-Year Experience at a Single Tertiary Care Referral Center. Obstetric Anesthesia Digest 2019, 39: 98-99. DOI: 10.1097/01.aoa.0000557687.83837.90.Peer-Reviewed Original ResearchCesarean scar pregnancyScar pregnancyTreatment modalitiesSingle tertiary care referral centerTertiary care referral centerYale-New Haven HospitalLife-threatening complicationsNumerous treatment modalitiesTertiary care centerOptimal treatment modalityFive-year experiencePrevious hysterotomySac implantsPregnancy outcomesReferral centerPatient counselingCare centerTreatment decisionsPregnancyAvailable literaturePresent studyModalitiesHysterotomyComplicationsRecurrenceResults From an Multidisciplinary Severe Maternal Morbidity Review at a Tertiary Academic Medical Center [23P]
Campbell K, Grechukhina O, Abdel-Razeq S, Raab C, Pettker C, Lipkind H. Results From an Multidisciplinary Severe Maternal Morbidity Review at a Tertiary Academic Medical Center [23P]. Obstetrics And Gynecology 2019, 133: 176s-176s. DOI: 10.1097/01.aog.0000559487.48795.79.Peer-Reviewed Original ResearchSevere maternal morbidityPreventable severe maternal morbidityTertiary academic medical centerMean maternal ageWomen age 40Academic medical centerObstetric safetyPlacental hemorrhageHypertensive disordersMaternal morbidityObstetric hemorrhagePatient characteristicsMaternal deathsOutside hospitalPotential preventabilityPregnant womenMaternal agePeripartum periodSMM casesCommon causeMedical CenterMaternity careMorbidity reviewAge 40PI women
2017
Cesarean Scar Pregnancy
Deshmukh U, Grechukhina O, Bahtiyar M, Fan L, Sfakianaki A. Cesarean Scar Pregnancy. Obstetrics And Gynecology 2017, 129: s143. DOI: 10.1097/01.aog.0000514712.81512.95.Peer-Reviewed Original ResearchCesarean scar pregnancyLocal methotrexateMethotrexate therapyScar pregnancyExpectant managementCases of CSPKCl injectionBilateral uterine artery embolizationYale-New Haven HospitalMedian gestational agePrior cesarean deliveryTime of diagnosisUterine artery embolizationRisk of complicationsCesarean delivery rateFetal cardiac activityProducts of conceptionElectronic medical recordsInstitutional review boardSpontaneous demiseSystemic methotrexateArtery embolizationCesarean deliveryIntrauterine gestationWedge resection
2015
GnRH-agonist Ovulation Induction May Be Insufficient to Trigger Follicular Maturation in the Patient with Hypothalamic Hypogonadism
Grechukhina O, Duke C, Kallen A, Grant S, Patrizio P, Pal L. GnRH-agonist Ovulation Induction May Be Insufficient to Trigger Follicular Maturation in the Patient with Hypothalamic Hypogonadism. Fertility And Sterility 2015, 103: e22-e23. DOI: 10.1016/j.fertnstert.2014.12.038.Peer-Reviewed Original Research
2011
microRNA 135a expression regulates HOXA10 in endometriosis
Petracco R, Grechukhina O, Popkhadze S, Massasa E, Zhou Y, Taylor H. microRNA 135a expression regulates HOXA10 in endometriosis. Fertility And Sterility 2011, 96: s133. DOI: 10.1016/j.fertnstert.2011.07.517.Peer-Reviewed Original Research