Proteome-wide Analysis of Lysine Acetylation Suggests its Broad Regulatory Scope in Saccharomyces cerevisiae *
Henriksen P, Wagner SA, Weinert BT, Sharma S, Bačinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Proteome-wide Analysis of Lysine Acetylation Suggests its Broad Regulatory Scope in Saccharomyces cerevisiae *. Molecular & Cellular Proteomics 2012, 11: 1510-1522. PMID: 22865919, PMCID: PMC3494197, DOI: 10.1074/mcp.m112.017251.Peer-Reviewed Original ResearchMeSH KeywordsAcetylationConserved SequenceEvolution, MolecularIonsLysineMolecular Sequence AnnotationNuclear ProteinsProtein TransportProteomeProteomicsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsConceptsAcetylation sitesLysine acetylationS. cerevisiaeUnicellular eukaryotic model organismBudding yeast Saccharomyces cerevisiaeRegulatory roleBroader regulatory scopeProtein synthesisEukaryotic model organismYeast Saccharomyces cerevisiaePost-translational modificationsLysine acetylation sitesImportant regulatory roleChromatin organizationLysine acetyltransferasesModel organismsWide analysisPutative substratesRegulatory domainCritical regulatory domainsHistone H2BAcetylated proteinsProtein foldingSaccharomyces cerevisiaeBioinformatics analysis