2008
Dose-dependent reduction of hazardous alcohol use in a placebo-controlled trial of naltrexone for smoking cessation
O'Malley SS, Krishnan-Sarin S, McKee SA, Leeman RF, Cooney NL, Meandzija B, Wu R, Makuch RW. Dose-dependent reduction of hazardous alcohol use in a placebo-controlled trial of naltrexone for smoking cessation. The International Journal Of Neuropsychopharmacology 2008, 12: 589-597. PMID: 18796184, PMCID: PMC3094855, DOI: 10.1017/s146114570800936x.Peer-Reviewed Original ResearchConceptsHazardous drinkingSmoking cessationFavorable side effect profileDose-ranging clinical trialAlcohol useEffects of NTXPlacebo-controlled trialDose-ranging trialSide effect profileTransdermal nicotine patchOpiate antagonist naltrexoneDose-dependent reductionComponent of treatmentHazardous alcohol useOral NTXSecondary outcomesNicotine patchPrimary outcomeAntagonist naltrexoneCombination therapyClinical trialsBaseline predictorsOral preparationsHazardous drinkersNTX
1998
Compliance with Treatment and Follow‐up Protocols in Project MATCH: Predictors and Relationship to Outcome
Mattson M, Del Boca F, Carroll K, Cooney N, DiClemente C, Donovan D, Kadden R, McRee B, Rice C, Rycharik R, Zweben A. Compliance with Treatment and Follow‐up Protocols in Project MATCH: Predictors and Relationship to Outcome. Alcohol Clinical And Experimental Research 1998, 22: 1328-1339. PMID: 9756050, DOI: 10.1111/j.1530-0277.1998.tb03916.x.Peer-Reviewed Original ResearchConceptsStrongest baseline predictorsMultisite clinical trialProject MATCHClinicians/investigatorsPatient-treatment matchingTreatment complianceClinical trialsBaseline predictorsDrinking outcomesTherapy sessionsTreatment deliveryResearch protocolTreatment environmentFollowHigh rateTreatmentFuture studiesResearch followCompliancePredictorsAttendance dataPrevious studiesPatientsTherapyTrialsCompliance with Treatment and Follow-up Protocols in Project MATCH
Mattson M, Del Boca F, Carroll K, Cooney N, DiClemente C, Donovan D, Kadden R, McRee B, Rice C, Rycharik R, Zweben A. Compliance with Treatment and Follow-up Protocols in Project MATCH. Alcohol Clinical And Experimental Research 1998, 22: 1328. DOI: 10.1097/00000374-199809000-00020.Peer-Reviewed Original ResearchStrongest baseline predictorsMultisite clinical trialProject MATCHClinicians/investigatorsPatient-treatment matchingTreatment complianceClinical trialsBaseline predictorsDrinking outcomesTherapy sessionsTreatment deliveryResearch protocolTreatment environmentFollowHigh rateTreatmentFuture studiesResearch followComplianceAttendance dataPrevious studiesPatientsTherapyTrialsTreatment integrity