2022
Translating virus evolution into epidemiology
Grubaugh ND. Translating virus evolution into epidemiology. Cell Host & Microbe 2022, 30: 444-448. PMID: 35421340, DOI: 10.1016/j.chom.2022.03.006.Peer-Reviewed Original Research
2021
Intrahost speciations and host switches played an important role in the evolution of herpesviruses
Brito AF, Baele G, Nahata KD, Grubaugh ND, Pinney JW. Intrahost speciations and host switches played an important role in the evolution of herpesviruses. Virus Evolution 2021, 7: veab025. PMID: 33927887, PMCID: PMC8062258, DOI: 10.1093/ve/veab025.Peer-Reviewed Original ResearchIntrahost speciationHost switchingHost switchesEvolutionary historyTree reconciliationTree reconciliation analysesEvolution of herpesvirusesViral phylogenyHost biogeographyDivergence timingTopological incongruenceCophylogenetic analysesReconciliation analysisHost evolutionPhylogenetic differencesSequence dataGenomic dataViral speciesPhylogenyTemporal incongruenceCospeciationSpeciationImportant roleHostIncongruence
2016
Transmission bottlenecks and RNAi collectively influence tick-borne flavivirus evolution
Grubaugh ND, Rückert C, Armstrong PM, Bransfield A, Anderson JF, Ebel GD, Brackney DE. Transmission bottlenecks and RNAi collectively influence tick-borne flavivirus evolution. Virus Evolution 2016, 2: vew033. PMID: 28058113, PMCID: PMC5210029, DOI: 10.1093/ve/vew033.Peer-Reviewed Original ResearchSimilar selective pressuresMicro-evolutionary forcesGreat genetic plasticityArthropod-borne RNA virusesVirus populationsLong-term evolutionary trendsGenetic bottleneckSelective constraintsFlavivirus evolutionEcological nichesGenetic plasticitySelective pressureVertebrate hostsPopulation dynamicsArthropod-borne virusesRNA virusesEvolutionary trendsArthropod vectorsMolecular levelMechanistic explanationTransmission bottleneckHostHeterogeneous populationUnique rateRNAi