2024
Protein Intake and High Uric Acid Stone Risk
Montgomery T, Nair H, Phadke M, Morhardt E, Ludvigson A, Motamedinia P, Singh D, Dahl N. Protein Intake and High Uric Acid Stone Risk. Kidney Medicine 2024, 6: 100878. PMID: 39279882, PMCID: PMC11399574, DOI: 10.1016/j.xkme.2024.100878.Peer-Reviewed Original ResearchUric acid stone formersKidney stone formersUric acid stone formationStone formersChronic kidney diseaseStone analysisProtein intakeRetrospective studyKidney functionKidney diseaseAssociated with protein intakeUric acidStone formationLow urine citrateDietary protein intakeDiminished kidney functionProtein catabolic rateBody mass indexUrine urea nitrogenUric acid nephrolithiasisChi-square testPrevalence of uric acid nephrolithiasisUrine citrateNephrology clinicMass indexBiomarkers of Kidney Disease Progression in ADPKD
Ghanem A, Borghol A, Debeh F, Paul S, AlKhatib B, Harris P, Garimella P, Hanna C, Kline T, Dahl N, Chebib F. Biomarkers of Kidney Disease Progression in ADPKD. Kidney International Reports 2024, 9: 2860-2882. PMID: 39435347, PMCID: PMC11492289, DOI: 10.1016/j.ekir.2024.07.012.Peer-Reviewed Original ResearchAutosomal dominant polycystic kidney diseaseDominant polycystic kidney diseaseKidney disease progressionPolycystic kidney diseaseDisease progressionMonogenic kidney disorderKidney diseaseHeight-adjusted total kidney volumeDisease severityTotal kidney volumePKD1 geneGlomerular filtration rateMayo imaging classificationBody mass indexPersonalized treatment strategiesIncreased kidney sizePathogenic variantsEfficacy of treatmentAssess disease severityTotal cyst volumeGenetic profileImprove patient outcomesPredictive biomarkersCyst volumeKidney volume
2023
Risk Factors for Common Kidney Stones Are Correlated with Kidney Function Independent of Stone Composition
Simmons K, Nair H, Phadke M, Motamedinia P, Singh D, Montgomery T, Dahl N. Risk Factors for Common Kidney Stones Are Correlated with Kidney Function Independent of Stone Composition. American Journal Of Nephrology 2023, 54: 329-336. PMID: 37253348, DOI: 10.1159/000531046.Peer-Reviewed Original ResearchConceptsEstimate glomerular filtration rateLower estimate glomerular filtration rateRisk factorsUrine chemistryUnivariable analysisMultivariable analysisStone compositionKidney stonesKidney stone risk factorsCommon stone compositionUrine risk factorsRetrospective cohort studyStone analysisStone risk factorsGlomerular filtration rateLow urine pHBody mass indexKidney stone patientsCalcium-containing stonesUric acid stonesStone composition dataUrine oxalateRenal functionCohort studyKidney function